nervous system (chapter 3 and 4) Flashcards
nerve cells
- neurons
- basic structure and functional unit of nervous system
- highly specialised cells, designed for rapid communication of messages in the body
structure of neurons
cell body:
- contains the nucleus
- responsible for controlling the functioning of the cell
- surrounding nucleus is cytoplasm and organelles
dendrites:
- extensions of the cytoplasm of cell body
- highly branched structure that carry nerve impulses
axon:
- a long extension of the cytoplasm
- carrying nerve impulses away from cell body
- ends by dividing into axon terminals
myelin sheath:
- fatty material
- the gaps between are called nodes of Ranvier
- Schwann cells are the nodes of myelin
- main functions include: insulating, protecting axon from damage and increasing the speech of impulses
- in the central nervous system, myelin sheath is produced by oligodendrocytes
synapse between neurons
- a gap that’s between the axon terminals of one neurons and the dendrites of another neuron
- impulses are carried across the synapse occurs by the movement of chemicals (neurotransmitters)
- the synapse between a neuron and skeletal muscle is called a neuromuscular junction
types of neurons (functional)
sensory:
- a.k.a afferent or receptor neurons
- carry messages from receptors in the sense organs, or skin, to central nervous system
motor:
- a.k.a efferent or effector neurons
- carry messages from central nervous system to effectors in the muscles and glands
interneuron:
- a.k.a relay, association or connector neurons
- located in CNS
- link between sensory and motor
types of neurons (structural)
multipolar:
- one axon and multiple dendrites extending from cell body
- can be motor neurons or interneurons
bipolar:
- one axon and one dendrite
- sensory afferent (eye, ear and nose - specialised)
pseudounipolar:
- one axon extending from cell body, which then separates into 2 extensions. one extension connects to axon terminals and the other to dendrites.
- cell body lies to the side of the main axon.
- sensory (afferent) neuron
conduction of a nerve impulse
- a nerve impulse is a electrochemical change that travels along a nerve fibre
- involving a change in electrical voltage brought about by chemicals (concentration of ions inside and outside of the cell membrane of a neuron)
electrical change and potential difference
- 2 types of electrical charges: (+) and (-)
- like charges repel, opposites attract
- when opposite charges are separated, an electrical force tends to pull them together, which can be measured (in voltage by volts or millivolts - 1000mV = 1V)
- when opposite charges come together energy is released
- if a group of opposites are separated they have the potential (potential difference) to come together and release energy
potential difference across cell membrane
- when come chemical substances dissolve in water they break up into charged particles, ions this happens in:
- the extracellular fluid, which contains a high concentration of sodium chloride (NaCl) - Na+ and Cl-
- the intracellular fluid, which contains less sodium chloride and more potassium ions (K+) and other negative ions from organic particles
- the difference in the concentration of ions means there is potential inside and outside the cell, called membrane potential
- the membrane potential of an unstimulated neuron is resting membrane potential, is measured at approx. -70mV (means that the potential inside the cell is 70mV less that outside) and due to the differences in distribution of K+ and Na+ = extra being more positively charged than intra.
- there is 10x more Na+ extra than intra
- cell membrane is only slightly permeable to sodium ions due to the limited number of sodium leakage (limiting the facilitated diffusion of sodium)
- the concentration of K+ is 30x more intra than extra
- membrane is highly permeable to K+ due to larger number of K+ leakage channels = more K+ than Na+ can diffuse
- the concentration of chloride ions is > intra then extra
- membrane is highly permeable to Cl- allowing their diffusion through protein channels
movement of ions through membrane
cannot diffuse through phospholipid bilayer directly, either through:
- leakage channels: are always open
- voltage-gated channels: only open once the nerve is stimulated
types of receptors
- thermoreceptors
- osmoreceptors
- chemoreceptors
- mechanoreceptors
- nocicereceptors
thermoreceptors
- are able to respond to heat or cold
- thermoreceptors in the skin inform the brain of changes in the temperature outside the body
- peripheral receptors in the skin and nerve endings are sensitive to either hot or cold temperatures (not both)
- the core body temperature is monitored by thermoreceptors in the hypothalamus which can then regulate body temperature
osmoreceptors
- osmotic pressure is determined by the concentration of substances dissolved in the water of the blood plasma
- the higher the concentration the higher osmotic pressure and vice versa
- they are located in the hypothalamus and are highly sensitive
- they stimulate the modulation of water levels in the blood (nephrons of the kidneys)
chemoreceptors
- are stimulated by particular chemicals
- are present in the nose (to odours), mouth (sensitivity to taste)
- internal chemoreceptors (in blood vessels) which are sensitive to body fluid composition, mainly the pH of the blood (H-), oxygen and carbon dioxide (regulation of breathing)
mechanoreceptors
- touch receptors
- are found in greater concentrations in the lips, fingertips and eyelids to ensure quick reflexes to protect oneself
nocicereceptors
- pain receptors
- are found in the skin and do not adapt to ongoing stimulation
- they are stimulated by damage to the tissue, poor blood flow or excessive stimulation from stimuli (heat/chemicals)