Nervous System Flashcards
Brain is protected by
the skull
Spinal cord is protected by
the backbone
Brain and spinal cord are bathed in
cerebrospinal fluid, CSF
2 types of cortical cells
- projections neurons (pyramidal cells)
- local interneurons
Projections neurons are
excitatory
Local interneurons are
inhibitory (GABA)
5 components of a neuron
- cell body
- dentrites
- axon
- myelin sheath
- synaptic terminals
Nodes of Ranvier are
where voltage gated ion channels are activated
Membrane is impermeable for
charged ions
Equation that takes into consideration one type of ion
Nerst Equation
Equilibrium resting potential of membrane
- 70mV
Action potential
+55 mV
When the neuron is at rest the resting potential is mainly governed by
the potassium equilibrium potential
The equation that takes into consideration all ions and their permeability is
Goldman Equation
Goldman Equation terms are:
- ion concentration, ion permeability, temperature, gas constant and faraday’s constant
at resting membrane potential, voltage gated channels are
closed
there is potassium current flowing outwards during
the refractory period
the patch clamp experiment measures the current in
a single ion channel
4 characteristics of electrical synapse
1 - usually bidirectional
2 - in gap-junction channels
3 - virtually no synaptic delay
4 - there is cytoplasmic continuity between pre and postsynaptic cells
3 characteristics of chemical synapse
1 - unidirectional
2 - needs a chemical transmitter - neurotransmitter
3 - there is a delay (1-5 ms)