Nervous System Flashcards
Neuron is made up of three basic parts
- Cell Body
- Dendrite
- Axon
The Neuron
is the structural unit or building block of the nervous
system
Cell body
The neuron cell body contain the organelles that are
common to all cells: a cell membrane, nucleus, endoplasmic reticulum, and cytoplasm
Dendrites
a short branched extension of a neuron, along which
impulses received from other cells at synapses are transmitted to the cell body.
Axon
a long, thin process extending from the cell body. The axon’s cell membrane incorporates specialized protein ion channels that enable the axon to conduct an electrochemical signal (action potential) from the cell body to the axon terminals. Axon terminals of one neuron make synaptic contacts with other neurons’ dendrites or
on the cell body itself
Synapse
When the action potential reaches the axon terminals, a
neurotransmitter is released from synaptic vesicles into the terminals. The neurotransmitter molecules act on receptor molecules that are part of ion channels in the dendrites and soma of the next neuron in a chain.
A typical chemical synapse consists of
a terminal bouton (a swelling at the end of an axon terminal) that includes a presynaptic membrane, a
specialized postsynaptic membrane, and a space between the two (the synaptic cleft). The terminal bouton contains many synaptic vesicles that contain neurotransmitter molecules.
presynaptic and postsynaptic regions contain
numerous mitochondria, which supply the energy needed by the synaptic transmission process
Types of Neurons:
1) Unipolar
2) Bipolar
3) Multipolar
4) Special types: Purkinje, Stellate, Pyrimidal
Special Histological Stains for Nerve Tissue
- Golgi preparations: Great for isolating individual neurons for viewing.
- Nissl preparations: Great for demonstrating cell bodies of neurons.
- Myelin preparations: Stain myelinated fibers and not the cell bodies or dendrites.
- H&E preparations (Haematoxylin & Eosin): usually used for normal nerve tissue staining.
central nervous system (CNS)
the brain and spinal cord
peripheral nervous system (PNS)
nerves and ganglia
Collections of axons that carry action potentials from one place to another are called in the PNS are called
nerves
Collections of axons that carry action potentials from one place to another are called in the CNS
tracts
Clusters of neuron cell bodies in the PNS are called
ganglia
Clusters of neuron cell bodies in the CNS are called
nuclei or cortices
Glial Cells:
Non-neural cells that provide a variety of support functions for the neurons that relate to nutrition, regulation of the extracellular environment
including the blood-brain barrier, immune system, myelin insulation for many axons, and a host of other support function
Astrocytes
found throughout the CNS
Astrocytes regulate
the ionic composition and pH of the extracellular environment and secrete various neuroactive
substances.
Astrocyte end-feet form the
glia limitans, a coating of the inner surface of the pia mater that surrounds the brain and spinal cord