Nervous system

Question 1

Black box warning for Carbamazepine

Answer 1

Severe derm reactions. Especially pts of asian decent. Seven Johnson syndrome.

Also can cause aplastic anemia.

Question 2

Valproic acid monitor:

Answer 2

Depakote, depakene
-May cause liver failure, monitor LFT

Question 3

Anorexants

Answer 3

Use: Short term (3 months tops) for weight loss

Related to amphetamines. Stimulate release of norepinephrine/dopamine.

Question 4

Do not take anorexants with:

Answer 4

SSRI (increased risk of serotonin syndrome)

MAOIs (Increased risk of HTN crisis)

Question 5

First line Tx for tonic clonic and partial complex seizures:

Answer 5

hydantoins
(ethotoin, phenytoin)

Question 6

Black box warning for hydantoins (vampiric acid, carbamazepine)

Answer 6

may cause BLOOD dycrasias

Question 7

Avoid __________ when taking carbamazepines

Answer 7

Grapefruit juice

Question 8

Antidepressant first line

Answer 8

SSRIs (fluoxetine, paroxetine, sertraline, citalopram)

Question 9

NNSRI

Answer 9

VERY likely to overdose. Only prescribe 1 week at a time!

(ex. amitriptyline, nortriptiline)

Question 10

Serotonin syndrome from SSRI/SNRI and _______

Answer 10

tramadol, or st. johns wart.
May be life threatening.

Question 11

Headaches first line tx

Answer 11

Naproxen

Question 12

Antidepressant for pediatrics

Answer 12

Fluoxetine (SSRI)

Question 13

Headache 2nd line treatment

Answer 13

Sumatriptan

(no more than 2 doses in 24hrs)
(do not use in pregnancy)

Question 14

Tx for cluster headaches

Answer 14

100% oxygen