Nervous and Musculoskeletal Systems Flashcards
What can we do to protect musculoskeletal system with anesthesia?
- With sedation, regional or general anesthesia, we take away the normal protective pain reflexes
- Determine preop range of motion abnormalities and joint integritu (document baseline)
- maintain natural range of motion for all anesthetic procedures and sx positioning (document)
What is thoracic outlet syndrome?
- Compression of brachial plexus and SCL vessels near the first rib
- be certain patient can work or sleep with arms elevated over their head before putting arms beside hear (prone positioning)
How do you perform musculoskeletal assessment for the hip?
- Concentrate on ROM that can impact positioning
- flexion- supine, pt bends each knee to chest/abdomen
- abduction- supine pt, stabilize anterior superior iliac spine and abduct the extended leg until the iliac spine moves= limit
What are some consideraitons when patient is on steroids?
- Suppression or disease of pituitary-adrenal axis will prevent the patient from responding to the stress of sx appropriately
- any patient who has received corticosteroid therapy (suppression of pituitary-adrenal aix) for at least a month in the past 6-12 months needs supplementation
What are some considerations when patient on MAOI?
7 MAO-Is
Patients maybe on MAO-Is for depression or parkinson’s (MAO-I type B)
- Inhibits degradation of monoamines, increasing the serotonin and norepi available at presynaptic nerve terminal for uptake and storage
- life-threatneing interactions can occur with consumption of foods containtin tyramine and with Ephedrine and Meperidine
MAO-Is: 7
- iproniazid
- phenelzine
- isocarboxazid
- moclobemide
- befloxatone
- brofaromine
- selegiline
What are the MAOIs we need to know?
8
- Befloxatone
- Brofaraomine
- Iproniazid
- Isocarboxazide
- Moclobemide
- Phenelzine
- Selegiline
- Tranylcypromine
What are some considerations with methotrexate and anesthesia?
used
SE -5
tests
- Used in MS, ankylosing spondylitis and rheumatoid arthritis
- immuno-suppression,
- anemia,
- thrombocytopenia,
- pulmonary toxicity,
- renal and hepatic toxicity
- CBC
- Chem panel
- consider PFT, and LFT if hisotry warrants
What are some quesitons to ask for patient with multipel sclerosis?
- Any recent history of illness or infection?
- Take extra care with infection prevention
- Which medications are they taking and how often?
- Steroids in past year?
- Remission and exacerbation intervals
- Severity and nature of symptoms
- respiratory status
- previous triggers
If on interferon B, will have to stop taking NSAIDs for 48 hours prior to surgery
Anesthetic considerations for patient on disease modifying therapy for MS?
- Disease modifying therapy (immunomodulators) all aincrease risk of infection
- interferon B (flu like symptoms, hepatotoxicity, myelosuppression, depression)
- dimethyl fumarate (GI disocmfort, infections)
- Glatiramer acetate (well tolerated)
- Natalizumab (leukoencephalopathy, hepatotoxicity)
- Fingolomid (bradycardia, hepatotoxicity)
- Teriflunomide (neutropenia, hepatotoxicity)
don’t need to memorize drugs, but know what to assess for in general!
What are some considerations for immunosuppressant drugs around mutliple sclerosis?
- Corticosterois (exacerbations)
- elevated BG levels, DM, Cushings type picture
- mitoxantrone (severe myelosuppressiona nd cardiac toxicity- reduced EF- heart failure)
What are some symptom management treatments in MS?
- Bladder dysfucntion (alpha antagonist, anticholinergics VS bethanechol- agonist)
- Fatigue and depression
- cognitive dysfucntion (cholinesterase inhibitos, memantine)
- neuropathic pain
- spasticity (baclofen)
What is it important to document with MS?
6
document pre-eixsting deficits!
- paralysis (assess for motor strength)
- sensory distubances (assess along dermatomes)
- autonimc distrubance (resting HR, orthostatic hypotension)
- visual impairment (cranial nerve check)
- seizures (meds)
- emotional disturbances
Counsel pt regarding increased relapse incidence with surgery
What is important to dcoument with GBS?
illness
symptoms - 6
-
Document time course of the disease
- precipitating factors
- onset of symptoms
- disease progression (worsening, stable, improving)
- should never, ever do elective procedures with GBS
-
Document severity and current states of symptoms
- facial paralysis- bulbar involvemet
- difficult swallowing- pharyngeal muscle weakness
- impaired ventialtion- current ventilatory support required (vent)
- decreased DTR- lower motor neurons
- extremity paresthesia
- pain- HA, backache, muscle tenderness + note meds helpful for contorlling pain
What is important to note with parkinson’s diases?
- Age of dx,
- recent exacerbation and
- recent hospitalizations
- Current and past symptoms
- (oculogyric crisis- loosing contorl eye movement, staring striaght ahead. How long did it last? What helped?)
- ANS symptoms (orhtostatic BPs)
- hx of pergolide therapy - aortic/mitral regurg
- Temp regulation issues?
- Pulmonary status optimized
- dysphagia and/or dyspnea
- pulmonary infection
-
Continue current meds and note s/e
-
levodopa- what happens if patient misses a dose?
- need dose every 6 hours
- anticohlinergics and MAOIs
-
levodopa- what happens if patient misses a dose?
- Note natural range of motion for positioning
- deactivate deep brain stimulators before electrocautery
Considerations for intervertebral disc herniation?
- Natural ROM for positioning and laryngoscopy
- baseline motor strength and sensation in applicable areas
- med regimen (pt on high dose opioids), what drug improve pain, what has been ineffective
- consider potential for operative blood loss
- CBC
- Type and cross
Consideration for ankylosing spondylitis?
- Evaluate coexist vasculitis, aortitis, aoritc insuff., pulmonary fibrosis
- evaluate for severity of kyphosis
- spo2, ekg, echo, cxr, pft
- CBC, BUN, Cr
- D/c nsaids at least 2 days preo
- may have positioning challenges
Considerations for acute SCI?
- Fluid and blood status
- CBC, T&C, chem7
- EKG/CXR
- Vasopressor requirement?
- Vent support?
- Associated injuries
level of lesion?
Consideration for chronic SCI?
- Hx of autnomic dysreflexia? What intitiated it?
- Old OR/ICU records helpful- response to vasopressors/tracheal sxn
- Ventilatory reserve - level of lesion
- assessment of skin integrity
- positioning- note normal ROM