Nerves Flashcards
What are the different types of glia cells found in the CNS?
Olgiodendrocytes (for myleination), astrocytes (blood brain barrier, physical support), epemdym (lining the ventricles and the central canal p.
What are the different types of glia found in the PNS?
Schwann cell (myleinate a single axon), satilliite cells which provide the physical support for neurones, and mircoglia, which have an immune and inflammatory function.
What is the percentages of glia and neurones found in the body?
90% glia, 10% neurones
What are the two key parts of an neurone?
The cell body and the axon
What are some of the cell histological features of a cell body?
The nucleus and nueclous, golgi appartus which packages transmitters into vesicles and nissi substance for protein synthesis.
What is a collection of cell bodies referred to as?
The grey matter in the CNS, and a ganglion in the PNS
What are some of the features of axons?
In myelinated axons , a Schwann cell wraps itself around the axon about 100 times, level of myelination varies between neuronal types, myelinated axons tend to be thicker (greater than 1um will conduct faster with a myelin sheath whereas less than 1 um will conduct slower with a myelin sheath.
What are the nodes of ranvier?
This are the gaps between the neurone where polarisation occurs in nerve cells.
What are the different diseases that can result from demyelination?
Multiple sclerosis, polyneuropathies, diabetes, gullian bare.
What are the different envelopes in the PNS?
The epineurium which ensheathes the entire nerve and has interfascular attachments, the perineurium which ensheathes a nerve fascicle, and the endonerium which ensheathess a single cell axon.
What are the membranous envelopes on the CNS?
Dura matter, archanoid matter, pia matter.
How does nerve severing result in wallerian degeneration?
The proximal section of a nerve seals up to prevent leakage and a nerve stump is formed, which cuts of the distal section from nutrients leading it to die, and so the process of wallerian degeneration is nessediated.
How does nerve severing result in wallerian regeneration?
The proximal section sells and the cell body suddenly swells up with increased contents, the nucleus is displaced from the centre to the side margins, known as chromatolysis and then the axon usually regrows by wallerian regeneration.
What are the two types of nerve cells?
Neurones and glia
What are some key features of the central nervous system?
Contains the brain (cranium) and the spinal cord (vertebral column) both pf which are incased by bone, and suspended in cebrospinal fluid