Nerve cells and nerve impulses Flashcards

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1
Q

What is the nervous system?

A

The communication network and control centre of the body. Maintains a constant environment inside the body

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2
Q

What are neurons?

A

the basic structural and functional units of the nervous system

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3
Q

What is the myelin sheath

A

a layer of fatty material (in the CNS), cover the Schwann cells

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4
Q

Node of ranvier

A

gaps in the myelin sheath

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5
Q

Axon

A

carried nerve impulses away from the cell body

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6
Q

What are the functional types of neurons?

A

Afferent
Efferent
Interneurons

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7
Q

Afferent (sensory neurons)

A

carry messages from receptors in the sense organs, or in the skin, to the central nervous system

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8
Q

Efferent (motor neurons)

A

carry messages from the central nervous system to the muscles and glands (the effectors)

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9
Q

Inter-neurons (association or connector neurons)

A
  • located in the central nervous system

- They are the link between the sensory and motor neurons

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10
Q

What are the structural types of neurons?

A

Multi-polar
Bipolar
Unipolar

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11
Q

Multipolar neurons

A
  • Have one axon and multiple dendrites extending from the cell body
  • The most common type
  • Includes most of the interneurons in the brain and spinal cord and also the motor neurons
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12
Q

Bipolar neurons

A
  • Have one axon and one dendrite

- Occur in the eye, ear and nose, where they take impulses from the receptor cells to other neurons

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13
Q

Unipolar neurons

A
  • Have just one extension, an axon
  • The cell body is to one side of the neuron
  • Most sensory neurons
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14
Q

What is a neuron

A

A nerve cell

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15
Q

What is a nerve fibre

A

Any long extension of cytoplasm of a nerve cell body, although the term usually refers to an axon

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16
Q

What is a nerve

A

A bundle of nerve fibres held together by connective tissue

17
Q

What is a synapse?

A
  • The junction between the branches of adjacent neurons

- Usually occur between the axon of one neuron and a dendrite or cell body of another neuron

18
Q

What is a nerve impulse?

A
  • An electrochemical change that travels along a nerve fibre

- Is due to the changes in the concentration of ions inside and outside the cell membrane

19
Q

Nerve impulses in un-myelinated fibres

A

Travel steady along the fibre

20
Q

Nerve impulses in myelinated fibres

A

Impulse jumps from one node of Ranvier to the next. Known as salutatory conduction and allows the impulse to travel a lot faster

21
Q

What is salutatory

A

when the impulse jumps form one node of Ranvier to the next

22
Q

What does extracellular fluid contain?

A

A high concentration of sodium ions

23
Q

What does intracellular fluid contain?

A

A high concentration of potassium ions

24
Q

Why does the inside have a relatively negative charge?

A

Because there are less potassium ions than sodium ions

25
Q

What is the membrane potential?

A

The potential difference in sodium and potassium ions

26
Q

What is the resting membrane potential?

A
  • The membrane potential of an unstimulated nerve cell
  • Can be measured and is about -70mV
  • This means that the potential of the inside is 70mV less than the outside
  • The neuron is said to be polarised
27
Q

What is the sub-threshold level?

A

the strength of an impulse needed for the cell membrane to become permeable to sodium ions (opening of the voltage gated sodium channels). Is usually about 15mV

28
Q

What causes depolarisation

A

The opening of the sodium gates causing the Na+ to move into the cell

29
Q

What causes the neuron to be repolarised?

A

Tthe closing of the sodium channels and the opening of the potassium channels

30
Q

What is the role of the sodium potassium pump?

A

To return the membrane to its original state

31
Q

What is the refractory period?

A

The brief time after the action potential where that part of the nerve fibre cannot be stimulated

32
Q

What happens with nerve impulses across the synapse?

A
  • When the action potential reaches the axon terminals, there is an influx of Ca2+
  • This causes neurotransmitters to be released and diffuse across the synapse, attaching to receptors of the next neuron, thus stimulating the next action potential
33
Q

Nerve impulses at the neuromuscular junction

A
  1. The action potential reaches the axon terminal
  2. This opens the calcium gates in the axon terminal membrane
  3. Extracellular Ca2+ move into the axon terminal
  4. This causes the neurotransmitter to be released (acetylcholine) into the synapse
  5. The neurotransmitter attaches to receptors on the muscle membrane
  6. This part of the muscle membrane is called the motor end plate
  7. The attachment of the neurotransmitter causes the opening of sodium gates
  8. Extracellular sodium ions move into the muscle fibre
  9. The sodium depolarises the muscle cell
  10. Depolarisation of the muscle cell causes the release of Ca2+ from the sarcoplasmic reticulum
  11. This calcium causes the actin and myosin myofilaments to slide over each other
  12. This makes the sarcomere shorter. The muscle is now contracted
  13. Acetylcholinesterase is an enzyme that breaks down acetylcholine
  14. The broken down acetylcholine is reabsorbed by the axon terminal and is recycled