Nephrotoxic Drugs

Question 1

Describe the drugs that cause vasoconstriction or haemodynamic alterations.

Answer 1

1. NSAIDS
2. ACE-Inhibitors
3. ARBs
4. Calcineurin Inhibitors.

Question 2

Describe the drugs that cause Direct Tubular Toxicity.

Answer 2

1. Aminoglycosides
2. Amphotericin
3. Radicontract Agents
4. Chemotherepeutic Agents(Cisplatin, Ifosfamide)

Question 3

Describe drugs that cause Interstitial Nephritis

Answer 3

1. NSAIDS
2. Sulphonamides
3. Ciprofloxacin
4. Diuretics (Loop and Thiazides)
5. Anti-convulsants

Question 4

Describe drugs that cause crystal formation

Answer 4

1. Methotrexate
2. Acyclovir 3.Sulphonamides

Question 5

Describe drugs that cause Glomerular Injury/ Podocytopathy

Answer 5

1. Lithium
2. NSAIDS

Question 6

Describe drugs that cause Osmotic Nephrosis

Answer 6

Mannitol

Question 7

Drugs that cause Nephrotic Syndrome

Answer 7

NSAIDS
LITHIUM
ANTIBIOTICS
BISPHOSPHATES