Nephrotic Syndrome Flashcards

1
Q

Key features of nephrotic syndrome:

A

Proteinuria (>3.5g/day)

Hypoalbuminemia
Hyperlipidemia
Edema

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2
Q

Pathology seen in nephrotic syndrome:

Primary versus secondary?

A

Podocyte disruption -> charge barrier impairment.

Primary is direct podocyte damage. Secondary is from systemic process like diabetes.

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3
Q

Three common nephrotic syndrome causing diseases (primary and secondary ___, and two secondary causes___

A

Focal segmental glomerulosclerosis
Minimal Change disease
Membranous nephropathy

Secondary only:
Amyloidosis
Diabetic nephropathy

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