Nephrotic Syndrome

Question 1

what is the triad seen in nephrotic syndrome?

Answer 1

1. proteinuria (>3g/24hr)
2. hypoalbuminaemia (<30g/L)
3. oedema

Question 2

name some nephrotic syndromes

Answer 2

• minimal change disease
• membranous GN
• focal segmental glomerulosclerosis
• amyloidosis
• diabetic nephropathy

Question 3

what is a recognised complication of nephrotic syndrome?

Answer 3

increased risk of venous thromboembolic disease

loss of antithrombin-III, protein C and S and an associated rise in fibrinogen levels