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Word associations: Renal > Nephrotic and nephritic syndromes > Flashcards

Nephrotic and nephritic syndromes Flashcards

1
Q

Characteristics of nephrotic syndrome

A 
>3.5g proteinuria
hypoalbuminemia
edema
hyperlipidema
lipiduria
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2
Q

Characteristics of nephritic syndrome

A 
Decreased renal function
hypertenaion
RBC and RBC casts
Edema
Proteinuria <3.5g/day
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3
Q

Periorbital edema

A

nephrotic syndrome.

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4
Q

Maltese crosses on urinalysis

A

lipiduria characteristic of nephrotic syndrome . “Refractile bodies”

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5
Q

Associated with a hyper coagulable state because of increased coagulation factors, increased platelet aggregation, and decreased ATIII

A

nephrotic syndrome

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6
Q

Increased risk for bacterial infections

A

nephrotic syndrome-loss of immunoglobulins and complement components

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7
Q

Normal renal function with 4+ protein on urinalysis and hyaline casts

A

Minimal change disease (nephrotic syndrome)

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8
Q

Peak incidence 2-6 years old, preference for males

A

Minimal change disease, nephrotic syndrome

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9
Q

History of allergy
Hodgkins lymphoma
NSAIDs

A

Minimal Change Disease (a nephrotic syndrome)

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10
Q

Normal light microscopy
negative IF
EM showing foot process fusion

A

minimal change disease (a nephrotic syndrome

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11
Q

Podocytes strangely expressing CD 80

A

Minimal change disease (a nephrotic syndrome)

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12
Q

Common in young adults (2-40) and African Americans

A

FSGS

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13
Q

suPAR

A

FSGS

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14
Q

Nephrotic syndrome that presents with proteinuria and hypertension. Urinary sediment often has RBCs

A

FSGS

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15
Q

Nephrotic syndrome associated with heroin usage

A

FSGS

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16
Q

Nephrotic syndrome associated with HIV

A

FSGS

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17
Q

nephrotic syndrome that can be idiopathic or related to minimal change disease

A

FSGS

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18
Q

Collapsing focal and segmental glomerulosclerosis
tubular dilation microcysts
reticuloendothelial inclusions

A

HIV nephropathy related to FSGS

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19
Q

APO lipoprotein L1 is the pathological factor

A

FSGS

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20
Q

Antibodies to phospholipase A2 on the podocyte

A

Membranous nephopathy

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21
Q

Related to gold and mercury drugs

A

Membranous nephopathy

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22
Q

Solid malignancies/carcinoma (breast, lung, GI tract, renal)

A

Membranous nephopathy

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23
Q

Immune deposits in the capillary

A

Membranous nephopathy

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24
Q

The following tests:

  • CBC
  • CXR, mammogram, stool test for occult blood, -sigmoidoscopy

Should be performed if this disease is suspected

A

Membranous nephopathy

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25
Chronic HBsAG carriers | responds to interferon
Membranous nephopathy
26
HCV
Type I MPGN
27
Low C3 Low c4 Cryos elevated LFTs
HCV-associated MPGN type 1
28
Low C3 | Low C4
MPGN type I
29
Low C3 | Normla C4
MPGN type II
30
HG/Pb
Membranous nephropathy
31
amyloidosis
plasma cell myeloma
32
lymphoma
Minimal change disease
33
Pulmonary renal syndrome (pulmonary hemorrhage)
Goodpasture's | ANCA vasculitis
34
14-21 days after a GAS infection
post-infectious glomerulonephritis
35
14-21 days after staphylococcus endocarditis
post-infectious glomerulonephritis
36
infected vascular prostheses abscesses or empyema ventricolatrial shunts
Post-infectious glomerulonephritis
37
Antibody to strep antigens resulting in circulating immune complexes
post-infectious glomerulonephritis
38
Light microscopy shows proliferative and exudative GN with infiltration of neutrophils and monocytes
post-infectious glomerulonephritis
39
IF shows granular deposits of IgG and C3 in sub endothelial, mesangial and subepithelieal locations
post-infectious glomerulonephritis
40
EM shows "sub epithelial humps"
post-infectious glomerulonephritis
41
elevated ASO titer
post-infectious glomerulonephritis
42
IgA immune deposits in mesangium
IgA nephropathy
43
Light microscopy: increase in mesangial cell number and matrix
IgA nephropathy
44
EM: mesangial immune deposits
IgA nephropathy
45
asymptomatic hematuria/microhematuria nonnephrotic hematuria nml renal function
IgA nephropathy
46
Occurs immediately with the onset of viral illness
IgA nephropathy
47
Skin biopsy shows IgA
Henoch-Schonlein purpura
48
pupura on arms and legs
Henoch-Schonlein purpura, systemic IgA nephropathy
49
Histological pattern of proliferation (lobular) and thickening of the GBM
MPGN
50
Hep C Cryos RF low complement
MPGN
51
Iron deficient anemia
Goodpasture's or ANCA associated vasculitis
52
ANCA
pauci0immune small vessel vasculitis
53
IF demonstrates "full house" C3, IgG, IgM, IgA, and C1qCryoglobulinemic glomerulonephritis
Lupus nephritis
54
Palpable purpura, arthralgias, generalized weakness
cryoglobulinemia
55
``` Skin lesions (palpable purpura), arthritis, GI involvement (colic and bleeding), GN Kid ```
HSP
56
focal proliferative necrotizing glomerulonephritis, often with crescents
HSP
57
SLE is associated most commonly with which type of Glomerulonephopathy?
membranous
58
Triad of nephritis, deafness, ocular lesions
Alport's Disease
59
Basket weave pattern on electron microscopy
Alport's disease
60
tubuloreticular body in endothelium
SLE nephritis
61
Hyaline arteriolar disease
DM
62
-Medial and intimal thickening | – Hyaline deposition
HTN in renal disease
63
fibrinoid necrosis and hyperplastic arteriolitis
malignant hypertension manifested in the kidney
64
* Pericarditis,pleuritis * Nausea,vomiting, ulcers * Neurologic: itching, seizures, lethargy, coma • Depressed immune response (infections) * Platelet dysfunction (bleeding disorders) * Amenorrhea
uremia
65
Eosins on a UA
AIN (a type of renal/intrinsic AKI)
66
BUN/Cr>20
pre renal azotemia
67
specific gravity > 1.010
pre renal azotemia
68
specific gravity =1.010 but the kidney is injured
ATN
69
FENa <1
pre renal azotemia (or rhabdomyolysis or radiocontrast-not prerenal)
70
FENa >2%
Either intrinsic renal AKI or port renal AKI
71
isosomotic urine in AKI
Intrinsic renal
72
High Uosm in AKI (>500)
pre renal azotemia
73
Pigmented, coarsely granular casts on UA
ATN
74
Renal tubular epithelial cells (RTEs) on a UA
ATN
75
AKI: cardiac dysfunction, edema, rales, S3 gallop
pre renal azotemia
76
Evidence of fever or rash after ampicillin
AIN
77
AKI: intravascular volume depletion (decreased weight, flat neck veins, postural changes in BP/pulse
Pre renal azotemia
78
anuria or swings in urine flow rate
post renal obstruction
79
"Starry sky appearance"
post-infectiousl glomerulonephritis

Word associations: Renal (1 decks)

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