Nephrology Flashcards
What is the pH for measuring acidemia or alkalemia
7.4
What is the CO2 content of the body?
40
Anion gap formula? Normal?
Na-Cl-bicarb; 12 is normal
Why do you always calculate anion gap?
Always check it because if you have an increased anion gap acidosis then you always have anion gap acidosis nomatter what else is going on
What do you do after you identiy a respiratory acidosis?
- 7.4 - (dimes x 0.08) = pH if acute
- 7.4 - (dimes x 0.04) = pH if chronic
What do you do after you after you figure out if the acidosis is acute or chronic?
- 24+ (dimes*1) = expected bicarb if acute
- 24 + (dimes x 3) = expected bicarb if chronic
What do you do after determining that there is a respiratory alkalosis?
Dime changes in CO2 to determine chronicity
- 7.4 - (dimes x 0.08) = pH if acute
- 7.4 - (dimes x 0.04) = pH if chronic
What do you do after determining the chronicity of a respiratory alkalosis?
Dime changes in CO2
- 24-(dimes x 2) = Expected bicarb if acute
- 24-(dimes x 4) = expected bicarb if chronic
What do you do after checking the anion gap in metabolic acidosis?
Expected CO2 using winters formula
- Expected CO2 = Winters = (Bicarb x 1.5) + 8 +/- 2
What do you do after doing winters formula in metabolic acidosis?
Add back method
- Current anion gap - normal anion gap = x
- X + current bicarbs = needed value
- If this value is over 24 = metabolic alkalosis
- If this value is under 24 then there is a metabolic acidosis
Causes of anion gap acidosis?
MUDPILES
- Methanol
- Uremia
- DKA
- Propylene
- Iron
- Lactic acidosis
- Ethylene glycol
- Salicylates
What are the causes of Non gap acidosis?
RTA or diarrhea depending on the urine anion gap
What is the normal urine chloride?
10
What is volume responsive metabolic alk?
- Diuretics, dehydration, emesis, NG suction
- Cl under 10 (because tubes can reabsorb Cl)
UCl > 10 and HTN is caused by
Inappropriate aldosterone