Nephrology Flashcards

1
Q

Section 1 - Acid-base disturbances

A

skip

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2
Q

define Acidemia

A

pH < 7.36

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3
Q

define Alkalemia

A

pH > 7.44

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4
Q

define Acidosis

A

process that increases [H+]

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5
Q

define Alkalosis

A

process that decreases [H+]

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6
Q

define Respiratory compensation

A

Hyper or Hypo-ventilation that alters PaCO2 to counteract the 1* metabolic process
Minutes

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7
Q

define Renal compensation

A

excretion or retention of H+/HCO3- to counteract 1* respiratory process
Hours to days

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8
Q

Does compensation ever fully correct the pH?

A

never

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9
Q

if pH is normal, then what acid/base disturbance should you consider?

A

Mixed disorder

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10
Q

If patient is Acidemic with pH < 7.20, what cardiovascular complications can one expect?

A
decrease contractility
arteriolar vasodilation
decreased MAP and CO
decrease response to catecholamines
increase risk for arrhythmias
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11
Q

If patient is Acidemic with pH < 7.20, what respiratory complications can one expect?

A

Hyperventilation

decreased resp muscle strength

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12
Q

If patient is Acidemic with pH < 7.20, what metabolic complications can one expect?

A

increased K+

Insulin Resistance

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13
Q

If patient is Acidemic with pH < 7.20, what neurologic complications can one expect?

A

change in mentation

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14
Q

If patient is Alkalemic with pH > 7.60, what cardiovascular complications can one expect?

A

Arteriolar vasoconstriction
decreased Coronary Q
increase risk of arrhythmias

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15
Q

If patient is Alkalemic with pH > 7.60, what respiratory complications can one expect?

A

Hypoventilation

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16
Q

If patient is Alkalemic with pH > 7.60, what metabolic complications can one expect?

A

decreased K+, iCa++, Mg++, PO4

17
Q

If patient is Alkalemic with pH > 7.60, what neurologic complications can one expect?

A

altered mental status
seizures
tetany (hypocalcemia?)

18
Q

Work-up of a/b disorder?

A

determine Primary disorder – check pH, PaCO2, HCO3-

determine if degree of compensation is appropriate