Nephro

Question 1

normal GFR

Answer 1

men: 127
women: 118

Question 2

name endogenous chemicals and drugs that affect afferent/efferent arterioles

Answer 2

ACE I: dilate efferent
NSAID: constrict afferent
Ang II: constrict efferent
PGE: dilate afferent

Question 3

Cockroft Gault equation

Answer 3

CrCl = (140-age) * weight * 0.85 (if female) // 72 * SCr

Question 4

what size protein can pass through membran

Answer 4

< 5 kda

Question 5

what size protein can’t pass through membrane

Answer 5

> 60 kda

Question 6

what charge is the membrane?

Answer 6

negative

Question 7

what charge cannot pass through membrane?

Answer 7

negative

Question 8

normal values of GFR?

Answer 8

men 127

women 118

Question 9

which one is afferent?

Answer 9

the one that goes in

Question 10

efferent?

Answer 10

the one that goes out

Question 11

initiation factors

Answer 11

DM, HTN, GN

Question 12

what is the difference between susceptibility, initiation, and progression factors

Answer 12

susceptibility: things you can’t control
initiation: diseases you can manage
progression: if you don’t fix initiation factors

Question 13

Hendersen Hasselbach equation

Answer 13

pH = 6.1 + log (bicarb/PCO2*0.03)

Question 14

metabolic acidosis causes

Answer 14

anion gap
diarrhea
dichloroacetate because lactate is made
chloride because they switch
renal tubular acidosis

Question 15

types of renal tubular acidosis

Answer 15

I) distal hypo
II) proximal
III) both
IV) distal hyper

Question 16

non selective alpha antag

Answer 16

doxazosin
prazosin
terazosin

Question 17

uroselective alpha antag

Answer 17

alfazosin
silodosin
tamsulosin

Question 18

PDE inhibitor for BPH

Answer 18

tadalafil

Question 19

5 alpha reductase drugs

Answer 19

finasteride, dutasteride

Question 20

brand

Answer 20

generic

Question 21

size of prostate

Answer 21

small is < 40g

Question 22

which alpha antag QT prolongation

Answer 22

alfuzosin