NeoTypes

Question 1

Name all cancer specific NeoType profiles offered for heme patients? (hint: 12 total)

Answer 1

ALL, CLL Prognostic, AML Prognostic, Lymphoma, AITL/Peripheral T-Cell Lymphoma, Follicular Lymphoma, JMML, MDS/CMML, Myeloid Disorders,

Question 2

Name all cancer specific NeoType profiles offered fir solid tumor? (hint: 19 total)

Answer 2

Gastric, GI Predicitve, Liposarcoma, Thyroid, Melanoma, Esophageal, Cervical, Liver/Billiary, Other Solid Tumor, Pancreas, Lung, Colorectal, Endometrial, Brain, Breast, Head & Neck, Ovarian, GIST/Soft Tissue, Cholangiocarcinoma,

Question 3

When would someone use NeoType HRD+ Profile?

Answer 3

Most commonly used for prostate cancer, but can also be used for any other type of cancer when only HRD genes are important to OP

Question 4

What is the TAT for NeoTypes?

Answer 4

14 days

Question 5

Name all of Neo’s pan cancer solid tumor profiles?

Answer 5

Precision and Discovery

Question 6

Does Neo offer any Pan-Cancer Profiles for Heme patients?

Answer 6

Yes - Discovery Profile

Question 7

What are the specimen requirements for the heme Neotypes?

Answer 7

Bone Marrow (2mL EDTA Tube)
Peripheral Blood (5mL EDTA Tube)
FFPE Tissue (paraffin block or 1 H&E slide and 5-10 unstained slides) - positively charged slides & 10% NBF fixative (no zinc or mercury fixatives)

Question 8

What are the specimen requirements for solid tumor neotypes?

Answer 8

FFPE Tissue: Paragin block using 10% buffered formalin and no zinc fixatives

Question 9

How are NeoType results reported to OP’s?

Answer 9

For each methodology completed, a preliminary report will be issued. When all testing is completed, a final cumulative report will be sent.

Question 10

What methodologies are usually used in NeoTypes?

Answer 10

IHC, NGS and FISH

Question 11

What levels of service are offered for NeoTypes?

Answer 11

Global and TC for IHC and FISH

Question 12

What components are included in every NeoType report?

Answer 12

Diagnostic, Prognostic, Therapeutic and Clinical Trial Information

Question 13

Which NeoTypes are on Neo’s Non-Covered List?

Answer 13

AITL/Peripheral T-Cell Lymphoma, CLL Prognostic, HRD+, and Liposarcoma

Question 14

Which NeoTypes offer Tumor Mutation Burden (TMB) Testing?

Answer 14

All solid tumor NeoTypes