Neoplasms Flashcards
1
Q
SCLC
A
- mets rapidly to regional LN & distant sites
- very responsive to chemo
- remission and recurrence common (survival 5%)
2
Q
Lung CA likely to cz paraneoplastic syndromes like:
A
hyperCa, SIADH, ectopic ACTH secretion, Lambert-Eaton myasthenic synd (autoimmune, MSK), hypercoag states
3
Q
Lung CA s/s
A
- hoarseness from recurrent layngeal nerve compression
- facial or UE swelling from SVC synd
- alarm sx
4
Q
Lung CA mets locations
A
- bone, brain, liver, adrenal
- axillary/supraclavicular LAD
5
Q
lung CA ddx
A
TB, fungal inf, mets TO lung, sarcoidosis
6
Q
lung CA wu
A
- CXR
- fu w/ CT
- sputum cytology
- bronchoscopy
- transthoracic needle bx
- node sampling via transbronchial bx, mediastinoscopy/tomy
7
Q
lung CA tx
A
- assess surg poss
- rad for adv dz & nonsurg candidates
- combo chemo
- monitor for recurrence
8
Q
NSCLC
A
- discrete masses w/in lung parenchyma
- spread to reg LN then mets to distant sites
- limited resp to chemo
- surg resect of limited tumors
- staged by TNM
9
Q
SCC (lung)
A
assoc w/ slow growth & late mets
10
Q
Bronchial Carcinoid Tumor
A
- aka bronchial adenoma
- rare
- can be in thymus, GI tract, ovaries
- Tx of choice = surg resect
11
Q
adenocarcinoma (lung)
A
- peripheral
- rapid growth w/ mets
- assoc w/ lung scarring, NOT smoking
12
Q
pulm nodules
A
- < 3 cm, solitary = less likely CA
- < 5% chance of CA: watch (< 30 y.o., lesions stable x 2 yrs, b9 calcification pattern)
- intermediate chance of CA: ref for TTNA, bronchoscopy, PET, VATS
- > 60% chance of CA: ref for staging and excision
13
Q
pulm nodule wu:
A
- fu CXR w/ CT
- CA clues: spicules, peripheral halo, or eccentric calcification on CT, cavitary lesions w/ thick walls
- b9 clues: doubling > 1 yr, central calcification on CT
14
Q
multiple pulm nodules ddx
A
mets, bronchogenic CA, TB, abscess, sarcoidosis, pneumoconiosis, Wegener’s granulomatosis (blood vess inflam), methotrexate use
