Neoplasms Flashcards

1
Q

Which one of the following tumours never metastasises

Malignant melanoma
Small cell carcinoma of the lung
Basal cell carcinoma of the skin
Breast cancer

A

Basal cell carcinoma of the skin

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2
Q

What’s the name of the malignant tumour of striated muscle

A

rhabdomyosarcoma

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3
Q

Which of the following tumours does not commonly metastasise to the bone?

Breast cancer
Lung cancer
Prostate cancer
Liposarcoma

A

Liposarcoma

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4
Q

What term describes cancer that has not invaded through the basement membrane

A

Carcinoma in situ

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5
Q

What is the name of a benign tumour of glandular epithelium?

A

adenoma

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6
Q

Which one of these tumours do not have a screening programme in the UK

Breast Cancer
Colorectal Cancer
Cervical Cancer
Lung Cancer

A

Lung Cancer

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7
Q

Which one of the following is not known to be a carcinogen in humans

Hepatitis C
ionising radiation
Aromatic amines
Aspergillus niger

A

Aspergillus niger

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8
Q

What is the name of a benign tumour of fat cells

A

Lipoma

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9
Q

Which one of the following is not a feature of malignant tumours

A.Vascular invasion
B.Metastasis
C.Increased cell division
D.Growth related to overall body growth

A

D.Growth related to overall body growth

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10
Q

Is transitional cell carcinoma of the bladder a malignant tumour?
True or False

A

True

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11
Q

A leiomyoma is a benign tumour of smooth muscle

A

True

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12
Q

Radon gas is a cause of lung cancer

A

True

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13
Q

Asbestos is a human carcinogen

A

True

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14
Q

Which lifestyle factor is most likely to cause cancer

Drinking half a bottle of wine a day
Being obese
Running for 20mins twice a week
Smoking 20 cigarettes a day

A

Smoking 20 cigarettes a day

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15
Q

Which tumour has the shortest median survival

Basal cell carcinoma of the skin
Malignant melanoma of the skin
Breast Cancer
Anaplastic carcinoma of the thyroid

A

Anaplastic carcinoma of the thyroid

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16
Q

Ovarian cancer commonly spreads in the peritoneum

A

True

17
Q

A 27-year-old woman presents to the A & E department with abdominal pain. She says that it started the day before when she felt rather fitful and woke up this morning with a more severe pain that had moved other right groin region. A diagnosis of acute appendicitis is made, and her appendix is removed during a laparoscopic operation. The appendix is sent to the Department of Histopathology, where it is sampled, and microscopic slides are produced. The Consultant Histopathologist looks at the lumen of the appendix with a high-power lens on her microscope.

What is the predominant type of inflammatory cell that she sees?
a. Eosinophil
b.Lymphocytes
c.Macrophage
d. Mast cell
e. Neutrophil polymorph

A

e. Neutrophil polymorph

18
Q

A 25-year-old lawyer falls on the ski slopes, and after being taken off the slopes on a stretcher, a radiograph shows a depressed fracture of the tibia. During an operation, the depression is elevated and internally fixed, and the leg is immobilised in plaster. After 6 weeks, the plaster is taken off. The patient notices that the leg which had the fracture appeared to be much thinner than the other leg

If a biopsy was taken (not clinically indicated in this case) from the quadriceps muscle of the affected leg what would it show?

a. Atrophy
b. Hyperplasia
c. Hypertrophy
d. Metaplasia
e. Dysplasia

A

a. atrophy

19
Q

A 43-year-old woman is referred to a gynaecologist with a history of pain during sexual intercourse and vaginal bleeding after intercourse and in between her periods. The gynaecologist takes an ectocervix biopsy, revealing a primary malignant neoplasm.

What is the likely diagnosis?

A

Squamous cell carcinoma

20
Q

A histopathologist is examining the biopsy taken from the patient’s ectocervix.

Which of the following is a feature of malignant epithelial neoplasms but not of benign epithelial neoplasms?

Encapsulation
Exophytic growth
Low mitotic activity
Normal nuclear morphometry
Ulceration

A

Ulceration

21
Q

A 46-year-old woman undergoes an elective hysterectomy to treat severe menorrhagia (heavy periods). The pathologist examining the specimen reports the presence of multiple benign smooth muscle neoplasms within the myometrium.

What are these neoplasms called?
Leiomyomas
Leiomyosarcomas
Liposarcomas
Rhabdomyomas
Rhabdomyosarcomas

A

Leiomyosarcomas