Neoplasia Flashcards
What is Cancer?
group of diseases defined by uncontrolled proliferation, it is genetic (somatic mostly, and germ-line)
it originates from one single cell
problem with the cell
ability to undergo self renewal and lose the ability to fully differentiate
3 embryonic germ layers
ectoderm (external layer) mesoderm (middle layer) Endoderm (internal layer)
hypertrophy
increase in individual cell size not number
hyperplasia
increase in cell number with intact cell cycle regulations and within the anatomic boundaries
dysplasia
disorderly arrangement or differentiation of cells
metaplasia
transformation of one differentiated cell type to another
ex: most common - columnar epithelium become stratified squamous metaplasia
smoking
tumor nomenclature need
cell of origin
classification of tumors
embryonic origin, cell of origin,
Epithelial means
skin, mucosa, glandular tissues
Mesenchymal: mesoderm
bone, cartilage, muscle, endothelium, CT
Hematopoietic
lymphoma, leukemia
Neurocetodermal
CNS tumors
benign tumor: epithelial
cell type + adenoma or oma and may have descriptions
malignant tumor: epithelial
cell type + carcinoma or adenocarcinoma and may have description