neoplasia Flashcards

1
Q

neoplasm

A

“new growth”
A neoplasm is an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissue and persists in the same excessive manner after cessation of the stimuli that caused the change.
cancer=result of malignant neoplasms

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2
Q

malignant tumor names

A
Malignant tumors that arise from mesenchymal tissue are usually called sarcomas:
fibrosarcoma - fibrous tissue
liposarcoma - fat tissue
leiomyosarcoma - smooth muscle
rhabdomyosarcoma - striated muscle

Malignant tumors that arise from epithelial cell origin (three germ layers) are called carcinomas:
Adenocarcinomas - glandular origin
Squamous cell carcinomas - from epithelium

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3
Q

cystic teratoma of ovary

A

the presence of hair, sebaceous material, and tooth. contains parenchymal cells from all 3 germ layers (skin, sebaceous gland and cartilage)

tetratoma=benign=round margins
common in kids

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4
Q

malignant?

A
if metastases are present, it is malignant! 
invasive borders (not smooth) 

other factors:
Differentiation (extent to which parenchymal cells resemble normal cells) and Anaplasia (doesn’t look like anything
Rate of growth
Local invasion

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5
Q

METAPLASIA

A

a REVERSIBLE change in which one adult cell type ( epithelial or mesenchymal ) is replaced by another adult cell type.

like superman (benign to benign) ==> not malignant

can happen anywhere in the body

benign and reversible

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6
Q

DYSPLASIA

A

deranged development. Proliferation and atypical cytologic alterations involving cell size, shape, and organization.

premalignant–> changes in cells genetic and controllable nature. autonomous growth
should be removed

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7
Q

Carcinoma-in-situ

A

Malignancy present in cell tissue of origin

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8
Q

Pleomorphism

A

variation in size & shape

Degree of pleomorphism ~ degree of anaplasia/ malignancy

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