neoplasia 1 Flashcards
define tumor
swelling or growth.
define neoplasm
abnormal mass, growth exceeds & uncoordinated w normal tissue.
persists after cessation of stimuli.
genetic alteraction passed down
define benign
neoplasm that reamins localized. generally patient survives, generally surgery = treatment.
sometimes can metastasize, can also cause problem in organ its invading
define malignant
invades and destroys adjacent structures.
ability to metastasize, ability to cause death. usually lobulated.
define cancer
generic term for neoplasm
ectoderm - in embryo , what structures does it produce?
epidermis, CNS, bone & muscle in head and neck
endoderm - what structures in adult?
GI, thymus, parathymus
mesoderm - what structures in adults?
bone, skeletal muscle, kidney, heart
two factors of influence for naming tumors
- tissue of origin (epithelial, mesenchymal [connective, endothelium, muscle, blood], melanocyte, mixed)
- malignant potential (benign, malignant)
naming benign neoplasms. suffix
"oma" Mesenchymal: fibrous = fibroma cartilage = chondroma smooth = leiomyoma skeletal = rhabdomyoma bone: osteoma epithelial : adenoma - from glands papilloma - finger-like warty projection. cystadenomas melanocytic = nevi / moles exceptions to -oma rule. melanoma, lymphoma, mesothelioma, teratoma (maturation determines malignant potential)
exceptions to -oma (benign) rules
mesothelioma
melanoma
lymphoma
teratoma
teratoma - malignant potential?
mature cystic teratoma
–females = composed of all 3 germ layers. benign.
males - mixed germ layer of tests = malignant
immature = malignant.
malignant neoplasms -
mesodermal:
sarcoma (mesoderm, except head and neck)
lymphoma/leukemia: blood/lymph node neoplasm
carcinoma = epithelial neoplasm. (endo and ectoderm)
melanoma- melanocytic neoplasm
naming.
mesenchymal
epithelial
Mes: end with sarcoma. fibrosarcoma
skeletal muscle = rhabdomyosarcoma
fibrous tissue name benign & malignant
fibroma
fibrosarcoma