Neonatal

Question 1

transient neonatal pustular melanosis

Answer 1

onset at birth in darkly pigmented infants

sterile subcorneal pustules with NEUTs

Question 2

erythema toxicum neonatorum

Answer 2

onset 24-48 hrs after birth

sterile subcorneal pustules with EOS associated with pilosebaceous unit

Question 3

neonatal acne (neonatal cephalic pustulosis)

Answer 3

onset within 30 days
Malassezia
comedomes, papules, pustules
follicular pustules with neuts

Question 4

sclerema neonatorum presentation? association? histo?

Answer 4

onest first wk
panniculitis in severely ill premature infants
diffuse woody hardening of skin sparing genitalia, palms/soles
histo: needle-shaped clefts with necrotic adipocytes and no inflammation

Question 5

subcutaneous fat necrosis of the newborn presentation? what lab to monitor? histo?

Answer 5

onset first weeks
localized sclerema neonatorum in healthy infants
indurated subcu nodules of cheeks, buttocks, shoulders and thighs
assoc w/ hypothermia, perinatal hypoxemia, hypoglycemia
**monitor calcium levels (hypercalcification –> calcification)
histo: panniculitis with inflammatory infiltrate, needle-shaped clefts and fat necrosis

Question 6

aplasia cutis congenita presentation? 3 associations?

Answer 6

onset before birth
erosion, ulceration, scar or membranous defect
hair collar sign
may be marker of neural tube defect
assoc w/ Bart syndrome, Adams-Oliver syndrome, Seitles syndrome

Question 7

Bart Syndrome

Answer 7

aplasia cutis congenita of LEs + epidermolysis bullosa

Question 8

Adams-Oliver Syndrome

Answer 8

aplasia cutis congenita of scalp with ossification defect + cutis marmorata telangiectatic congenita & limb defects + cardiac abnormalities

Question 9

Seitles syndrome

Answer 9

b/l temporal aplasia cutis congenita + abnormal eyelashes + leonine faces & upward slanting eyebrows

Question 10

cutis marmorata telangiectatica congenita

Answer 10

onset at birth, improves with age

blanching reticulated vascular pattern on trunk/extremities with segmental distribution

Question 11

cadidal diaper dermatitis

Answer 11

bright red patches w/ pustules & satellite papules
+intertriginous
+scrotum
+/-thrush

Question 12

irritant diaper derm

Answer 12

poorly demarcated plaques

spares inguinal folds

Question 13

seb derm diaper derm

Answer 13

salmon-colored scaly patches and plaques

scalp, groin, intertriginous

Question 14

psoriasis in diaper distribution

Answer 14

sharply demarcated bright pink-red
inguinal creases involved
minimal scale
MC location in infants

Question 15

granuloma gluteale infantum

Answer 15

red-violaceous granulomatous nodules
vulva, perianal, buttock, scrotum
due to irritation/occlusion/candida