Neo/peds Flashcards
Normal pulse
130-160
Normal respiratory rate
40-60
Ductus venosus
Allows blood to go from the umbilical vein, bypass the liver and connect to the IVC short cut to inferior vena cava
Foramen Ovale
Opening between the atria
Ductus arteriosus
the connection between the pulmonary artery and arota
Deceleration
- temporary decrease in fetal HR during contraction
- decrease of 15-45 beats/min is considered a decel
- early deceleration in relation to contractions is normal
- late or variable declaration may indicate fetal stress and is often related to reduced blood flow
What does the Silverman score assess?
assess respiratory distress, work of breathing
What does the Ballard score assess?
estimate the gestation age
best 0, worst 10
At what HR do i start PPV? Compressions?
HR <100: PPV
HR <60: Compressions
What changes result in the closure of the fetal anatomic shunts?
- Pulmonary vascular resistance decreases
- systemic vascular resistance increases
How many grams in 1 pound?
454 gm
Acrocyanosis
cyanosis of the hands/feet
What is Pallor?
- ashin/grey color
- indicates blood loss
- shock
- blood redistribution
What is central cyanosis?
- Cyanosis on all perfused surfaces
- R to L shunting
- Congenital heart disease
- persistent fetal circulation
- pulmonary/RDS
- CNS distrubances
What are the goals of oxygen therapy in neonates?
- Treat hypoxemia
- <32 wk: 88-92%
- >32 wk: 90-95%
What are some hazards of O2?
ROP
BPD
What is Retinopathy of Prematurity(ROP)?
- Loss of vision
- immature retinal vasculature constricts in response to elevated O2 tension
What is bronchopulmonary dysplasia (BPD)?
- Chronic lung disease associated with high levels of O2 and mechanical ventilation for an extended time
What is a Neutral thermal environment?
- allows neonates to maintain normal internal temperature without increased O2 consumption
- neonates have a large body surface area to mass ratio causing them to loss heat fast
Indications for CPAP
- Refractory hypoxemia
- obstructive apnea- stabilize soft tissue to relieve obstruction
- Central apnea- can stimulate respiration in some infants
What is the process for the initiation and application of CPAP?
- start at setting 4-5 cmH2O
- use same FiO2 from device they were moved fro,
- increase CPAP in increments of 2-3 cmH2O per dr. order
- flow range from 5-10 LPM
- Max of 12cmH2O (10 is high)
try to maintain adequate PaO2 mmHg with FiO2 of 0.5 or less
How can we reach an NTE?
Incubator or warming lights
What are the advantages of Pressure control?
- Infants use cuffless tubes which would cause volume loss if using VC
- able to regulate peak pressure and decrease the risk of barotraume
- volume loss due to tubing compliance is not an issue
What are the disadvantages of pressure ventilation?
- volume is variable and dependent on changes in the respiratory system mechanics (AKA resistance and compliance)
- Risk of volutrauma
What is pressure control/volume guarantee?
allows for a set volume target while maintaining the pressure control mode. Won’t go full Vt if it hits the max pressure allowed
What are the intial pressure control ventilatory settings for an infant?
PIP
PEEP
Frequency
Itime
Etime
I:E ration
flow rate
FiO2
- PIP: 16-20 (titrate to 4-6ml/kg)
- PEEP: 5 cmH20
- Frequency: 20-40
- Itime: 0.3-0.5 sec
- Etime: 0.6 or greater
- I:E ration: 1:2 or greater
- flow rate: 6-12 LPM
- FiO2: try to keep = 50
What is the target Vt in mechanical ventilation of an infant and pediatric patient?
- Infant: 4-6 ml/kg
- pediatric: 6-8 ml/kg
What is normal compliance in a neonate?
2.5-5 ml/cmH20
Criteria for weaning from mechanical ventilation
- underlying reason for intubation resolved or improved
- vital signs stable
- blood gas acceptable
- spontaneous effort (minimal sedation)
What are some general steps for weaning?
- Decrease O2 by 2 – 5% (to 40 - 50%)
- Decrease PEEP 1 -2 CmH2O (to 3 – 5 cmH2O)
- Decrease PIP 1 – 2 CmH2O (to 15 – 20)
- Decrease rate 1 – 5 (to rate of 10 - 20)
- Extubate to CPAP, HFNC or O2 as required
What setting is commonly used for the pediatric population?
- Volume control because they often have cuffed ETT
- Need to consider volume loss due to circuit compliance
- very important because of small Vt
- set volume may need to be increased to compensate for lost volume if vent doesn’t automatically compensate
What is the formula for volume loss?
to be used in ventilators that do not compensate
vol lost= driving pressure X TCF
driving pressure=PIP=PEEP
What is the formula for Vt?
Vt= flow in L/sec X I-time
What are hazards of mechanical ventilation?
- Oxygen toxicity
- Retinopathy of Prematurity (ROP)
-American Academy of Pediatrics recommends PaO2 < 80 mmHg
- Bronchopulmonary Dysplasia (BPD)
- Barotrauma
- Decreased CO
- Intraventricular hemorrhage (IVH)
- Gastric distention (Use NG tube)
- Infection
- Complications of endotracheal intubation
What is MAP?
- Average pressure exerted on the airway and lungs from the beginning of inspiration until the beginning of next inspiration
- a powerful influence on oxygenation
- high levels (above 12 cmH2O) can lead to decreased cardiac output, pulmonary hypoperfusion and barotrauma
How is a capillary blood gas performed?
- Area is warmed to 42 degrees max to “arterilize” the blood
- alcohol size
- lancet puncture 2mm deep
- collect a sample- do not squeeze site
- fill tube quickly to minimize air exposure
- outside of heel is preferred to avoided nerve damage
What sites are used for an ABG in infants?
- radial
- temporal
- pedal
- umbilical in neonates
- avoid brachial and femoral if possible
What is transcutaneous blood gas monitoring?
- O2 and CO2 diffused through the skin and can be measure to correlate with ABG
- provides continuous monitoring
- electrode warmed to 44 degrees to cause local vasodilation for more “arterialized” results
ETT size by age
- Full term: 3.5-4
- 1 yr.: 4.5
- 4 yr.:5.0
- 8 yr.: 6.0
- 12 yr.: 7.0
- Over 1yr. age/4+4+ ETT ID
What is HFPPV?
- High frequency positive pressure ventilation
- freq: 60-149
What are indications for HFV? High frequency ventilation
- Conventional ventilation inadequate
- lung hypoplasia, PPHN, RDS, MAS
- Maxed PIP, cant increase Vt etc
- Multiple or recurrent pneumothoraces
- persistent Leak!
- upper airway surgery or special procedure laryngoscopy
What changes do I make on HFO to adjust a PaCO2?
- increase amplitude to decrease CO2
- decrease frequency to decrease PaCO2
What pressures are used for suctioning for neonates, peds, and adults?
- Neonates: -60- -80 mmHg
- Peds: -80- -100mmHg
- Adults: -100- - 120 mmHg
Indications of iNO
- Hypoxemic respiratory failure
- PPHN (persistent pulmonary HTN of the newborn)
- CDH (congenital diaphragmatic hernia)
- OI (Oxygenation index) >25
What is the dosing of iNO? and how is it administered? what is the benefit of using NO versus other vasodilators
- 20 ppm (can range from 10-80)
- Administered continuously via vent circuit, nasal cannula, or Ambu bag
- it is a selective vasodilator so it does not cause systemic hypotension
What are some adverse effects of iNO?
- NO2
- pulmonary edema
- lung tissue injury
- rebound pulmonary hypertension and hypoxia with withdrawal
- increase of methemoglobin levels
What is the process of weaning iNO?
- wean dose by half as tolerated
- 20ppm→10→5→2ppm
- FiO2 <= to .40 and PEEP <= 5 cmH2O
- If the above are met and pt stable
- increase FiO2 by .20
- discontinue iNO
How do we assess a patient on HFV?
- Evaluate change by the chest wiggle
- decrease in chest wall vibration or increased PaCO@ and decreased PaO2 could be
- decreased lung compliance (decreases wiggle)
- pneumothorax
What are the indications of ECMO?
- refractor respiratory failure
- cardiac failure
What is the difference between veno-venous ECMO and Veno-arterial ECMO?
- VV
- supports oxygenation and ventilation
- Does NOT support cardiac output
- double-lumen catheter in RA drains and replaces blood
- VA
- oxygenates blood and supports cardiac function and output
- Blood removed from RA via internal jugular
- returned to aortic arch via R carotid artery
What do we do with the ventilator while a patient is on ECMO?
- patient remains intubated and ventilated
- reduced rate
- reduced pressure
- reduced FiO2
- still supply PEEP
What are possible complications of ECMO?
- Emboli (anti-coagulants to help prevent)
- intraventricular hemorrhage (IVH) bleeding
- anemia, leukopenia, thrombocytopenia
- caused by membrane oxygenator
- infection
- mechanical complications
What are advantages of using TCM?
- Non-invasive
- Can detect hyperoxia
- displays TcPo2 and TcPCO2 continuosly
- can detect changes in patient status fast
- way to monitor ventilation and oxygenation
How can oximetry be used to assess pulmonary hypertension?
- uses 2 probes. one placed pre-ductally and one post
- greater than 5-10% difference in SaO2 (post and pre-ductal) is significant for PDA
- indicated pulmonary HTN is present
- ductus arteriosus is not closed between the aorta and pulmonary artery
What is time-based capnography?
- Exhaled CO2 partial pressure measure
- non-invasive continuous trending of CO2
- trends go together but are not the same. They trend
- PECO2 normally 1-5 mmHg lower than PaO2
What is the narrowest portion of a neonate airway vs. an adult airway?
- Neonate: cricoid cartilage
- Adult: vocal cords