neisseria meningitidis

Question 1

n.mening is a

Answer 1

gram negative diplococci

Question 2

ferments what?

( whiskey bottle)

Answer 2

maltose

Question 3

has what type of capsule? and this prevents what

Answer 3

polysaccharide and phagocytosis

Question 4

which causes most of the disease in the US

Answer 4

serotype B

Question 5

which has a poor imunogenic
(bourbin in capsule)

Answer 5

serotype B

Question 6

Expreses what protease

(torn ace card)

Answer 6

IgA protease

Question 7

what is the function of IgA protease

Answer 7

cleave IgA

Question 8

what toxin does this produce
( lost flame)

Answer 8

LOS endotoxin

Question 9

what is the LOS compound function

Answer 9

pro-inflamatory compound

Question 10

what proteins does this batceria have

Answer 10

PorA and PorB

Question 11

what are the functions of porin proteins

Answer 11

control diffusion and interacting with host cells

Question 12

what binding protein is present

Answer 12

Transferrin binding protein

Question 13

does this bacteria have a pili?

Answer 13

yes

Question 14

what is the function of the pili

Answer 14

attachment to host cells and transfer genetic material and motility

Question 15

how is it spread
(man sweating)

Answer 15

respiratory droplets

Question 16

What are the 4 diseases associated with this bacteria

(rolled dice)

Answer 16

meningitist
sepsis
DIC
Waterhouse- Friderichsen syndrome

Question 17

what is DIC

Answer 17

endotoxic shock

Question 18

what is Waterhouse- Friderichsen syndrome

Answer 18

shock with bilateral hemorrhagic destruction of the adrenal glands `

Question 19

what is the port of entry

Answer 19

nasopharynx

Question 20

the bacteria attaches to

Answer 20

cd40 on nonciliated epithelium

Question 21

when is the peak incidence of IMD

Answer 21

6-24 months

Question 22

what type of vaccines

Answer 22

tetravalent conjugated capsular vaccines

Question 23

what are two treatments

Answer 23

penicillin and ceftriaxone