Neisseria Flashcards
what kind of fermentation do neisseria do
aerobic
what kind of bacteria are neisseria
gram neg cocci
what is the arrangements of neisseria
diplococci
what are the oxidase and cat results of neisseria
oxi pos, cat pos
T or F: neisseria are motile
F
are neisseria part of the normal microbiome? if so where
yes; back of throat and genital tract
T or F: pathogenic species of neisseria are fastidious
T
what kind of host can pathogenic neisseria infect
humans only.
what shape is n. meningiditis
meningococci
where in the body does n. meningiditis colonize the body without causing disease
nasopharynx
what kind of media does n. meningiditis grow on
blood agar and chocolate
what kind of sugar does n. meningiditis oxidize
glucose and maltose
what shape is n. gonorrhoeae
gonococci
is n. gonorrhoeae part of the normal microbiome
no
what kind of media does n. gonorrhoeae grow on
chocolate
what are the conditions n. gonorrhoeae grows at (3)
body temp, humid, with 5% CO2
how is n. gonorrhoeae transmitted
sexually
what neisseria has a polysaccharide capsule
n. meningitidis
how is n. meningitidis serogrouped
based on palysaccharide capsule
n. gonorrhoeae has what that acts like a capsule
neg surface charge
do pathogenic or non pathogenic neisseria have pili
both
what do pathogenic strains of neisseria use pili for
attachment, neutrophil killing
what allows pathogenic neisseria to get reinfection
antigenic variation of pilin
what kind of porin protein is on the outer mmb of n gonorrhoeae and n meningiditis
PorB
what is the function of PorB
invasion and protection of bacteria
what is the function of spa proteins
binding and signaling
what is the function of Rmp proteins
non recognition of bacteria surface proteins
does n. meningidis or gonohoerea have more bacterial surface receptors
gonococci
what is an LOS
short sugar on the outer mmb of neisseria
what kind of toxin does the LOS act like
endotoxin
what coats the outer mmb blebs
LOS
what does n. meningiditis and n. gonorrhoeae produce that chops up abs
A1 protase
what does gonococcal LOS stimulate the release of
tumor necrosis factor alpha
who are usually the asymptomatic carriers of n. gonorrhoeae
women
gonorrhea in men is the infection in the ___
urethra
gonorrhea in women is the infection in the ___
cervix
what can a gonorrhea infection in women lead to
pelvic inflammatory disease
def? n. gonorrhoeae infection in the skin and joints with septicemia
gonococcemia
who is more likely to get gonococcemia
women
what is the main symptom of gonococcemia
septic arthritis
what is the eye infection of n. gonorrhoeae called
purulent conjuctivitis
what is the anal infection of n. gonorrhoeae called
anorectal gonorrhea
what is the throat infection of n. gonorrhoeae called
pharyngitis
where are the n. meningtidis epidemic
developing countries
where is the meningitis belt
africa
how is n. meningitidis spread
respiratory droplets by prolonged close contact
what is the likely disease? child with fever and vomiting with neck stiffness
meningitis
what is the likely disease? skin lesion is meningeal signs
meningococcemia
if n. meningitidis gets into the respiratory tract what does it cause
pneumonia
how is neisseria diagnosed in the lab (3)
gram stain, PCR, and culture
if someone has a asymptotic neisseria infection is a gram stain a good way to diagnosis
no
is there a vaccine for n. gonorhoeae
no
is there a vaccine for n. meningitidis? if so who
yes 2 only for teens and elderly.
