Neisseria Flashcards

1
Q

what kind of fermentation do neisseria do

A

aerobic

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2
Q

what kind of bacteria are neisseria

A

gram neg cocci

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3
Q

what is the arrangements of neisseria

A

diplococci

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4
Q

what are the oxidase and cat results of neisseria

A

oxi pos, cat pos

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5
Q

T or F: neisseria are motile

A

F

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6
Q

are neisseria part of the normal microbiome? if so where

A

yes; back of throat and genital tract

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7
Q

T or F: pathogenic species of neisseria are fastidious

A

T

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8
Q

what kind of host can pathogenic neisseria infect

A

humans only.

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9
Q

what shape is n. meningiditis

A

meningococci

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10
Q

where in the body does n. meningiditis colonize the body without causing disease

A

nasopharynx

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11
Q

what kind of media does n. meningiditis grow on

A

blood agar and chocolate

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12
Q

what kind of sugar does n. meningiditis oxidize

A

glucose and maltose

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13
Q

what shape is n. gonorrhoeae

A

gonococci

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14
Q

is n. gonorrhoeae part of the normal microbiome

A

no

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15
Q

what kind of media does n. gonorrhoeae grow on

A

chocolate

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16
Q

what are the conditions n. gonorrhoeae grows at (3)

A

body temp, humid, with 5% CO2

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17
Q

how is n. gonorrhoeae transmitted

A

sexually

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18
Q

what neisseria has a polysaccharide capsule

A

n. meningitidis

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19
Q

how is n. meningitidis serogrouped

A

based on palysaccharide capsule

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20
Q

n. gonorrhoeae has what that acts like a capsule

A

neg surface charge

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21
Q

do pathogenic or non pathogenic neisseria have pili

A

both

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22
Q

what do pathogenic strains of neisseria use pili for

A

attachment, neutrophil killing

23
Q

what allows pathogenic neisseria to get reinfection

A

antigenic variation of pilin

24
Q

what kind of porin protein is on the outer mmb of n gonorrhoeae and n meningiditis

A

PorB

25
Q

what is the function of PorB

A

invasion and protection of bacteria

26
Q

what is the function of spa proteins

A

binding and signaling

27
Q

what is the function of Rmp proteins

A

non recognition of bacteria surface proteins

28
Q

does n. meningidis or gonohoerea have more bacterial surface receptors

A

gonococci

29
Q

what is an LOS

A

short sugar on the outer mmb of neisseria

30
Q

what kind of toxin does the LOS act like

A

endotoxin

31
Q

what coats the outer mmb blebs

A

LOS

32
Q

what does n. meningiditis and n. gonorrhoeae produce that chops up abs

A

A1 protase

33
Q

what does gonococcal LOS stimulate the release of

A

tumor necrosis factor alpha

34
Q

who are usually the asymptomatic carriers of n. gonorrhoeae

A

women

35
Q

gonorrhea in men is the infection in the ___

A

urethra

36
Q

gonorrhea in women is the infection in the ___

A

cervix

37
Q

what can a gonorrhea infection in women lead to

A

pelvic inflammatory disease

38
Q

def? n. gonorrhoeae infection in the skin and joints with septicemia

A

gonococcemia

39
Q

who is more likely to get gonococcemia

A

women

40
Q

what is the main symptom of gonococcemia

A

septic arthritis

41
Q

what is the eye infection of n. gonorrhoeae called

A

purulent conjuctivitis

42
Q

what is the anal infection of n. gonorrhoeae called

A

anorectal gonorrhea

43
Q

what is the throat infection of n. gonorrhoeae called

A

pharyngitis

44
Q

where are the n. meningtidis epidemic

A

developing countries

45
Q

where is the meningitis belt

A

africa

46
Q

how is n. meningitidis spread

A

respiratory droplets by prolonged close contact

47
Q

what is the likely disease? child with fever and vomiting with neck stiffness

A

meningitis

48
Q

what is the likely disease? skin lesion is meningeal signs

A

meningococcemia

49
Q

if n. meningitidis gets into the respiratory tract what does it cause

A

pneumonia

50
Q

how is neisseria diagnosed in the lab (3)

A

gram stain, PCR, and culture

51
Q

if someone has a asymptotic neisseria infection is a gram stain a good way to diagnosis

A

no

52
Q

is there a vaccine for n. gonorhoeae

A

no

53
Q

is there a vaccine for n. meningitidis? if so who

A

yes 2 only for teens and elderly.