Necrobiotic Xanthogranuloma

Question 1

clinical presentation of Necrobiotic xanthogranuloma:

Answer 1

firm yellow xanthomatous plaques and nodules most commonly in periorbital region

- Plaques often ulcerate leading to scarring

Question 2

Necrobiotic xanthogranuloma is most strongly a/w______

Answer 2

IgG kappa monoclonal gammopathy

Question 3

Test to order if you diagnose Necrobiotic xanthogranuloma:

Answer 3

SPEP to look for monoclonal gammopathy (most commonly IgG kappa)

Question 4

Histopathology of Necrobiotic xanthogranuloma will reveal:

Answer 4

Question 5

Treatment for Necrobiotic xanthogranuloma:

Answer 5

none effective, treat underlying gammopathy