Neck masses Flashcards

1
Q

Name 3 true emergencies involving a neck mass

A

Respiratory distress
Vascular compromise
Cervical spine cord compression

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2
Q

What components of the PEx are important for evaluating a child with a neck mass?

A
ABCs
Level of consciousness
Work of breathing
Evaluate for stridor, hoarseness, dysphagia, and drooling
Neuro exam
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3
Q

DDx for neck masses

A
CONGENITAL
Hemangiomas
Cystic hygromas
Preauricular pits, sinuses, cysts
Thyroglossal duct cysts
Sternocleidomastoid mass
Cervical ribs
Brachial cleft abnormalities

INFECTIOUS
Lymphadenitis
Soft tissue abscess
Infected cysts (ie thyroglossal duct, brachial cleft, dermoid)

NEOPLASTIC 
Lymphomas
Thyroid neoplasms
Teratoma
Rhabdomyosarcoma
Neuroblastoma

TRAUMATIC
Subcutaneous emphysema
Hematoma
Cervical spine trauma

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4
Q

What are the anatomic classification of a neck mass and most common masses for each?

A
MIDLINE
Thyroglossal duct cyst
Lymphadenopathy
Dermoid cyst
Epidermoid cyst
Parotitis
Ectopic thyroid tissue
LATERAL
Lymphadenopathy
Cystic hygroma
Branchial cleft cyst
Sternocleidomastoid mass
Sialadenitis
Thyroid gland tumors
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5
Q

Define cystic hygroma

A

Malformation of the congenital failure of the lymphatic primordial buds to establish drainage into the venous system
Leads to the accumulation of lymphatic fluid and cyst formation
Discrete, soft, non-tender, mobile masses in the posterior triangle of the neck
80-90% appear by the end of the second year of life
10-20% at birth

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6
Q

What are the most common locations of cystic hygroma?

A

Near large veins and lymphatic ducts

Lateral neck (75%)
Axilla (20%)
Mediastinum (5%)
Retroperitoneum (5%)
Pelvis (5%)
Groin (5%)
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7
Q

What is the most serious complication of a cystic hygroma?

A

Respiratory compromise and compression of the airway

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8
Q

Define thymic cyst

A

Due to faulty implantation of thymic tissue in the neck during embryologic descent into the chest

Midline masses
But can be present anywhere along the angle of the mandible and the midline of the neck

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9
Q

What is the most common head and neck congenital lesion identified in infancy

A

Hemangiomas

Usually after the 1st month of life
F>M

Soft, mobile, non-tender
Bluish or fiery red hue
Regressing hematomas are grey
Most common locations - face (lips, nose eyelids, ears), scalp

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10
Q

List some of the complications of hemangiomas

A
Hemorrhage
Ulceration
Infection
Necrosis
Thrombocytopenia and coagulopathies (due to platelet trapping, Kasabach-Merritt syndrome)
Airway compromise
CHF
Visual impairment with some periorbital hemangiomas
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11
Q

Define branchial cleft cyst

A

Develop from malformations of the branchial arches (1st -4th)
Most commonly from the 2nd

Usually presents with a single painless cystic lesion deep to the anterior upper 1/3 sternocleidomastoid
Mobile, smooth, tense, and non-translucent and occasionally has clear mucoid drainage from a small opening

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12
Q

What are the most common complications of branchial cysts?

A

Infection

Tx with Abx, warm soaks
Definitive Tx - complete excision of the cyst and tract

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13
Q

Compare dermoid and epidermoid cysts

A

DERMOID CYSTS
Congenital
Inclusion of embryonic epidermis within embryonal fusion planes
Contents: lined by epithelium and contains sebaceous glands, hair follicles, connective tissues, and papillae
Location: Head and neck, lateral to supraorbital palpebral ridge, midline face, especially nasal bridge or neck
Can have intracranial extension (CT/MRI helpful to identify full extent of the lesion)
Tx: surgical excision

EPIDERMOID CYSTS
Traumatic or inflammatory
Follicular infundibulum of the hair shaft
Contents: Lined by epithelium, does not contain cutaneous appendages but rather keratinized debris
Location: Head and neck, lateral to the suprorbital palpebral ridge, midline face, especially nasal bridge
T: surgical excision

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14
Q

Describe a thyroglossal duct cyst

A

Common congenital neck mass
Due to a ductal ectodermal remnant that never obliterated
No external opening
Commonly found in kids 2-10 years
Midline cystic structure, immediately adjacent to the hyoid bone, at the level of the thyroid cartilage
3% sublingual
7% substernal
Soft, smooth, nontender
Moves when the child swallows or with tongue protrusion
CLINICAL DIAGNOSIS

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15
Q

What type of lymphadenopathy is concerning?

A

Supraclavicular - worry about malignancy (lymphoma)

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16
Q

What is the most common cause of acute cervical lymph node enlargement?

A

Infection

  • Viral - most common (EBV, adenovirus)
  • Bacterial (Staph, GAS, Strep pneumo, anaerobes, Barontella)
Presents with:
URI
Pharyngitis
Tonsillitis
Rapid enlargement of multiple adjacent nodes
Marked redness, swelling and warmth 
Sometimes spontaneous drainage 
Can process to a retropharyngeal abscess
Tx with PO Abx, unless toxic (IV Abx) 
If fluctuant - drain it
17
Q

DDx of subacute or chronic cervical lymphadenitis

large, minimally tender, mildly inflamed, nonfluctuant node with no associated prodromal illness

A
Reactive response to a nonspecific infection (bacterial/viral)
Cat scratch disease
Infectious mononucleosis
Mycobacterium tuberculosis (Typical or atypical)
Toxoplasmosis
CMV
HIV
Sarcoidosis
Histoplasmosis
Actinomycosis
Malignancy
18
Q

What is the workup for subacute or chronic cervical lymphadenitis

A

Complete Hx and PEx
Child’s overall general appearance
Assess the number, size and location of lymph nodes
Palpate for organomegaly
Labs - consider CBCD, EST, CXR, TB skin test
Abx to cover for Staph/Strep
Follow up/Disposition plan
Refer for biopsy if not responding to Abx therapy x 2 weeks and no other cause found

19
Q

Describe the clinical picture of cat scratch disease

A

Unilateral tender node
Exposure to cat/kittens
Papule (scratch site) and lymphadenopathy usually develop 1-2 weeks after
Self-resolves in 6-8 weeks

Tx - warm compresses and analgesics
Abx - for severe local disease or systemic Sx
(Azithro, Septra)

20
Q

How do you test for cat scratch disease

A

Bartonella henselae enzyme immunoassay (best initial test)

If negative –> B. henselae PCR from biopsy

21
Q

What are the symptoms of Kawasaki disease?

A

HOT CREAM

HOT - Fever > 5 days

C - Conjunctivitis
R - Rash
E - Erythema of the hands and feet
A - Adenopathy
M - MM involvement (strawberry tongue)

Other findings:

  • elevated ESR
  • elevated PLT
  • normocytic anemia
  • sterile pyuria
  • abnormal lipid profile
  • Echo - need to do to rule out coronary aneurysms
22
Q

What is the most common neoplasm of the neck based on age?

A
PRESCHOOL AGE
Neuroblastoma
Non-Hodgkin's lymphoma
Rhabdomyosarcoma
Hodgkin's lymphoma
SCHOOL AGE
Lymphoma
Hogdkin's/Non-hodgkin's lymphoma
Thyroid carcinoma
Rhabdomyosarcoma

ADOLESCENT
Hodgkin’s lymphoma

23
Q

What signs and symptoms of a neck mass make you more concerned about a neoplastic lesion?

A

Painless
Firm
Fixed

Unilateral ptosis
Nasal obstruction
Otorrhea