Neck Masses Flashcards

0
Q

how do you diagnose lateral neck masses that are suspected to be congenital?

A

CT scan: Will appear as a cystic mass medial to the sternocleidomastoid muscle at the level of the hyoid bone

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1
Q

Differential diagnosis for a neck mass.

A

“CCoNSuLLTSS”

C - Congenital - TBD, Thyroglossal duct cyst, Branchial cleft, Dermoid
C - Carotid Anerysm, Carotid body tumor
o
N - Neuroma, Neurofibroma
S - Soft Tissue - ‘PALS’ 1 tumor, Abscess, Lipoma, Sebaceous cyst
u
L - Lymph node - ‘MIRL’’ Mets, inflammatory, reactive, lymphoma
L - Lipoma
T - Thyroid: ‘CCG’ Cyst, Cancer, Goiter
S - Salivary - submandibular or preauricular
S - Supraclavicular - Lymphoma or metastatic tumor

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2
Q

What is the treatment for a congenital lateral neck mass?

A

(1) FNA to exclude cystic mets from squamous cell carcinoma or waldeyers tonsillar ring
(2) surgical excision is curative

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3
Q

Diagnosis for a central congenital neck mass?

A

Clinical – thyroglossal duct cyst

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4
Q

What is the treatment for a thyroglossal duct cyst?

A

Sistrunk procedure- excision with a segment of the hyoid bone

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5
Q

Treatment for inflammatory conditions?

A

Observation plus/minus abx

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6
Q

Infectious process in neck with HIV

A

FNA to rule out lymphoma

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7
Q

What tests should you order for the workup of a thyroid nodule?

A

(1) TSH if abnormal risk of malignancy < 5%
(2) ultrasound – cystic or solid?
(3) FNA – If cystic send fluid for cytology

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8
Q

Fine needle aspiration of thyroid nodule reveals cystic fluid. You send for cytology, what are the possible results and management?

A

Benign and cyst resolves -> f/u exam

Benign and solid component -> repeat FNA

Malignant-> treat as thyroid cancer, Partial or total thyroidectomy, lymph node dissection, radioactive iodine ablation

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9
Q

A fine needle aspiration is performed on a thyroid nodule. The mass is solid. What is the next step?

A

Send cells for cytology:

Benign -> Levothyroxin suppression, repeat FNA in six months

Suspicious 4 categories of types of cells: PAM F papillary, atypical (medullary), malignant, follicular

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10
Q

Fine needle aspiration is performed on a thyroid nodule. Cells are sent to pathology after a solid mass is found. Name the types of cells that would be suspicious, and the next steps and management?

A

Papillary – thyroid scan – if cold thyroid lobectomy
– If functioning, less than 1% risk for malignancy
Atypical – medullary cancer – calcitonin test
Malignant – treat as thyroid cancer
Follicular or hurthle cells – Thyroid lobectomy

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11
Q

If salivary nodule is suspected how do you diagnose?

A

CT scan of the neck

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12
Q

Treatment for salivary nodule?

A

FNA

Excise if malignant

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13
Q

Management of a cervical lymph node?

A

If suspicious primary site is present: pan endoscopy with biopsy of primary site and screening for secondary sites

Treatment – resection of primary site, en block removal of lymph nodes, radiation, chemotherapy

If no suspicious site: fine needle aspiration

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14
Q

Management of supraclavicular lymph node

A

Chest x-ray, bronchoscopy, Mammogram, upper G.I. series, CT of the abdomen looking for primary. If no primary, fine needle aspiration or excisional biopsy

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15
Q

How do you diagnose a carotid body mass?

A

History of nonpainful pulsatile mass at carotid bifurcation. Lyre sign on carotid angiogram
Biopsy contraindicated due to vasculature

16
Q

Treatment for carotid body mass?

A

Excision

Preoperative embolization for masses greater than 3 cm

17
Q

Diagnosis of carotid body aneurysm?

A

Doppler ultrasound, angiogram or MRA

18
Q

What findings on CT of the neck with contrast would suggest a malignancy?

A

– Hypodense lucency to core
– Greater than 1.5 cm
– loss of edge sharpness

19
Q

Tx for medullary cancer?

A

Total thyroidectomy + LN dissection

20
Q

First diagnostic test for neck mass

A

CT with contrast of head and neck

21
Q

Enlarged lymph node is found in neck. Next step?

A

Excisional biopsy. Tx is based on primary tumor

22
Q

Gene for MEN1?

A

Menin gene, tumor suppressor gene, AD

23
Q

MEN1 syndrome

A

Hyperparathyrodiism >90%,
pancreatic neuroendocrine tumors PNETS 70%, gastrinoma
Pituitary tumors 30%

24
Gene involved in MEN2A
RET, oncogene, AD
25
MEN2A
Medullary thyroid cancer - 100% Pheochromocytoma - 50% Hyperparathyroidism - 50%
26
Patient with hypercalcemia. First step?
Order PTH - fi high, primary hyperparathyroidism 99.9% of the time Check urine calcium - normal or high in primary HPTHism.
27
MEN2B
Thyroid medullary carcinoma Pheochromocytoma Mucosal neuromas - body habitus
28
When should the parathyroid gland be removed?
Any symptomatic disease (stones, bones, psychic moans, GI groans) Renal insufficiency, no matter how slight Very elevated serum calcium >12.5 T score < -2.5 or fragility fracture
29
Cushings disease
Any form of hyperadrenalism or hypercortisolism, no matter what the cause
30
How do you diagnose the presence of Cushing's syndrome
1 mg overnight dexamethasone suppression test | 24-hour urine cortisol - adds specificity
31
How do you diagnose the location or origin of Cushing's syndrome?
ACTH Level ACTH level high: Pituitary or ectopic source - scan chest for lung cancer or carcinoid. ACTH low: Adrenal source