NCLEX Flashcards
Hemoglobin
Female 123-157
Male 140-174
Responsible for transporting O2
Hematocrit
Female 37-47%
Male 42-52%
Concentration of RBC in the body
RBC
4.5-5.5 million
WBC
5000-10000
Platelets
150000-400000
Help clot and stop bleeding
Partial thrombin time (PTT)
20-30 seconds
PTT on heparin
rate should be 1.5-2.5x patients normal
Prothrombin time (PT)
10-12 seconds
International normalized ratio (INR)
0.9-1.2
INR on warfarin
therapeutic INR 2-3
sodium normal
135-145
potassium normal
3.5-5.0
calcium normal
9-10.5
magnesium normal
1.5-2.5
chloride normal
98-106
phosphorous normal
2.5-4.5
BUN
10-20
*increases when kidneys do not filter urea waste
creatinine
0.6-1.2
troponin
0-0.4
BNP
<100
*when fluid retention is present, the heart senses the need to pump harder and release BNP
total cholesterol
<200
HDL normal
> 55
*responsible for cleaning out arteries and reduces plaque / build up
LDL normal
<130
*clogs arteries
Triglycerides (very LDL)
<160
urine specific gravity
- 1.005-1.030
- increased ; dehydration
- decreased ; diluted urine
urine osmolarity
- 300-900
- number of particles in urine
- increased ; dehydration
- decreased ; diluted urine
urine WBC
0-4
*increased; inflammation, UTI
protein in urine
should be negative
*if positive; kidney disease, preeclampsia
ABG normals
pH normal ; (acidosis) 7.35 – 7.45 (alkalosis)
HC03 normal ; (acidosis) 22-28 (alkalosis)
CO2 normal ; (alkalosis) 35-45 (acidosis)
*fully compensated if pH is normal
causes of hypernatremia (HINT: models)
- medications
- osmotic diuretics
- diabetes
- excessive water loss
- low water intake
- sodium intake too high
signs and symptoms of hypernatremia (HINT: fried and salted)
- fever
- restlessness and agitation
- increased fluid retention
- edema
- dry mouth
- skin flushed
- altered LOC
- low urinary output
- thirst
- elevated BP
- decreased energy
causes of hyponatremia (HINT: mobs fail)
- meds – diuretics
- oral gastric tube suctioning
- burns
- SIADH
- Failure of kidney, heart, liver
signs and symptoms of hyponatremia (HINT: low sodium)
- LOC altered
- orthostatic hypoTNS
- weak muscles
- seizures
- osmolarity low (serum)
- diarrhea
- increased ICP
- urine osmolarity high
- more bowel sounds
causes of hyperchloremia
- dehydration
- vomiting
- sweating
- excess steroids cause chloride retention
causes of hypochloremia
- CHF
- water intoxication
- salt losses (burns, sweating, v&d)
cause of hyperkalemia
- medication
- acidosis
- cellular destruction
- hypoaldosteronism
- intake
- nephrons – renal failure
- excretion impaired
causes of hypokalemia
- drugs
- inadequate K+ intake
- too much water
- Cushing’s disease
- heavy fluid loss
causes of hypercalcemia
- malignancy
- diuretics
- steroids
- parathyroid
- immobilization
- endocrine
- D vitamin
causes of hypocalcemia
- celiac, chrons disease (malabsorption)
- hypoparathyroidism
- alcoholism
- malnutrition
- pancreatitis
- renal failure
causes of hyperphosphatemia
- hypocalcemia
- tumor lysis
- renal faliure
causes of hypophosphatemia
- malnutrition
- alcoholism
- TPN
- hypercalcemia
foods high in vitamin C
- citrus fruits
- strawberries
foods high in vitamin D
- fortified milk and cereal
foods high in vitamin K
- leafy greens
foods high in vitamin B12
- protein
- dairy
- eggs
foods high in folic acid
- dark green veggies
- legumes
- nuts
foods high in iron
- meats
- eggs
- leafy greens
foods high in potassium
- avocados
- oranges
- yogurt
- milk
- salmon
- bananas
foods high in calcium
- cheese
- leafy greens
- milk
- salmon
- almonds
- tofu
- yogurt
foods high in phosphorus
- dairy
- chocolate
- cola
- nuts
- beans
- meats
- grains and seeds
foods high in sodium
- soy sauce
- condiments
- canned food
- processed meat
- popcorn
renal diet
- fluid restriction
- low electrolytes
- low protein
- high calcium
grapefruit juice and medication contraindication
*inhibits enzyme in liver needed to metabolize these meds
- nifedipine
- verapamil
- statins
- midazolam
- SSRIs
acetaminophen antidote
acetylcysteine
benzodiazepine antidote
flumazenil
heparin and enoxaparin antidote
protamine sulfate
warfarin antidote
phytonadione (vitamin K)
local anesthetics
*END IN -CAINE
- indicated for painful procedures and localized pain and discomfort
opioid agonists
*END IN -INE OR -ONE
*example; morphine, oxycodone, fentanyl
*MONITOR FOR RESP. DEPRESSION
- indicated for moderate to severe pain relief
opioid antagonist
*END IN -ONE
*exmaples; naloxone, methynaltrexone
- indicated for opioid overdose
NSAIDs
*examples; naproxen, ibuprofen, ASA, ketorolac
- indicated for inflammation, pain, fever
acetaminophen
- no anti-inflammatory properties
- indicated for pain and fever
- taking with alc. can cause major liver damage
- max dose is 4000 mg daily
COX-inhibitors
*RISK FOR
- renal impairment
- vasoconstriction
- bleeding
- gastric ulcers
ACE inhibitors
*END IN -PRIL
- indicated for HTN, CHF
- blocks conversion of angiotensin I to II
ARBs
*END IN -SARTAN
- indicated for HTN, DM neuropathy, CHF
- inhibits angiotensin II
Calcium channel blockers for heart and bv
*END IN -MIL
- indicated for HTN, angina, afib/flutter
- block calcium channels in BV (vasodilation) and heart (slow HR and decrease contraction force)
calcium channel blockers bv only
*END IN -DIPINE
*WILL NOT CAUSE CONSTIPATION
*INTERACTS WITH GRAPEFRUIT
- indicated for HTN, angina
- block calcium channels in BV (vasodilation)
sodium channel blockers
*PROCAINAMIDE, LIDOCAINE
- indicated for dysrhythmias
- slow impulse conduction and delays repolarization
beta blockers
*END IN -LOL
- indicated for HTN, angina, arrhythmias, MI, anxiety, alc. Withdrawal
- block beta 1 and 2 adrenergic receptors to slow HR
potassium channel blockers
*AMIODARONE, IBUTILIDE
- indicated for dysrhythmias
- block potassium currents to prevent repolarization, interfering with excitatory pathways
atropine
- indicated for excessive secretions, sinus bradycardia, heart block
digoxin
- cardiac glycoside
- indicated for HF, afib, a flutter, CHF, cardiogenic chock
- increases heart contractility and decreases the rate
adenosine
*GIVE IV PUSH CLOSE TO HEART AND QUICK
*WARN PT IT WILL FEEL LIKE A KICK TO THE CHEST
- indication for SVT
- interrupts re-entry pathways through AV node, restoring sinus rhythm
H1 antagonists
*END IN -INE
- indicated for allergy, anaphylaxis, sedation
- blocks H1 receptors, decreases flushing, edema, secretions, itching, pain
glucocorticoids
*END IN -IDE, -ONE
*INHALE CAN CAUSE THRUSH
*DO NOT USE ORAL FOR MORE THAN 10 DAYS
- indicated for asthma, COPD, allergies
- decreases inflammatory mediators, infiltration of inflammatory cells, and vascular permeability
Leukotriene receptor antagonists
*END IN -KAST
- indicated for asthma, COPD, allergies
- suppress leukotrienes to decrease smooth muscle constriction / edema
monoclonal antibodies
*END IN -ZUMAB
*ANAPHYLAXIS MAY OCCUR IF AMNIN SQ
- indicated for asthma, COPD, allergies
- reduce amount of IgE in blood to limit trigger of an inflammatory reaction
B2-adrenergic agonists
*END IN -OL
*USE SHORT ACTING THEN LONG IN 1 MIN INTERVALS
- bind to beta2 receptors in airway leading to relaxation of smooth muscles
Methylxanthines
*END IN -LINE
*NARROW THERAPEUTIC WINDOW
- relaxes bronchial smooth muscle
Anticholinergics
*END IN -IUM, -BROMIDE
- block muscarinic receptors in bronchi causing less bronchoconstriction
Guaifenesin
- indicated for excess mucus
- stimulates flow of respiratory tract secretions making a more productive cough
Mucolytics
*HYPERTONIC SALINE, ACETYLCYSTEINE
- indicated for excess mucus
- reacts with mucus to make it more watery
decongestants
*PHENYLEPHRINE, PSEUDOEPHEDRINE
- activates alpha 1 adrenergic receptors on nasal blood vessels causing vasoconstriction
alpha adrenergic agonists
*EPINEPHRINE, NOREPINEPHRINE, EPHEDRINE, PHENYLEPHRINE
- indicated for cardiac arrest, shock, control bleeding anaphylaxis
- activates alpha receptors resulting in vasoconstriction and pupil constriction
beta adrenergic agonists
*EPINEPHRINE, NOREPINEPHRINE, DOPAMINE, DOBUTAMINE, ISOPROTERENOL
- indicated for AV block, cardiac arrest, shock, HF, preterm labor
- activates beta receptors causing SNS stimulation resulting in increased HR (B1), bronchodilation (B2), uterine relaxation (B2)
*SIDE EFFECTS; tachycardia, HTN, CNS overstimulation
alpha adrenergic antagonists
*END IN -ZOSIN
- block activation of alpha receptors in SNS causing vasodilation, decreased BP
beta adrenergic antagonists
*END IN OLOL
- block activation of B1/B2 in SNS
cholinergic medications
*END IN -STIGMINE
- cause REST AND DIGEST; increase GI secretions and motility, increase urination, pupil constriction, decrease HR
anticholinergic medications
- block acetylcholine in PNS thereby blocking REST AND DIGEST
anti-parkinson’s medication
*LEVODOPA
- increases dopamine synthesis and can decrease motor symptoms
cholinesterase inhibitors
*DONEPEZIL, RIVASTIGMINE, GALANTAMINE
- indicated for Alzheimer’s, dementia
- prevents acetylcholine breakdown which resulting in improved memory
long term anticonvulsants
*PHENYTONIN, PHENOBARBITAL, VALPROIC ACID
- selectively inhibit sodium channels, suppressing action potentials in hyperactive neuros
rapid acting anticonvulsants
*LORAZEPAM, DIAZEPAM
- causes CNS depression
H2 antagonists
*END IN -IDINE
- block release of histamine which blocks acid secretions
Proton pump inhibitor
*END IN -ZOLE
- prevent the transport of H ions into gastric lumen to decrease gastric acid production
GI protecetant
*SUCRALFATE
- promotes healing of ulcers by providing barrier over them
Loop diuretics
*END IN -IDE
- indicated for low urinary output, edema, CHF, BP management
thiazide diuretics
*END IN -THIAZIDE
- indicated for HTN, edema
potassium sparing diuretics
*END IN -ONE
- indicated for HTN, edema, HF
steroids
*END IN -SONE
- indicated for Addison’s disease, inflammation, allergy, autoimmune disorders
- suppresses inflammation in immune system
thyroid hormone replacements
*LEVOTHYROXINE
- take every day, same time, empty stomach, separate from other medications
anti-thyroid medications
*IODINE, RADIOACTIVE IODINE, METHIMAZOLE
- reduces size and vascularity of thyroid gland or kills thyroid cells
ADH (antidiuretic hromone)
*VASOPRESSIN, DESMOPRESSIN
- indicated for DI, shock
- causes body to retain water, increasing blood volume, decreasing UOP and increasing BP
thrombolytics
*END IN -ASE
- enzyme that converts plasminogen to plasmin, plasmin destroys a clot
penicillins
*END IN -CILLIN
- antibiotic
cephalosporin
*STARTS WITH CEP-
- antibiotic
carapenems
*END IN -PENEM
- antibiotic
tetracyclines
*END IN -CYCLINES
- antibiotic
macrolides
*END IN -MYCIN
- antibiotic
aminoglycosides
*END IN -CIN
- antibiotic
sulfonamide
*START WITH SULF-
- antibiotic
anti-tuberculosis agents
*ISONIAZID - kills mycobacteria that are actively dividing
*RIFAMPIN - bactericidal
amphotericin
- for systemic fungal infections
azoles
*END IN -AZOLE
- for systemic or topical fungal infections
fungins
*END IN -FUNGIN
- antifungal medications
Benzodiazepines
*END IN -LAM, -PAM
- indicated for anxiety
- avoid alc., monitor for resp. depression
SSRIs
*END IN -INE
- antidepressant
- prevent reuptake of serotonin increasing availability
*MONITOR FOR SEROTONIN SYNDROME - HTN, confusion, anxiety, tremors, ataxia, sweating
*MONITOR FOR SUICIDE FOR 2-3 WEEKS
TCAs
*END IN -PTYLINE
- antidepressant
- prevent reuptake of serotonin / norepinephrine
*SIDE EFFECTS; tachycardia, cardiac effects, anticholinergic effects, sedation
MAOIs
*ISOCARBOXAZID, PHENELZINE
- antidepressant
- block enzymes to increase ALL neurotransmitters
*NO FOOD WITH TYRAMINE (aged cheese, wine, pickled meat). will cause HTN crisis
Lithium
- mood stabilizer indicated for mania
- inhibits excitatory neurotransmitters and promotes GABA
*DO NOT admin with NSAIDs
*THERAPEUTIC RANGE; 0.6-1.2
first generation antipsychotics
*HALOPERIDOL
- indicated for schizophrenia, mania, aggression, agitation
- inhibits dopamine
*MONITOR FOR tardive dyskinesia, slurred speech, tremors, neuroleptic malignant syndrome (high fever) prolonged QT wave
second generation antipsychotics
*END IN -APINE
tocolytics
*TERBUTALINE, MAGNEIUM SULFATE
- binds to beta 2 adrenergic receptors to slow contractions
*SIDE EFFECTS; CNS overstimulation (terb.), hypermagnesemia (mag.)
oxytotics
*OXYTOCIN
- stimulate contractions in labor or PPH
prostaglandin E1
*MISOPROSTOL
- ripen cervix
prostaglandin E2
*DINOPROSTONE
- ripen cervix
nitrous oxide
- gas mixed with O2
- reduces anxiety, causes feeling of well-being
narcotics used in labor
- meperidine
- butorphanol
- morphine
- nalbuphine
*CAN CROSS PLACENTA so monitor for resp. depression
epidural
- regional anethesia
- small catheter placed into lower spine and pain medication is given
spinal block
- indicated for pain control during C-section
- injected directly into fluid of the spinal cord and will block pain for a few hours
drugs to avoid in children
- ASA (reye’s syndrome)
- Ibuprofen before 6 mo. (immature liver)
- tetracycline (tooth discolouration)
- oseltamivir (hallucinations)
inotropes
- go directly to the heart to increase myocardial contractility force
vasopressors
- mimic SNS to cause vasoconstriction
- indicated for MI, hypoTNS, shock
medication for septic shock
1st; dopa or norepi
2nd; epi or phenylephrine
3rd; vasopressin
milrione
- indicated for cardiogenic chock, decreased CO, heart defects
- causes systemic vasodilation decreasing after load and increasing contractility
- inhibits phosphodiesterase
cardiac output formula
CO = stroke volume X heart rate
PICC
needed when several weeks of infusions are needed (chemo, antibiotics, TPN)
ECG normal findings
- 1 P wave for every QRS
- PR interval between 0.12-0.20
- QRS less than 0.12 seconds
- Rate between 60 and 100
- Regular rhythm
*LITTLE BOXES 0.04
first degree heart block ECG
PR interval >0.20
second degree heart block (type 1) ECG
PR normal, then longer, then longer, then drops
second degree heart block (type 2) ECG
No P wave for every QRS
third degree heart block ECG
variable PR wave
tall peaked T waves indicate …
hyperkalemia
shallow / inverted T waves & U wave indicate ….
hypokalemia
tall, unpeaked T waves indicate …
Hypermagnesemia
beneficence
doing good
nonmaleficence
do no harm
accountability
accepting responsibility for your actions and accepting consequences
fidelity
keep your promises and be faithful
autonomy
encourage patient to make their own decisions without judgement or coercion
veracity
tell the truth and not withholding any part of the truth
orthodox jewish
*KOSHER DIET
- no shellfish
- no pork
- do not combine meats / dairy in same meal
*PT NEEDS WRAPPED PLASTIC UTENSILS / PREP THEIR OWN MEAL
Halal diet
- no alc.
- no pork
- meat must be slaughtered religiously
seventh-day adventisit church
- no alcohol
- no caffeine
- lacto-ovo vegetarians
- no meat / pork
hinduism diet
- no eggs
- dairy ok
- no meat - esp. beef
where are steroids produced
produced by adrenal cortex
glucocorticoids effects
- mood
- immunosuppression
- break down fat and proteins
- inhibit insulin
mineralcorticoids effects
- retain sodium and water
- excrete potassium
(example; aldosterone)
where are catecholamines from
secreted by adrenal medulla
antidiuretic hormone
- secreted from pituitary gland
- retains water but not sodium
- medication replacement ends in -PRESSIN
thyroid hormone
- provide energy for metabolism
- TSH controls release of T3/T4
- low T3/T4 cause high TSH
- levothyroxine is T4 med. replacement
thyroid hormone negative feedback loop
- blood has low T3/T4 levels
- hypothalamus increases TRH
- pituitary increased TSH
- thyroid increases T3/T4
parathyroid hormone (PTH)
controls calcium levels by pulling from bones into blood
calcitonin
- released when serum calcium levels increase
- inhibit osteoclasts
metformin nursing considerations
- do not give in renal and hepatic impairment
- monitor BUN, Cr
- take with food
- hold 24hrs before and 48hrs after IV contrast studies
addison’s disease
- TOO little steroids
- low cortisol; fatigue, wt loss, hypoglycemia
- low aldosterone; low sodium and water, potassium retention, hypoTNS
cushing’s disease
- TOO much steroids
- high cortisol; immunosuppression, mood alteration, fat redistribution
- high aldosterone; fluid and sodium retention, potassium excretion
*remember moon face, buffalo hump, weight in abdomen
conn’s disease
too much aldosterone
pheochromocytoma
- too much catcholamines due to tumour on adrenal gland
- s&s; tachycardia, palpitations, HTN, diaphoresis
*DO NOT PALPATE ABDOMEN IF SUSPECTED DT RISK OF RUPTURING TUMOUR
diabetes insipidus
- not enough ADH in the body
- s&s; drying effects, tachycardia, hypoTNS
- decreased USG
- increased Na, HCT, serum osmolarity
what to monitor after parathyroidectomy
- monitor for hypocalcemia
crackles
- sounds like wood burning in a fire place, popping
- air moving through mucous, fluid
rhonchi
- low-pitched, snoring
- secretions in airway
wheezes
- high pitched musical sound
- airway constriction
diminished
- quiet
- shallow or restricted breathing
stridor
- high pitched inspiratory sound
- upper airway obstruction
HIGH ventilator alarms
*HIGH PRESSURE
caused by;
- coughing
- gagging
- bronchospasm
- fighting ventilator
- ETT occlusion
- kink in tubing
- increased secretions
- thick secretions
- water in ventilator circuit
LOW ventilator alarms
*LOW PRESSURE
caused by;
- disconnected tubing
- loose connections
- leak
- extubation
- cuffed ETT or trach is deflated
- poorly fitted mask
why would a client need a chest tube?
- pneumothorax
- euffusions
- abscess
- cancer
- hemothorax
drainage collection chamber (chest tube)
- connected to patient
- air, fluid, blood drains into here
- no tidaling / bubbling
water seal chamber (chest tube)
- tidaling (up when pt breaths in)
- intermittent bubbling
- ensures suction is a closed system
suction control chamber (chest tube)
- connected to suction
- no tidaling
- gentle bubbling
- replace with sterile water PRN
montelukast
- leukotriene modifier
- managed allergic rhinitis, allergies, asthma
- long term to prevent attacks
- regulate mass cells
guaifenesin
- expectorant to loosen mucus and stimulate cough
assessment findings for COPD
- barrel chest dt hyper-inflated lungs
- accessory muscle use
- congestion
- diminished, crackles, wheezes
- acidotic
- hypercarbic
- hypoxic
pneumonia diagnosis
- CXR; patchy infiltrates
- sputum culture identifies bacterial source
air embolism positioning
left lateral trendelenburg (durant’s maneuver)
pulmonary embolism positioning
high fowlers
cranial nerve I
olfactory - smell
cranial nerve II
optic - vision
cranial nerve III
oculomotor - pupil contriction
cranial nerve IV
trochlear - downward eye movement
cranial nerve V
trigeminal - jaw movement, sensation of face and neck
cranial nerve VI
abducens - lateral eye movement
cranial nerve VII
facial - facial movement, taste of 2/3 of tongue
cranial nerve VIII
vestibulocochlear - hearing and balance
cranial nerve IX
glossopharyngeal - swallowing, taste on posterior 1/3
cranial nerve X
vagus - swallowing, speaking
cranial nerve XI
spinal/accessory - flextion and rotation of head
cranial nerve XII
hypoglossal - tongue movements
normal ICP
5-15
ICP symptoms
- vomiting
- headache
- mental status changes; LOC, confusion
- eyes; pupillary changes, nystagmus
- speech; slurring, pressured
- cushing’s triad; increased systolic BP, decreased HR, altered respirations
decorticate posturing
- abnormal flextion
- arms pulled toward center
- clenched fists
- damage to midbrain
aphagia
inability to swallow
dysphagia
difficulty swallowing
aspirin and children
- can cause Reye’s syndrome if pt has viral infection
- commonly used in Kawasaki disease
decerebrate posturing
- abnormal extension
- arms and legs straight out
- toes pointed downwards with arched back
- damage to deep brain structures;pons
dysphasia / aphasia
impairment in comprehension or production of language
- receptive; damange to wernicke’s
- expressive; damage to broca’s
basilar skull fracture
- battle’s sign; bruising over mastoid process
- raccoon eyes; periorbital bruising
- cerebralspinal rhinorrhea; halo test positive and positive for glucose on glucometer
*NEVER PUT ANYTHING IN NOSE AS IT CAN GO INTO BRAIN
epidural hematoma
- dura peeled off skull
- rapid expansion or blood between dura mater and skull
subdural hematoma
- dura attached to skull
- slow expansion of venous blood between arachnoid matter and dura matter
hypertensive crisis treatment
- sit client up to lower BP
- administer antihypertensives
- tx underlying cause (ex. full bladder - cath, constipated - disimpact, pressure injury - reposition)
hemorrhagic stroke
- vessel ruptures and bleeds into brain
- increases ICP
- “worst headache of my life”
- tx; control bleeding, craniotomy
ishemic stroke
- clot blocks blood flow to brain
- thrombotic; in brain artery
- embolic; clogs blood vessel leading to brain
- tx; permissive HTN (ensures brain perfusion), antithrombotics (tPA), surgical removal
stroke symptoms
- balance; dizziness, headache
- eyes; blurry vision, unequal
- face; unilateral drooping
- arms; arm/leg weakness
- speech; difficulty
menengitis assessment findings
- nuchal (Neck) rigidity
- photophobia
- fever
- kernig’s sign; pt supine, bend leg up, INTENSE PAIN
- brudzinski’s sign; pt supine, passive neck flexion causes involuntary flexion of knees and hips
multiple sclerosis
- autoimmune disorder
- CNS inflammation
- damages mylein sheath
guillain-barré
- antibody immunologic response precipitated by viral or bacterial illness
- causes ascending weakness and paralysis
- 2 week peak, slow recovery
- tx underlying illness
neuropathy
weakness, numbness and pain from nerve damage
botulism
- toxin released by bacteria found in soil, dust, honey
- after 1 year you can digest better
- inhibits acetylcholine release
- descending paralysis
- tx antitoxin
myasthenia gravis
- autoimmune disorder where communication between nerves and muscle are destroyed
- diagnosed via TENSILON TEST
parkinsons
- progressive
- caused by degeneration of dopamine neurons
- symptoms; tremor, rigidity, akinesia / ataxia, postural instability
T cells
coordinate attack and/or directly kill pathogens