Navle Review

Question 1

Microcytic hypochromic

Cause

Answer 1

Iron deficiency

Question 2

Ddxn for small large animals with irons def anemia

Answer 2

SA: parasites (hookworms, ectoparasites with juveniles) GI ulcer, bleeding tumors
LA: parasites( barber pole and hemonchus contortis)

Question 3

Why Fe def (microcytic /normochromic) w/ PSS

Answer 3

Transferor (Fe transport protein) made in liver … required to transport Fe to BM

Question 4

How long for RBC regenerate - ie call “non regenerative”

Answer 4

3-5d

Question 5

HYPERCROMIC causes

Answer 5

Always artifact =
lipemia or
Heinz bodies

Question 6

Macrocytic Normochromic (big RBC) causes

Answer 6

Regeneration
FeLV (abnormal maturation)
“Poodle macrocytosis”

Question 7

Microcytic normochromic causes

Answer 7

Iron def/restriction
PSS
Akita microcytosis

Question 8

Extra vascular hemolysis RBC change and plasma

Answer 8

Spherocytes

Ictreric plasma

Question 9

CBC/ slide Changes that can be seen with IMHA

Answer 9

Spherocytes**
Autoagglutination
Inflamm leukogram (don’t be afraid to immunosuppress b/c think infxn)
Thrombocytopenia (thromboembolic/DIC?)

Question 10

Intravascular hemolysis RBC change and plasma

Answer 10

Ghost RBC hemolysis plasma and urine

Question 11

Who can you call spherocytes on? For IMHA

Answer 11

Dogs +/- bovine

Don’t call in cats or horses -aliens

Question 12

Extra vascular hemolysis order of bilirubin accumulation

Answer 12

Urine —> plasma —> tissue (>2)

Question 13

Intravascular hemolysis order of pigment buildup

Answer 13

Plasma (Hg binds a protein untill overwhelmed) —> urine

Question 14

Mycoplasma haemo…

Where in RBC
How to DXN
TX

Answer 14

Felis (cats) suis (pigs) canis (dogs)

Epicellular
PCR (cyclic in blood)
Tx doxycycline or Pradafloxacin

Question 15

Anaplasma marginale
What species
What look like

Answer 15

Bovine

Ddxn Howell-jolly body but on periphery and larger. (Basopholic inclusion)

Question 16

Babesia canis

What breeds common and tx

Answer 16

Large form Spider-Man
1/4 - 1/3 size of RBC
> greyhounds
Tx immiticarb

Question 17

Babesia gibsoni

Answer 17

Small form (signet ring) kinda like Howell-JB
>pit bulls 

AA Combo
Azithromycin atoviquone

Question 18

Horse babesia

Answer 18

Piroplasmosis 
Babesia caballi (large)
Theileria equi (small)

Reportable !!!

Question 19

Cat babesia (cytox)
(A cat babesia does exist but always call cytox)

Tx

Answer 19

Cytauxzoon felis
Small signet ring (ddxn HowellJB)
NON REGEN Anemia common

Tx doxycycline 
    Or flouroquinolones ( cyprofloxacin)

Question 20

When do you see Heinz bodies ( nose like end of cell)

Answer 20

Oxidative damage

Onion garlic/ acetametohin/ red maple/ propofol : zinc (pennies)

Question 21

3 things seen a/ oxidative damage

Answer 21

Heinz bodies
Eccentracytes
Methemoglobinemia

Question 22

Tick born causes of thrombocytopenia

Answer 22

Erlichiosis
Anaplasmosis
Ricketsiosis

Question 23

Hemophilia letters w/ factors

Answer 23

8= A
9= B
11= C

Question 24

Vit K dep factors

shortest 1/2 life

Answer 24

2 7 9 10

7 shortest 1/2 life

Question 25

What will prolong 1st with rodenticide tox

Answer 25

PT

Question 26

Large animal leakage enzymes

Answer 26

SDH and GLDH (also used exotic)

Question 27

AST sources

Answer 27

RBC muscle (check CK and PCV)

Question 28

Horses causes of liver dz

Answer 28

PA (pyrollizisidine alkaloid tocicosis)

Theilers dz = “serum sickness”

Foals w/ clostridium pillifomis = tyzzers dz

Question 29

Stain to see Heinz bodies

Answer 29

New methelene blue

Question 30

Horse babesias (reportable)

Answer 30

B. Caballi

Theleria equi