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Nausea & vomiting Flashcards

1
Q

What Phenothiazines are used for emesis

A

Compro-prochlorperazinePhenergan,Promethagan, Phenadoz-promethazineThorazine-chlorpromazine

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2
Q

What is the generic for Compro & Compazine

A

prochlorperazine

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3
Q

What is the generic for Phenergan, Promethagan, Phenadoz

A

promethazine

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4
Q

What is the generic for Thorazine

A

chlorpromazine

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5
Q

What is the mechanism of action of Phenthiazines

A

Block DA in the CNS & CTZ

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6
Q

Phenothiazines are contraindicated in which group?

A

children <2

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7
Q

What are the major side effects of Phenothizaines

A

CNS: EPS, drowsiness, seizuresanticholinergic effectsskin reactionsrespiratory depression

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8
Q

What is the max daily dose of Prochloperazine

A

40mg/day Compazine25mg/bid Compro (suppository)

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9
Q

What is the minimum age and weight that Compazine or Compro can be used for

A

2 years & 10kg

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10
Q

What is the max pediatric dose of Phenergan?

A

25mg/dose

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11
Q

What other conditions can Phenergan be used for

A

motion sickness, sedation

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12
Q

Can Phenergan be used for asthma symptoms?

A

No, contraindicated in all lower respirtory conditions

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13
Q

If a patient has sensetivities to 1 Phenotiazine, can another agent in the same class be used?

A

No, there is cross reactivity within the class

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14
Q

What is the brand name for scopolamine?

A

Transderm Scop

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15
Q

How is Transderm Scop used/applyed

A

1 patch behind ear ?4 hrs before exposure q3d prn (best if 12hrs before)

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16
Q

What is the antidote for EPS due to Phenothiazines?

A

Benadryl or Benztropine

17
Q

use of Phenergan via which rout is contraindicated?

A

SQ & intra-areterial

18
Q

Phenergan can cause damage to what system no matter the route of administration?

A

Tissue damage including gangrene

19
Q

What is the brand name for ondansetron

20
Q

What is the brand name for Granisetron tablets

21
Q

What is the brand name for Granisetron patch

22
Q

What is the brand name for dolasetron

23
Q

What is the brand name for palonosetron

24
Q

5HT3 antagonist have what significant warning

A

QT prolongation

25
Q

Side effects for 5HT3 antagonists

A

HA, drowsiness/dizziness, constipation/diarrhea

26
Q

Which 5HT3 antagonist is best for CINV 7 why

A

Sancuso patch (granisetron) because it last for 7 days

27
Q

What is the half life of Aloxil (palonestron)

28
Q

What OTC item can be used for mornig sickness

Nausea & Vomiting (1 decks)

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