Nausea & vomiting Flashcards

1
Q

What Phenothiazines are used for emesis

A

Compro-prochlorperazinePhenergan,Promethagan, Phenadoz-promethazineThorazine-chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the generic for Compro & Compazine

A

prochlorperazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the generic for Phenergan, Promethagan, Phenadoz

A

promethazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the generic for Thorazine

A

chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the mechanism of action of Phenthiazines

A

Block DA in the CNS & CTZ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Phenothiazines are contraindicated in which group?

A

children <2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the major side effects of Phenothizaines

A

CNS: EPS, drowsiness, seizuresanticholinergic effectsskin reactionsrespiratory depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the max daily dose of Prochloperazine

A

40mg/day Compazine25mg/bid Compro (suppository)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the minimum age and weight that Compazine or Compro can be used for

A

2 years & 10kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the max pediatric dose of Phenergan?

A

25mg/dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What other conditions can Phenergan be used for

A

motion sickness, sedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Can Phenergan be used for asthma symptoms?

A

No, contraindicated in all lower respirtory conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If a patient has sensetivities to 1 Phenotiazine, can another agent in the same class be used?

A

No, there is cross reactivity within the class

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the brand name for scopolamine?

A

Transderm Scop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is Transderm Scop used/applyed

A

1 patch behind ear ?4 hrs before exposure q3d prn (best if 12hrs before)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the antidote for EPS due to Phenothiazines?

A

Benadryl or Benztropine

17
Q

use of Phenergan via which rout is contraindicated?

A

SQ & intra-areterial

18
Q

Phenergan can cause damage to what system no matter the route of administration?

A

Tissue damage including gangrene

19
Q

What is the brand name for ondansetron

A

Zofran

20
Q

What is the brand name for Granisetron tablets

A

Kytril

21
Q

What is the brand name for Granisetron patch

A

Sancuso

22
Q

What is the brand name for dolasetron

A

Anzemet

23
Q

What is the brand name for palonosetron

A

Aloxi

24
Q

5HT3 antagonist have what significant warning

A

QT prolongation

25
Q

Side effects for 5HT3 antagonists

A

HA, drowsiness/dizziness, constipation/diarrhea

26
Q

Which 5HT3 antagonist is best for CINV 7 why

A

Sancuso patch (granisetron) because it last for 7 days

27
Q

What is the half life of Aloxil (palonestron)

A

40 hours

28
Q

What OTC item can be used for mornig sickness

A

Vit B6