Nausea And Vomitting Flashcards
What are some associated symptoms of nausea and vomiting ? (6)
- sweating and cold sweats
- increased saliva production
- headaches
- feeling cold
- going pale
- feeling weak
How can a toxic substance cause nausea and vomiting?
. Toxic substance stimulates the chemoreceptors trigger zone (CTZ) in brain.
. Vomiting centre in brainstem receives nerve signals from CTZ and other pathways e.g. gut, liver signals
.vomiting centre sends impulses to pharynx, larynx, gut etc to cause nausea and vomiting plus other symptoms.
What area some gastrointestinal causes of nausea and vomiting ?
. Food poisoning, acute appendicitis, GORD (gastro-oesophageal reflux disease ), blockage, overindulgence
What metabolic issues can lead to nausea and vomiting ?
Diabetic ketoacidosis- lack of insulin causing ketone levels to build up
hypercalemia -high calcium levels
Name some neurological causes of nausea and vomiting
Head injury, meningitis, migraine , stress
What type of ear disorders can cause nausea and vomiting
Conditions like labyrinthitis (inflammations of labyrinth- fluid channels in the ear) or ear infections
What psychiatric condition can cause nausea and vomiting ?
Bulimia nervosa
Nausea and vomiting in pregnancy :
- When does it begin ?
- When does it peak ?
- When does it usually resolve ?
1.Begins between week 4-7
- Peaks at weeks 9-16
- Resolves in weeks 16-20 , if it continues beyond this stage there may be an alternative cause
What is hyperemesis gravidarum and how is it treated
Hyperemesis gravidarum: extreme, prolonged vomiting and nausea during pregnancy , may experience weight loss and dehydration
Patients often given medication and admitted for IV fluids
What is hCG and how does it relate to nausea and vomiting
A hormone which is produced during pregnancy, hormone which is identified on pregnancy test.
Increased hCG levels -> increased nausea/ vomiting
What is the relationship between oestrogen in pregnancy and nausea and vomiting ?
Higher oestrogen levels-> increased nausea and vomiting
What is gastric dysfunction caused by during pregnancy?
Increased progesterone levels cause smooth muscle relaxation which impairs small bowel motility
(therefore delayed gastric emptying ) this can cause nausea/vomiting
How is motion sickness caused?
In near ear sends different signals to your brain from those your eyes are seeing, confusing message causes nausea
Which groups of people are most affected by motion sickness?
Women and children
When should we consider referral for patients who have nausea & vomiting? (5)
. Symptoms of heart attack e.g. chest pain, abdominal pain, shortness of breath
. Pregnancy
. Bilious vomiting- dark green indicates possible GI obstruction
. Suspected abdominal issue e.g. appendicitis
. Dehydration, especially if its a child
What is recommended to patients that are experiencing nausea and vomiting ?
. Stay hydrated - rehydration therpay may be recommended
. OCT antiemetics e.g. pepto-bismol .
Antiemetics: When can prochlorperazine be used to treat nausea and vomiting ?
- dopamine antagonist
- baccal tab ONLY prescribed for n&v when migraine/ headaches are present
- only given to patients 18 and older.
Antiemetics: What type of medication is hyoscine hydrobromide
Hyoscine hydrobromide is a travel sickness (motion sickness) medicine that belongs to a group of medicines called anticholinergics or antimuscarinics.
What brands are examples of hyoscine hydrobromide seen in first line treatment for n&v?
Kwells, Joy-Rides
Whats an example of a POM hyoscine hydrobromide ?
Scopoderm Patches
What can be the side affects of hyoscine?
Drowsiness , constipation, dry eyes
Antiemetics: what are some examples of sedating antihistamines used in travel sickness? (2)
. Cinnarizine - sturgeon
. Promethazine- phenergan
Whats an advantage and disadvantage of taking sedating antihistamines over hyoscines?
Sedating antihistamines are slightly less effective than hyoscines but they are better tolerated
What are some practical measures for n&v?
- fresh air
- distractions e.g. music
- regular sips of cold water
- ginger or peppermint tea
- ginger foods
- smaller, more frequent meals
- avoid strong smells
What measures can be taken to avoid motion sickness ?
- sit in front/middle of vehicle
- not reading/watching film
- look at fixed point ahead
- close eyes/sleep
- focus on your breathing
- fresh air from window
- avoid heavy meals/ alcohol
- break up long journeys to get fresh air
- antiemetics