Nature And Mechanism Of Mutation In Genome

Question 1

What are the 2 forms of stable DNA bases

Answer 1

Keto form and Amino form
Keto = T, G
Amino = A, C

Question 2

What are the two unstable forms of DNA bases

Answer 2

Enol T,G

Imino A,C

Question 3

In depurination rxns, what bond is cleaved when removing purine ring

Answer 3

N glycosidic bond

Question 4

What effect does base analogs have when incorporated into DNA

Answer 4

Increases likeliness of mispairing

Question 5

What are intercalating agents

Answer 5

Thin, platelike h.phobic molecules that insert themselves between adjacent bps. And are + charged

Question 6

Where can CpG islands be found on genome

Answer 6

5’ end of genes