Natural Hisotry Of Disease Flashcards
When does the preclinical phase begin in that natural history of disease?
Biological onset of disease
Pathologic evidence
Prognosis
Prediction of probable cure & outcome of a disease
Likelihood of recovery from a disease
When does the clinical phase begin in the natural history of the disease?
Medical care
Diagnosis
Treatment
Outcome
What are five ways of expressing prognosis?
Case fatality rate 5 year survival rate Observed survival rate Median survival rate Relative survival rate
In the 5 methods, what is the most accurate method?
Relative survival rate
Which prognosis method can we observe survival using life tables?
Observes survival rate
Which prognosis method is an age-adjustment for survival rates?
Relative survival rate
Which prognosis method is a measure of virulence?
Case fatality rate
Which prognosis method allows for calculation of only half the study population?
Median survival rate
Case fatality rate (CFR) formula
# of ppl who die from disease ---------------------------------- # of ppl w/disease
What does a CFR of 80% mean?
80% of ppl died from the disease out of the amount of ppl that had it
How do you calculate 5 year survival rate?
% of patients alive after 5yrs of treatment began
Is it possible to calculate 2 year survival rate?
Yes
What problem is associated with calculating 5 year survival and give example?
Screening, arbitrary, can miss ppl
What does the 5 year survival rate of 90% mean?
Treatment is very effective
What prognosis method improved upon the limitation of 5 year survival?
Observed survival
What is the median survival time?
Length of time that half the study population survives
Give two reasons why median survival time is preferred over mean survival time?
So data wouldn’t be screwed
Median is less effected
How does it improve upon observed survival rates?
Calculates probability of surviving each year
When to expect it to go down
Are survival data usually representative of the general pop? Why or why not?
No bc the data is often obtained from hospitals or other healthcare facilities
And patients may not be representative of the general pop
