nasal decongestant

Question 1

Pseudoephedrine - brand name

Answer 1

Sudafed

Question 2

pseudoephedrine - indication

Answer 2

relief of nasal congestion

Question 3

pseudoephedrine - MOA

Answer 3

stimulate:
alpha-adrenergic receptor -> vasoconstriction which leads to less vessel enlargement and mucosal edema

beta-adrenergic receptor -> some bronchial relaxation AND increase heart rate and contractiality

Question 4

pseudoephedrine - contraindication

Answer 4

hypersensitivity
recent MAO inhibitor use (14 days)

Question 5

pseudoephedrine - rare but serious reaction

Answer 5

heart palpitation
arrhythmias
increase blood pressure
*caution with uncontrolled cardiovascular disease, increase risk with constant use

Question 5

pseudoephedrine - common reaction

Answer 5

headache, insomnia, restlessness
nasal spray: local effects - stinging, sneezing, dry nose

Question 6

pseudoephedrine - counsel

Answer 6

AVOID NEAR BEDTIME
Nasal spary: dont use for more than 3 days (can cause rebound congestion)

Question 7

pseudoephedrine - alternatives

Answer 7

oxymetazoline (Afrin, others): OTC, nasal sprau