Narcotics - Lists Flashcards by Jesus Castro | Brainscape

Q

Good Oral Bioavailability

A

Codeine

Oxycodone

Levorphanol

Methadone

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Q

Crosses BBB

high lipophilicity

A

Heroin

Fentanyl/Sulfentanil

Buprenorphine

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Q

Anti-tussive

A

Codeine

Hydrocodone

Levorphanol (Levo form)

Levorphanol (Dextro form)

Dextromethorphan

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Q

Anti-diarrheal

A

Diphenoxylate (Lomotil)

Loperamide (Immodium)

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Q

Causes Seizures

A

Tramadol

Tapentadol

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Q

Cumulative Sedation and Respiratory Depression

A

Methadone

Levorphanol

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Q

Stimulates Cardiovascular System

Increases BP

A

Pentazocine

Butorphanol

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Q

Muscular Rigidity
(interferes with ventilators)
Used in Cardiac Surgery

A

Fentanyl

Sufentanyl

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Q

Withdrawal Symptoms

A

Pentazocine

Mu antagonists

Naloxone

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Q

Blocks 5HT reuptake

Serotonin Syndrome

A

Meperidine

Methadone

Levorphanol

Dextromethorphan

Tramadol

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Q

Blocks NE reuptake

A

Methadone

Levorphanol

Dextromethorphan

Tramadol

Tapentadol

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Q

Mu agonist

A

Tramadol

Tapentadol

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Q

Mu partial agonist

A

Pentazocine (mu antagonist)

Butorphanol

Buprenorphine

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Q

Mu antagonist

A

Pentazocine

Nalbuphine (potent)

Naloxone

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Q

Kappa agonist

A

Pentazocine (potent)

Butorphanol (potent)

Nalbuphene

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Q

Kappa antagonist

A

Buprenorphine (weak)

Naloxone

Q

Sigma Agonist

A

Dextromethorphan

Pentazocine (significant)

Q

Delta antagonist

A

Buprenorphine (weak)

Naloxone

Q

NMDA Antagonist

A

Methadone

Dextromethorphan

Q

Less potent than Morphine

A

(CHUMP)

Codeine

Hydrocodone

Tramadol (Ultram)

Meperidine

Propoxyphene