Narcolepsy Flashcards
0
Q
Siegel (REM hypothesis)
A
Recorded activity of neurons that normally only accompany rem sleep in dogs
1
Q
Vogel (REM hypothesis)
A
Observed REM sleep at the onset of sleep in a narcoleptic patient
2
Q
Honda (HLA)
A
Found increased frequency or HLA in narcoleptic patients
3
Q
Mignot (HLA)
A
HLA variant is not found in all narcoleptics so must be an explanations
4
Q
Mignot ( hyprocretin neurotransmitter)
A
It doesn’t run in families so not due to inherited factors
5
Q
Lin et al ( hyprocretin neurontransmitter)
A
Found a low levels of hyprocretin neurotransmitters in narcoleptic dogs due to mutation in a gene which was distrusting their productivity
