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More Drugs > Naplex > Flashcards

Naplex Flashcards

1
Q

Schilling test

A

Tests for pernicious anemia-b12 anemia from lack of intrinsic factor

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2
Q

D dimer

A

Tests for blood clot

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3
Q

Coombs test

A

Tests for hemolytic anemia DRUG INDUCED

POSITIVE IN: PCN/cephalosporins, levodopa, methyldopa, quinidine, rifampin, sulfonamides

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4
Q

Epogen

A

Epoetin alpha- for anemia

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5
Q

Procrit

A

Epoetin alpha- for anemia

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6
Q

Aranesp

A

Darbepoetin- for anemia. Longer half life

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7
Q

Eltrobopag

A

Promacta-for aplastic anemia- helps bring up platelets

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8
Q

Promactra

A

Eltrombopag- aplastic anemia

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9
Q

Beclomethasone

A

Qvar

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10
Q

Symbicort

A

Budesonide and formoterol

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11
Q

Arnuity ellipta

A

Fluticasone

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12
Q

Advair

A

Fluticasone and salmeterol

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13
Q

Beep ellipta

A

Fluticasone and vilanterol

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14
Q

Dulera

A

Momestasone and formoterol

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15
Q

Alvesco

A

Ciclesonide- ics

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16
Q

Serevent

A

Salmeterol

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17
Q

Pulmocort

A

Budesonide

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18
Q

Asmanex

A

Mometasone

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19
Q

HFA

A

MDI

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20
Q

Respimat

A

MDI

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21
Q

No suffix

A

MDI

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22
Q

Diskus

A

DPI

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23
Q

Ellipta

A

DPI

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24
Q

Pressair

A

DPI

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25
Q

Handihaler

A

DPI

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26
Q

Neohaler

A

DPI

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27
Q

Respiclick

A

DPI

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28
Q

Flexhaler

A

DPI

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29
Q

Zafirlukast

A

Leukotriene antagonist

Accolate

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30
Q

Zileuton

A

Leukotriene antagonist

Zyflo

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31
Q

Omalizumab

A

Xolair

Allergic Asthma

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32
Q

Nucala

A

Mepolizumab

Interleukin antagonist for asthma

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33
Q

Cinqair

A

Reslizumab

Interleukin antagonist for asthma

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34
Q

Fasenra

A

Benralizumab

Interleukin antagonist for asthma

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35
Q

Dupixent

A

Dupilumab

Interleukin antagonist for asthma

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36
Q

Atrovent

A

Ipratropium-

SAMA

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37
Q

Combivent

A

Atrovent (ipratropium)

Plus albuterol

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38
Q

Roflumilast

A

Daliresp
Pde4 inhibitor
Asthma

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39
Q

Hydroxyurea

A

Droxia, Hyderabad, siklos
Sickle cell dx
Stimulates production of hemoglobin f

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40
Q

Endari

A

L-glutamine
Sickle cell dx
Reduces oxidative stress

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41
Q

Stress test drugs

A

Dipyridamol, adenosine (adenoscan), regadenoson (lexiscan), or dobutamine

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42
Q

Yosprala

A

Aspirin/omeprazole

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43
Q

Ranexa

A

Ranolazine- SIHD

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44
Q

Reopro

A

Abcixinab
GpIIaIIIb inhibitor
PCI only
Needs filter

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45
Q

Integrillin

A

Eptifibatide

GpIIbIIIa inhibitor

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46
Q

Aggrastat

A

Tirofiban

GoIIbIIIa inhibitor

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47
Q

Zontivity

A

Vorapaxar
Pat-1 blocker
ACS

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48
Q

Corlanor

A

Ivabradine
Funny channel blocker
Decrease HR for HF

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49
Q

Adenosine

A

Paroxysmal supraventricular tachyarrythmka (psvt)

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50
Q

Symbyax

A

Fluoxetine + olanzapine

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51
Q

Vytorin

A

Simvastatin + ezetimibe

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52
Q

Zyban

A

Bupropion for smoking

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53
Q

Contrave

A

Bupropion + naltrexone for weight loss

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54
Q

Quillichew/quillivant

A

Methylphenidate

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55
Q

Cotempla

A

Methylphenidate odt

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56
Q

Dantrolene

A

EPS
Ryanodex, dantrium, revonto
NMS!!

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57
Q

Nuplazid

A

Pimavanserin

Psychosis with Parkinson’s

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58
Q

Valbenazine

A

Tardive dyskinesia

Ingrezza

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59
Q

Deutetrabenazine

A

Huntington’s and TD

Austedo

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60
Q

Belsomra

A

Suvorexant
Orexin blocker
Sleep

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61
Q

Silenor

A

Doxepin

Sleep

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62
Q

Horizant

A

Gabapentin enacarbil

Post herpetoc neuralgia + restless leg syndrome

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63
Q

Sodium oxybate

A 
Xyrem 
Narcolepsy 
Helps you sleep at night
Date rape drug
C3
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64
Q

Apokyn

A

Apomorphine
Rescue for Parkinson’s
Causes severe hypotension &n/v, retching , qtc

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65
Q

Tigan

A

Trimethobenzamide

Prevent Emesis with apomorphine- give 3 days prior (can’t give 5ht3 blockers- causes hypotension)

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66
Q

Amantadine

A

Blocks dopamine reuptake

Treats dyskinesias associated with peak dose of sinemet

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67
Q

Zelapar

A

Selegiline
Mao b blocker
PD

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68
Q

Azilect

A

Rasagiline
Mao b blocker
PD

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69
Q

Xadago

A

Safinamide
Mao b blocker
PD
Hepatic impairment

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70
Q

Northera

A

Droxidopa

Hypotension in PD

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71
Q

Neupogen

A

Filgrastim
CSF
White blood cell growth factor

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72
Q

Neulasta

A

Peggilgrastim
CSF
WBC growth factor

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73
Q

Hyaluronidase

A

Extravasation with vinca alkaloids and etoposide

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74
Q

Toltect

A

Dexrazoxane

Anthracycline extravasation

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75
Q

Zometa

A

Zolendronate for hypercalcemia in malignancy

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76
Q

Xgeva

A

Denosumab
Hypercalcemia malignancy
MAb
Blocks interaction of RANKL and RANK

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77
Q

Reclast

A

Zolendronate

Osteoporosis

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78
Q

Prolia

A

Denosumab

Osteoporosis

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79
Q

Miacalcin

A

Calcitonin

Hypercalcemia in malignancy

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80
Q

Tumor lysis syndrome treatment

A

High dose allopurinol

Rasburicase it reaction with allopurinol

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81
Q

Emend

A

Aprepitant

Antiemetic

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82
Q

Sancuso

A

Granisetron

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83
Q

Aloxi

A

Palonosetron

Long half life

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84
Q

Decadron

A

Dexamethasone

Antiemetic

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85
Q

Zinecard

A

Dexrazoxane

Cardioprotective with doxorubicin

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86
Q

Mesnex

A

Mesna

With ifosfamide or cyclofosfamide to prevent hemmoragic cystitis

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87
Q

Fusilev

A

Leucovorin
With mtx it reduced myelosuppression
With 5FU it enhances efficacy

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88
Q

Ethyol

A

Amifostine

With cisplatin to prevent nephrotoxicity

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89
Q

Akynzeo

A

Netupitant + palonosetron

Antiemetic

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90
Q

Herceptin

A

Trastuzumab
HER2 blocker
Her2 overexpression in breast cancer
Can cause HF

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91
Q

Faslodex

A

Fulvestrant

SERM breast cancer

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92
Q

Evista

A

Raloxifene
SERM
Breast cancer PROPHYLAXIS NOT TREATMENT
Osteoporosis prevention

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93
Q

Arimidex

A

Anastrazole
Aromatase Inhibitor
Postmenopausal breast cancer

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94
Q

Femara

A

Letrozole
Aromatase inhibitor
Post menopausal breast cancer

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95
Q

Aromasin

A

Exemestane
Aromatase inhibitor
Post menopausal breast cancer

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96
Q

Lupron

A

Leuprolide
GnRH agonist
Prostate cancer

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97
Q

Zoladex

A

Goserelin
GnRH agonist
Prostate cancer

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98
Q

Casodex

A

Bicalutamide
Antiandrogen
Given with GnRH agonist to prevent tumor flare

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99
Q

Cyclophosphamide

A

Alkylating agent

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100
Q

Ifosfamide

A

Alkylating agent

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101
Q

Carmustine

A

Alkylating agent

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102
Q

Busulfan

A

Alkylating agent

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103
Q

Cisplatin

A

Platinum
100 mg/m2/cycle
Highly emetogenic

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104
Q

Carboplatin

A

Platinum

Dosed on Calvert formula not BSA

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105
Q

Doxorubicin

A 
Anthrcycline
450-550 mg/m2/lifetime
Central line
Give with zinecard for heart protection
Or totect for extravasation
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106
Q

Mitoxandrone

A

Anthracycline

Blue urine

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107
Q

Vincristine

A

Vinca alkaloid
Do NOT GIVE INTRATHECAL
Warm NOT cold compress for extravasation with vincas

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108
Q

Vinblastine

A

Vinca alkaloid

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109
Q

Paclitaxel

A

Taxane

Premedication (unless albumin bound)

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110
Q

Docetaxel

A

Taxane

Premedication

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111
Q

Irinotecan

A

Topoisonerase 1 inhibitor
Give with atropine to prevent diarrhea
Loperamide at home

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112
Q

Bleomycin

A

Topoisomerase 2 inhibitor
Pulmonary toxicity max 400 units/life
Not mylosupressive

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113
Q

Etoposide

A

Topoisomerase 2 inhibitor

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114
Q

Fluorouracil

A

Antimetabolite

5FU

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115
Q

Capecitamine

A

5FU prodrug
Antimetabolite
Xeloda
Take with food

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116
Q

Glucarpidase

A

Voraxaze

Rapidly lowers MTX levels when they are high despite hydration and urine alkalizatjkn

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117
Q

X(lidomide)

A

Immunodulators
REMS
Severe birth defects

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118
Q

Avastin

A

Bevacizumab

VegF blocker

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119
Q

Ceruximab

A

Erbitux
EGFR inhibitor
Need EGFR expression and KRAS wild type
Acneiform rash

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120
Q

Rituximab

A 
Rituxan
Premedication needed- infusion reaction
Cancer
Can cause PML
CD20 positive
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121
Q

Gleevec

A 
Imatinib 
Tyrosine kinase inhibitor
Pharmacogenomic testing 
Take with food
Must be Philadelphia chromosome positive BCR-ABL
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122
Q

Activase

A

Alteplase

Fibrinolytic

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123
Q

Tenecteplase

A

Tnkase

Fibrinolytic

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124
Q

Retavase

A

Reteplase

Fibrinolytic

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125
Q

Viread

A

TDF

Nrti- HBV

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126
Q

Vemlidy

A

TAF

Nrti-hbv

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127
Q

Altoprev

A

Lovastatin

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128
Q

Lopid

A

Gemfibrozil

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129
Q

Antara

A

Fenofibrate

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130
Q

Trillpix

A

Fenofibrate

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131
Q

Lovaza

A

Omega 3 ethyl esters

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132
Q

Vascepa

A

Icosapeny ethyl

Fish oil

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133
Q

Multaq

A

Dronedarone

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134
Q

Dulera

A

MDI

Don’t put in water!

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135
Q

Symbicort

A

MDI

Don’t put in water!

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136
Q

Protamine

A

UFH antidote
1 mg reverses 100 units of heparin (only reverse heparin given in last 2-2.5 hrs)
Max dose is 50 mg
For LMWH: 1 mg per 1 mg, can give for doses in last 8 hrs

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137
Q

Andexxa

A

Andexanet

Antidote for rivaroxaban and apixaban

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138
Q

Arixtra

A

Fondaparinux
10a inhibitor
SubQ
Acts similar to heparins

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139
Q

Idaricizumab

A 
Praxbind
Dabigatran (pradaxa) antidote
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140
Q

Angiomax

A

Bivalrudin
Cardiac cath lab
Safe in HIT
Direct thrombin inhibitor

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141
Q

Argatroban

A

Direct thrombin inhibitor

Safe in hit (preferred)

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142
Q

Mephyton

A

Vitamin K

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143
Q

Kcentra

A

PCC
Warfarin OD, bleeding required
Give with IV vitamin k 5-10 mg

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144
Q

Namzaric

A

Memantine + donepezil

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145
Q

Zarontin

A

Ethosuximide

Absence seizures

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146
Q

Carntine

A

Hyperammonemia with valproate

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147
Q

Vimpat

A

Lacosamide
C-V
Epilepsy

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148
Q

Cerebyx

A

Fospehnytoin

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149
Q

Marplan (isocarboxazid)

A

Non selective Mao inhibitor

Depression

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150
Q

Nardil

A

Phenelzine
Non selective Mao inhibitor
Depression

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151
Q

Parnate

A

Trancypromine
Non selective Mao inhibitor
Depression

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152
Q

Neupro-rotigotine

A

DA
PD
Patch

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153
Q

Rivaatigmine

Exelon

A

Alzheimer’s
Patch
Ach esterase inhibitor

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154
Q

Avelox

A

Moxifloxacin

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155
Q

Invanz

A

Ertapenem

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156
Q

Fortaz

A

Ceftazidime

3rd gen group 2

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157
Q

Maxipime

A

Cefepime

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158
Q

Cubicin

A

Daptomycin

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159
Q

Zyvox

A

Linezolid

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160
Q

Colistimethate sodium

A

Polymixin abx

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161
Q

Dificid

A

Fidaxomicin

Cdif

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162
Q

Ambisome

A

Amphotericin B lipid formulation

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163
Q

Ancobon

A

Flucytosine

5-FC

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164
Q

Vfend

A

Voriconazole

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165
Q

Noxafil

A

Posaconazole

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166
Q

Cancidas

A

Caspofungin

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167
Q

Mycamine

A

Micafungin

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168
Q

Foscarnet

A

Treats acyclovir resistant genital herpes

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169
Q

Resistant CMV

A

Foscarnet and cidofovir

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170
Q

Accolate

A

Zafiukast

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171
Q

Mycelex

A

Clotrimazole

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172
Q

Griseofulvin

A 
Antifungal
Bonds keratin precursor cells
Dematomycosis and tinea infections of skin hair nails
Take with fatty meal
Photo sensitivity
Lfts 
CI in pregnancy
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173
Q

Sporanox

A

Itraconazole

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174
Q

Nizoral

A

Ketoconazole

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175
Q

Xofluza

A

Baloxavir marboxil
Flu
Single dose regimen

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176
Q

Relenza

A

Zananivir
Diskhaler
Older than 7
No lung issues

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177
Q

Cytovene

A

Ganciclovir

CMV

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178
Q

Valcyte

A

Valganciclovir

CMV

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179
Q

Norvir

A

Ritonovir

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180
Q

Chemo drugs that don’t cause myelosuppression

A

Bleomycin, vincristine, asparaginase, TKIs, MAbs

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181
Q

Chemo with most nausea

A

Cisplatin, cyclophosphamide, ifosfamide

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182
Q

Chemo mucositis

A

F5U, MTX

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183
Q

Chemo diarrhea

A

Irinotecan, capecitabine, 5FU, MTX

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184
Q

Chemo constipation

A

Vincristine

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185
Q

Chemo cardiotoxicity

A

Anthracyclines, arsenic, TKIs

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186
Q

Chemo pulmonary

A

Bleomycin, busulfan, carmustine, Lomisttine

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187
Q

Chemonephrotoxicirt

A

Cisplatin, MTX

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188
Q

Chemo neuropathy

A

Vincas, platinums, taxanes

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189
Q

Chemo neurotoxicity

A

Nitrosoureas (lomistine, carmustine)

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190
Q

Febrile neutropenia temp

A

> 101 x 1
100.4 for more than an hour
Need pseudomonas coverage

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191
Q

Dimethyl sulfoxide

A

Anthracycline extravasation

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192
Q

Karnofsky and ECOG

A

Measure physical functioning in cancer patients

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193
Q

BRCA mutation

A

Increases risk of breast cancer

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194
Q

Xeloda

A

Capecitabine

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195
Q

Everolimus

A

Mtor inhibitor
VegF
Mouth ulcers, rash, interstitial lung dx

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196
Q

Vaccines to separate from immunoglobulins

A

Varicella, not zoster
Mmr
Note: separate all live from tb test

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197
Q

Harvix

A

HepA vaccine

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198
Q

VAQTA

A

HepA vaccine

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199
Q

Adacel

A

Tdap

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200
Q

Boostrix

A

Tdap

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201
Q

SubQ vaccines

A

MMR, MMRV, varicella, zostavax, yellow fever

Ppsv23 can be IM or subQ

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202
Q

Vaccines in freezer

A

Varicella, zostavax, mmrv, mmr optional, oral cholera

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203
Q

Vaccines with antiviral interaction

A

Varivax and zostavax, stop antivirals 24 hours before and 14 days after
Also don’t give with gelatin or neomycin

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204
Q

Fragmin

A

Dalteparin

Lmwh

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205
Q

Savaysa

A

Edoxaban

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206
Q

Bevyxxa

A

Betrixaban

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207
Q

Retrovir

A 
Zidovudine
Nrti 
Myopathy
Macrocytic anemia
Used in labor of hiv infected pregnant women
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208
Q

Prandin

A

Repaglinide secretagogues

Before meals meglitinides

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209
Q

Starlix

A

Nateglinide
Meglitinides

Before meals
Secretegogue

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210
Q

Glucotrol

A

Glipizide

With meal

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211
Q

Amaryl

A

Glineperide

With meal

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212
Q

Glynase

A

Glyburide

With meal

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213
Q

Avandia

A

Rosiglitazone

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214
Q

Steglarto

A

ErtuglifloZin

Sglt2 inhibitor

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215
Q

Farxiga

A 
Dapagliflozin
Bladder cancer(pioglitazone too)
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216
Q

Invokana

A

Increase k+

Amputations

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217
Q

Nesina

A

Aloglitptin

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218
Q

Glyset

A

Miglitol
Alpha glucosidase
With food

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219
Q

Precose

A

Acarbose
Alpha glucosidase
With food

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220
Q

Cycloset

A

Bromocriptine
DM
Dopamine agonist

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221
Q

Adlyxin

A

Licisenatide

Glp1

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222
Q

Saxenda

A

Liraglutide for weight loss

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223
Q

Glp1 issues

A

Thyroid cancer
Pancreatitis (DPP4 too)
Don’t use with gastroparesis
Byetta/bydureon don’t use in crcl less than 30

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224
Q

Sylmlin

A 
Pramlintide
Give before meals
Amylin analog
Hypoglycemia
Can use in type 1 and 2
Decrease prandial insulin by 50%
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225
Q

Concentrated insulin

A

Humalog kwikpen 200u/ml (not always)

Humulin r u-500 500/ml

Tresiba (degludec) 200/ml

Toujeo (glargine) 300/ml

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226
Q

Apidra

A

Glulisine

Rapid acting

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227
Q

Fiasp

A

Aspart

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228
Q

Tresiba

A

Degludec

Can be 100 or 200 units/ml

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229
Q

Toujeo

A

Glargine

Only 300 units/ml

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230
Q

Insulin to carb ratio

A

Rapid acting: 500/TDD

Regular: 450/TDD

Tells how many carbs are covered by 1 unit

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231
Q

Correction factor

A

Rapid acting: 1800/TDD

Regular: 1500/TDD

Tells how much 1 unit will drop the glucose by

Dose= (glucose-target glucose)/CF

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232
Q

Tapazole

A

Methimazole
Hyperthyroid
For pregnancy use in last two trimesters

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233
Q

Cytomel

A

Liothyronine

Hypothyroid

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234
Q

Propylthiouracil

A

PTU
Hyperthyroidism
For pregnancy use in 1st trimester

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235
Q

Lugols and sski

A

Hyperthyroidism

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236
Q

Thyroid storm

A

PTU+sski/lugols+propranolol+dexamethasone and cooking

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237
Q

Fludrocortison

A

Mineralocorticoid
Addisons
Off label for orthostatic hypotension

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238
Q

Otrexup

A

Mtx

Autoinjector

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239
Q

Rasuvo

A

Mtx

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240
Q

Xatmep

A

Mtx

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241
Q

Hydroxychloroquine

A 
RA
Nonbiologic DMARDs 
Or lupus 
Use with or instead of mtx when worried about liver Dx
Eye damage-irreversible
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242
Q

Azulfidine

A

Sulfasalazine

RA

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243
Q

Sulfazalazine

A 
RA
Sulfa allergy
Yellow/orange skin/urine
Salicylate allergy
Liver damage
Alopecia
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244
Q

Arava

A

Leflunomide
TA
Fetal toxicity -neg pregnancy test and two BC- wait 2 years before getting pregnant
Hepatotoxicity

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245
Q

Xeljanz

A

Tofacitinib

Non biological DMARDs

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246
Q

Olumiant

A

Baricitonib

Non biological DMARDs

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247
Q

Mtx

A

No etoh allowed-liver damage

Non biological DMARDs

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248
Q

Enbrel

A

Eterecept
Weekly
TNF

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249
Q

Humira

A

Adalimumab
QOweek
TNF

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250
Q

Cimzia

A 
Certilizumab
QOweek
Biological DMARDs 
TNF
45 degree angle (90 for others)
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251
Q

Simponi

A

Golimumab
Biological DMARDs
Monthly
TNF

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252
Q

Infliximab

A 
Remicade
biological DMARDs 
IV
Filter
Premedication
Delayed hypersensitivity rxn 
Insidious rxn 
NS only
TNF
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253
Q

Rituxan

A 
Rituximab
CD20 
Non TNF biological DMARDs
Premedicate! Must! Fatal infusion rxn 
IV
SJS/TEN
Hep B reactivation
PML!
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254
Q

Kineret

A

Anakinra

Non TNF biological DMARDs

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255
Q

Orencia

A

Abatacept

Non TNF biological DMARDs

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256
Q

Actemra

A

Tocilizumab

Non TNF biological DMARDs

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257
Q

Kevzara

A

Sarilumab

Non TNF biological DMARDs

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258
Q

Benlysta

A

Belimumab

SLE

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259
Q

Copaxone

A

Glatiramer
MS
Safe in pregnancy

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260
Q

Interferon beta

A

MS
Alpha is for hepatitis
Plegridy-pegylated interferon

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261
Q

Fingolumab

A

Gilenya
MS
Bradycardia -monitor for 6 hrs
PO

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262
Q

Teriflunamide

A

MS
Fetal toxicity
Aubagio
PO

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263
Q

Tecfidera

A

Dimethyl fumarate
MS
PO

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264
Q

Tysabri

A

Natalizumab MS

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265
Q

Lemtrada

A

Alemtuzumab
MS
REMS

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266
Q

Ocrevus

A

Ocrelizumab

MS

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267
Q

Mavenclad

A

Cladribine

MS

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268
Q

Restasis

A

Cyclosporine eye drop
Sjogrens
Beware eye infections

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269
Q

Cevimeline

A

Evoxac

Dry mouth

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270
Q

Salagen

A

Pilocarpine

Dry mouth

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271
Q

Lumigan

A 
Bimatoprost
Prostaglandin analog (also in lattisse ( don’t use lattisse with other PROstaglandin)
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272
Q

Travatan

A

Travaprost

Prostaglandin analog

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273
Q

Xelpros

A

Latanaprost

Prostaglandin analog

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274
Q

Cosopt

A

Timolol +dorzolamide

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275
Q

Vigamox

A

Moxifloxacin eyedrops

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276
Q

Maxitrol

A

Neomycin/polymyxin/dexamethason eye drops

Conjunctivitis

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277
Q

Ocuflox

A

Ofloxacin eye drop

Pink eye

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278
Q

Polytrim

A

Trimethoprin/polymyxin eye drops

Pink eye

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279
Q

Acular

A

Ketorlac eye drop

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280
Q

Dry eye

A

Refresh, systane

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281
Q

Visine

A

Tetrahydrozoline

Red eyes

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282
Q

Red eyes

A

Naphazoline, visine

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283
Q

Ciprodex

A

Ciprofloxacin and dexamethasone ear drops for otitis

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284
Q

Triethanolamine

A

Ear wax removal

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285
Q

Rhinocort

A

Budesonide

Preferred in pregnancy

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286
Q

Nasocort

A

Triamcinolone

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287
Q

Dorzolamide

A

Carbonic anhydride inhibitor

Reduce production

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288
Q

Brimonidine

A

Alpha 2 agonist
Increase outflow
And reduce production

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289
Q

Timolol eye drop

A

Reduce production

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290
Q

Differin (adapalene)

A

Topical retinoids

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291
Q

Topical dapsone

A

Acne

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292
Q

Solodyn

A

Minocycline

Acne

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293
Q

Propecia

A

Finasteride for alopecia

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294
Q

Proscar

A

Finasteride for BPH

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295
Q

Nizoral

A

Ketoconazole shampoo

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296
Q

Desitin

A

Diaper rash

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297
Q

Elidel

A

Pimecrolimus
Calcineurin inhibitor
Eczema

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298
Q

Protopic

A

Tacrolimus topical
Calcineurin inhibitor
Eczema

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299
Q

Eucrisa

A

Crisaborole

Eczema

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300
Q

Dupixent

A

Dupilimab

Eczema

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301
Q

Lamisil

A

Terbinifine

Lamisil AT is topical form

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302
Q

Lotrimin

A

Butenafine

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303
Q

Lotrisone

A

Betamethasone and clotrimazole

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304
Q

Onychomycosis

A

Terbinafine or itraconazole

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305
Q

Aldara

A

Imiquimod cream

Genital warts

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306
Q

Pyrantel pamoate

A

Pinworm

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307
Q

Permethrin

A

Nix
Lice/scabies-rx
Repeat on day nine for lice

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308
Q

Pyrethrin/piperonly butoxide

A

Lice
RID
Repeat on day nine

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309
Q

Steroid vehicle potency

A

Ointment>cream>lotion>solution>gels>sprays

310
Q

Flolan

A

Epoprostenol

311
Q

Remodulin

A

Treprostinil
PAH
Prostacyclin

312
Q

Tyvaso

A

Inhaled treprostinil
PAH
Prostacyclin

313
Q

Ventavis

A

Iloprost
PAH
Prostacyclin

314
Q

Uptravi

A

Selexipag
PAH
Tablet
Prostacyclin

315
Q

Tracleer

A

Bosentan
Endothelin receptor blocker
REMs

316
Q

Letairis

A

Ambrisentan
ERA
Helatitoxicity( others too)
REMs

317
Q

Opsumit

A

Macitentan
ERA
Hepatoxic, teratogenic (others too)
REMs

318
Q

Revatio

A

Soldenafil

PAH

319
Q

Adcirca

A

Tadalafil

PAH

320
Q

Adempas

A 
Riociguat
PAH
Soluble guancylate Cyclase stimulator
Lots of DI
No pregnancy 
REMs
321
Q

Riociguat

A 
Adempas
PAH
REMs
No pregnancy
Lots of DI
322
Q

When to treat BP in pregnancy

323
Q

Lotrel

A

Benazepril + amlodipine

324
Q

Ziac

A

Bisoprolol + hctz

325
Q

Tenorectic

A

Atenolol + chlorthalidone

326
Q

Zestorectic

A

Lisinipril + hctz

327
Q

Hyzaar

A

Losartan + hctZ

328
Q

Maxide, dyazide

A

Triamterine + hctz

329
Q

Cozaar

330
Q

Lotensin

A

Benazapril

331
Q

Vasotec

332
Q

Altace

333
Q

Tekturna

334
Q

Inspra

A

Eplerenone

335
Q

Dyrenium

A

Triamterine

336
Q

Brevibloc

337
Q

Clonidine patch

A

Kapvay

Weekly patch

338
Q

Absorica

A

Isotretinoin
2 negative pregnancy tests
1 month before and after dont get pregnant
2 forms of BC

339
Q

Lysine

A

Natural predict to test and prevent cold sores

340
Q

Tinactin

A

Tolnaftate

341
Q

Ivermectin

A

Sklice

Lice

342
Q

Doryx

A

Doxycycline given before travel

343
Q

Typhim

A

Typhoid IM. Inactivated. 2 weeks before expected exposure

344
Q

Amethyst

A

Contraceptive

Continuous contraceptive

345
Q

Droseperinone containment COC

A

Yasmin, yaz

346
Q

POP

A

Camila, Erin, Nora-BE

347
Q

Do not use estrogen

A 
Breast, ovarian, liver cancer!
DVT/PE/stoke
BP>160/100
Migraines with aura!
DM
Unexplained uterine bleeding
Post pardom/breast feeding
Technivie and viekira pak- liver toxic
348
Q

Heavy menstruation

A

COC natazia

IUD mirena

349
Q

Premenstrual dysphoric disorder

A

Yaz, or antidepressant

350
Q

Drosperinone

A

K+ sparring diuretic
Higher clot risk
Less bloating
Can use continuous to help mood swings

351
Q

Medroxyprogesterone Injection

A

Decreases BMD

No DI

352
Q

Prezista

A

Darunavir

Sulfa allergy

353
Q

Maraviroc

A

Selzentry
CCR5 blocker
HIV

354
Q

Atelvia

A

Risendronate
Requires acidic gut-no PPI
Can take with food

355
Q

Boniva

A

Ibandronate
Monthly
IV is every 3 months

356
Q

Actonel

A

Risendronate

357
Q

Forteo

A

Teriparatide

Osteoporosis

358
Q

Abaloparatide

A

Tymlos

Osteoporosis

359
Q

Brisdelle

A

Paroxatine for vasomotor symptoms

360
Q

Stendra

A

Avanafil

On demand dosing

361
Q

Addyi

A 
Filbanserin
REMs
Hypotension
CI with alcohol
Requires medguide!
Premenopausal only
362
Q

Atelvia

A

Risendronate DR

Needs acid no acid suppressive

363
Q

Herbals for ED

A

L-arginine, panax ginseng, yohimbe

364
Q

Herbals for menopause

A

Evening primrose, soy, black cohosh, red clover

365
Q

BPH herbals

A

Saw palmetto, pygeum

They are not recommended

366
Q

Lycopene

A

Natural product used to prevent prostate cancer

367
Q

Uroxatral

A

Alfuzosin
Alpha blocker
Qt prolongation

368
Q

Jalyn

A

Tamsulosin + dutasteride

369
Q

Rapaflo

A

Silodosin
Alpha blocker
Retrograde ejaculation

370
Q

Cardura

371
Q

Tadalafil

A

Can be used for BPH at 5 mg daily

372
Q

Toviaz

A

Fesoterodine
Anticholinergic for OAB
M3 selective

373
Q

Vesicare

A

Solifenacin

M3 selective

374
Q

Oxytrol

A

Oxybutynin patch

Twice weekly

375
Q

Order to take CF meds

A

Bronchodilator> hypertonic Salome > forbade alpha > chest physiotherapy > inhaled antibiotics

376
Q

Pulmozyme

A

Dornase alpha
Do not mix with other drugs in nebulizer
Cf
Protect from light

377
Q

Viokace

A

Pancreatic enzyme
Lipase: <2500units/kg/meal or <10,000units/kg/meal
ONLY ONE THATS A TABLET
MUST GIVE WITH PPI!!

378
Q

Zenpep

A

Pancreatic enzyme
Lipase: <2500 units/kg/meal
Or <10000 units/kg/day

379
Q

Ivacaftor

A 
Kalydeco 
CF
>1 y/o
NOT for F508del
Helps channel stay open longer
380
Q

Orkambi

A

Lumacaftor/ivacaftor
F508del- protein FOLDING
>2 y/o

381
Q

Symdeko

A

Tezacaftor/ivacaftor
F508del- FOLDING mutation
>12 y/o

382
Q

Avodart

A

Ditasteride

383
Q

Enablex

A

Darifenacin

M3 selective

384
Q

Desmopressin

A

Nocturia

Adh

385
Q

Demeclocyline

A

Isovolemic hyponatremkia. May be d/t siadh

386
Q

Conivaptan

A

Vasopressin antagonist
Isovolemic and hypervolemic hyponatremia
Vaprisol

387
Q

Tolvaptan

A

Vasopressin antagonist
Samsca
Isovolemic and hypervolemic hyponatremia
Hepatotoxicity

388
Q

Sodium correction speed

A

Less than 12meq/L over 24 hours

Or osmotic demyelination syndrome

389
Q

Samsca

A

Tolvaptan
Vasopressin antagonist
Isovolemic and hypervolemic hyponatremia

390
Q

Desmopressin

A

Isovolemic hypernatremia

Bedwetting in children give tablets

391
Q

Carimune NF

392
Q

Flebogamm DIF

393
Q

Gammagard

394
Q

Gamunex c

395
Q

Octagam

396
Q

Privigen

397
Q

APACHE II

A

Mortality risk score for critical care patients

398
Q

Dopamine

A

Dose related receptor effects: 1-4 mcg/kg/min DA-1

5-10 mcg/kg/min: beta-1

10-20 mcg/kg/min: alpha-1

399
Q

Epinephrine

A

Alpha-1, beta-1, beta-2

400
Q

Norepinephrine

A

Alpha-1 > beta-1

Drug of choice for septic shock

401
Q

Phentolamine

A

Vasopressor extravasation

Alpha-1 blocker

402
Q

Nitroglycerin

A

Low doses venous, high doses arteries
Sorption(non pvc)
Tachyphylaxis- tolerance

403
Q

Nitroprusside

A

Nitropress, nitropride
Equal vein and artery
Blue means cyanide
Light protection

404
Q

Dobutamine

A

Positive ionotrope
Beta-1 agonist
CHF exacerbation

405
Q

Milrinone

A

PDE-3 inhibitor
Positive ionotrop
Vasodilator
CHF exacerbation

406
Q

RASS

407
Q

Delirium only ICU

A

Quetiapine is preferred and sedate with non-BZD

408
Q

Diprivan

409
Q

Lorazepam

A

Propylene glycol metabolite- bad for AKI and metabolic acidosis

410
Q

Stress ulcer prophylaxis

A

Mechanical ventilation (>48hours) and coagulopathy

411
Q

Quelicin

A

Succinylcholine

412
Q

Nimbex

A

Cisatracirium

413
Q

Cyklokapron

A

Tranexamic acid IV

Hemostatic agent

414
Q

Lysteda

A

Tranexamic acid tablet
Hemostatic agent
Heavy menstruation

415
Q

Novoseven RT

A

Recombinant factor VIIa

416
Q

Amicar

A

Aminocaproic acid

Hemostatic agent

417
Q

Fever when to refer

A

<3 months: 100.4
3-6 months: 101
>6 month: 103
All recital

418
Q

Apgar

A

Determines if baby is healthy or needs referral. Healthy is 7+

419
Q

Virazole

A

Ribavirin
RSV
Only for very severe cases!

420
Q

Synagis

A 
Palivizumab
RSV prophylaxis
High risk only
Q30 days throughout the treatment
Preterm or preterm with lung dx, heart conditions
421
Q

Palivizumab

A 
Synagis
RSV prophylaxis
Only high risk pts
Every 30 days during season
Preterm on 1st month or preterm with lung dx, heart conditions
422
Q

Croup

A

Dexamethasone, racemic nebulized epinephrine (severe)

423
Q

Simulect

A

Basiliximab
Induction immunosupression for transplant
IL-2 blocker

424
Q

Atagam, thymoblobulin

A

Antithymocyte globulin

Induction immunosupression transplant

425
Q

Maintanence immunosupression

A 
Prednisone
Mycophenolate (cellcept, myfortic)
Azathioprine
Tacrolimus (prograf-Calcinierin inhibitor)
Cyclosporine (modified: Gengraf, neoral)
Non modified: sandimmune
Everolimus (zortress, afintor)
Sirolimus (rappamune)
Belatacept (nulojix)
426
Q

Imuran

A

Azathioprine
Transplant
Myelosuppression

427
Q

Hydroxocobalamin

A

Reduce risk of thiocyanate toxicity with nitroprusside

428
Q

Sodium thiosulfate

A

Cyanide toxicity from nitroprusside

429
Q

Lithium conversions

A

5mL =8mEq

8mEq=300 mg

430
Q

Lithium therapeutic range

A

0.6-1.2 mEq/L

431
Q

Weight loss herbals

A

Bitter orange, caffeine, guarana, green tea

432
Q

Contrave

A

Naltrexone + bupropion

Avoid in: HTN, young adults/kids, seizures, on opioids

433
Q

Belviq

A

Lorcaserin

Weight loss, c4

434
Q

Qysmia

A 
Phentermine + topiramate
C4
REMs
Don’t use in: HTN, seizures
5HT2C agonist
Priapism, hypoglycemia
435
Q

Xenical

A

Orlistat
RX
MV away from this med bc fat soluble vits won’t absorb
Separate from levo and cyclosporin

436
Q

Alli

A

Orlistat
OTC
Separate from MV because fat soluble MV won’t be absorbed
Separate from Levo and cyclosporine

437
Q

Caldolor

A

IV ibuprofen

438
Q

Vimovo

A

Esomeprazole + naproxen

439
Q

Celecoxib

A

Sulfonamide allergy

440
Q

Sublimaze

A

Q72 hours

Must have been taking morphine 60 mg equivalent for at least 7 days

441
Q

Morphine conversions

A

Morphine IV: 10mg PO: 30

Dilaudid IV: 1.5mg PO: 7.5

442
Q

Relistor

A

Methylnaltrexone
Peripheral mu antagonist
Opioid induced constipation

443
Q

Movantik

A

Naloxegol
Peripheral mu antagonist
Opioid induces constipation

444
Q

Migraine natural products

A

Butterbur, feverfew, magnesium, riboflavin, caffeine

445
Q

Treximet

A

Naproxen + sumatriptan

446
Q

Onzetra xsail

A

Sumatriptan

447
Q

Evzio

A

Naloxone autoinjector

448
Q

Amrix

A

Cyclobenzaprine

449
Q

Fexmid

A

Cyclobenzaprine

450
Q

LA SGA

A 
Haldol decanoate: 4 weeks
Risperdal consta: 2 weeks
Invega sustenna: 4 weeks
Invega trinza: 3 months
Ability maintenna: 4 weeks
Aristada (ability) 4-8 weeks
451
Q

EPS

A

Don’t use: FGA, risperidone, paliperidone

Do use: quetiapine

452
Q

Szicho metabolic effect

A

High risk: clozapine, olanzapine, quetiapine

Medium: risperidone, paliperidone

Low risk: FGA, ability, ziprasisone, lurasidone, asenapine

453
Q

Qt prolongation szicho drugs

A

Thioridazine, haloperidol, ziprasidone

454
Q

Szicho cv risk

A

Risperidone

455
Q

Clozapine rules

A

ANC > 1500
Check weekly for 6 MONTHS, q2weeks for 6 months, then monthly
D/c if it drops below 1000

456
Q

Bipolar depression

A

Lithium, lamotrigine, symbyax, lurasidone

457
Q

Bipolar mania

A

Valproate, lithium, carbamazepine (equetro), can add antipsyches

458
Q

Bipolar pregnancy

A

Lamotrigine, lurasidone if bipolar depression

459
Q

AIMS scale

A

PD scale measure involuntary movements

460
Q

Sinemet

A

Brown/black urine, hemolysis, sexual urges, priapism. Separate from iron and protein. Need 70-100 mg/day

461
Q

Ropinerole

A

Requip
DA agonist
PD

462
Q

Mirapex

A

Prmipexole
DA agonist
PD

463
Q

Neupro

A 
Rotigotine
DA 
PD
Patch
ONCE daily!
464
Q

Uloric

A

Febuxistat
Xanthine oxidase inhibitor

Safer with renal impairment and less rash risk than allopurinol

Can cause acute gout attack like allopurinol

465
Q

Probenecid

A

Uricosuric agent
Increases renal excretion of gout
Block PCN excretion
Don’t use with crcl<50 or G6PD deficiency

466
Q

Zurampic

A

Lesinurad
Uricosuric agent
Give with allopurinol or febuxustat

467
Q

Krystexxa

A

Pegloticase
Converts uric acid to allantoin
Don’t give with xanthine oxidase inhibitor

468
Q

Lesinurad

A

Zurampic
Gout
Uricosuric

469
Q

Gout drug interaction

A

Xanthine oxidase inhibitor (allopurinol or febuxustat-uloric) with mercaptopurine or azathioprine

470
Q

Elitek

A

Rasburicase

Treats TLS

471
Q

H pylori tests

A

Urea breath test and fecal antigen test.

D/c PPI, bismuth, and ABX 2 weeks before test

472
Q

H pylori

A

Bismuth subsalicylate
Metronidazole
Tetracycline
PPI BID OR esomeprazole QD

Pylera includes first 3

473
Q

Prevpac

A

Second line
Amoxicillin, clarithromycin, lansoprazole

Watch for PCN allergy- give with metronidazole instead

474
Q

Amitiza

A

Lubipristone

Constipation

475
Q

Entered

A

Alvimopan
Peripherally acting mu antagonist
Post operative prevention of ileus

476
Q

Linzess

A

Linaclotide
Constipation
Guanylate cyclase c agonist

477
Q

Trulance

A

Plecanatide
Guanylate cyclase c agonist
Constipation

478
Q

Viberzi

A

Eluxadoline
Peripheral mu-agonist
Diarrhea
C4

479
Q

Colchicine

A

Don’t use with 3A4 or Pgp
Inhibitor
Renal elimination
Myelosuppression, myopathy, diarrhea, decreases B12, neuropathy
1.2 PO followed by 0.6 1 hour later. DNE 1.8 in 1 hour or 2.4/
Day

480
Q

Metamucil

A

Psyllium

Bulk forming laxative

481
Q

Fibercon

A

Calcium polycarbophil

Bulk forming laxative

482
Q

Citrucel

A

Methylcellulose

Bulk forming laxatives

483
Q

Benefiber

A

Wheat dextrin

Bulk forming laxatives

484
Q

Milk of magnesia

A

Magnesium hydroxide

Osmotic

485
Q

Miralax

A

Peg3350

Osmotic

486
Q

Glycerin

487
Q

Lactulose

488
Q

Senna

489
Q

Bisacodyl

A

Dulcolax

Stimulant

490
Q

Golytely

A

Peg solution for bowel prep

491
Q

Fleet enema, osmoprep

A

Sodium phosphates

Osmotic for bowel prep

492
Q

Superb bowel kit

A

Bowel prep

Sodium sulfate, potassium sulfate, magnesium sulfate

493
Q

Entocort

A

Budesonide for chrones

494
Q

Uceris

A

Budesonide for ulcerative colitis

495
Q

Asacol

A

Mesalamine
Ghost shell
Had phenylalanine

496
Q

Canasa

A

Mesalamine
Suppository
Distal UC

497
Q

Rowasa

A

Mesalamine enema

Distal UC

498
Q

Stelara

A

Ustekinumab
Chrones dx
Psoriasis

499
Q

Tysabri

A

Natalizumab

CD not UC

500
Q

Entyvio

A

Vedolizumab

CD and UC

501
Q

Other chrones drugs

A

Budesonide, mTX, cimzia

502
Q

Other ulcerative colitis drugs

A

Mesalamine, cyclosporine, tofacitinib (xeljanz)

503
Q

Valerian

A

Anxiety, sleep, depression

504
Q

Passionflower

505
Q

Kava

A

Anxiety

Liver toxic

506
Q

Chamomile

A

Anxiety, GI health, chamomile

507
Q

St. John’s wort

A

Anxiety, depression

Photo sensitivity, serotonergic
Lowers seizure threshold

508
Q

Omega 3

A

Adhd, dyslipidemia, heart health, HTN, inflammation

509
Q

L-lysine

A

Cold sores

510
Q

Echinacea

A

Cold and flu

511
Q

Zinc

A

Cold and flu

512
Q

Vit c

A

Cold and flu

513
Q

Ginkgo

A

Dementia/memory

514
Q

Vit E

A

Dementia/ memory

515
Q

SAMe

A

Depression, osteoarthritis

Serotonergic

516
Q

Alpha lipoid acid

517
Q

Cinnamon

518
Q

Chromium

519
Q

Red yeast rice

A

Dyslipidemia

520
Q

Garlic

A

Dyslipidemia, HTN

521
Q

Plant sterol

A

Dyslipidemia

522
Q

Fibers

A

Dyslipidemia, GI health

523
Q

Calcium

524
Q

Magnesium

A

Dyspepsia, migraine

525
Q

Bitter orange

A

Energy/weight loss

Potential cardiac toxicity

526
Q

Caffeine

A

Energy/weight loss

527
Q

Guarana

A

Energy/weight loss

528
Q

Green tea powder

A

Energy/weight loss

529
Q

Ginseng

530
Q

L-arginine

531
Q

Yohimbe

A

ED

Increases BP/HR, seizure risk

532
Q

CoenzymeQ10

A

Heart health, HTN

533
Q

Hawthorn

A

Heart health

Positive ionotrop- avoid with digoxin

534
Q

Flaxseed oil

A

Inflammation

535
Q

Turmeric

A

Inflammation , osteoarthritis

536
Q

Black cohosh

A

Menopause

May be hapatotoxic

537
Q

Evening primrose

538
Q

Soy

A

Menopause, osteoporosis

Phytoestrogens can increase risk of breast cancer

539
Q

Red clover

540
Q

Feverfew

541
Q

Butterbur

542
Q

Riboflavin

543
Q

Ginger

A

Motion sickness

544
Q

Peppermint

A

Motion sickness

545
Q

Glucosamine

A

Osteoarthritis

546
Q

Chondroitin

A

Osteoarthritis

547
Q

Saw palmetto

548
Q

Tea tree oil

549
Q

Herbals with bleeding risk

A

Garlic, ginkgo, ginseng, glucosamine, ginger, willow tree bark, fish oil, dong quai, vitamin E

550
Q

Michaelis mention drug

A

Theophylline, voriconazole, phenytoin

551
Q

Phenytoin adjustment

552
Q

Naranjo scale

A

Likelihood that drug caused the ADR

553
Q

Valerian

A

Anxiety, sleep, depression

554
Q

Passionflower

555
Q

Kava

A

Anxiety

Liver toxic

556
Q

Chamomile

A

Anxiety, GI health, chamomile

557
Q

St. John’s wort

A

Anxiety, depression

Photo sensitivity, serotonergic
Lowers seizure threshold

558
Q

Omega 3

A

Adhd, dyslipidemia, heart health, HTN, inflammation

559
Q

L-lysine

A

Cold sores

560
Q

Echinacea

A

Cold and flu

561
Q

Zinc

A

Cold and flu

562
Q

Vit c

A

Cold and flu

563
Q

Ginkgo

A

Dementia/memory

564
Q

Vit E

A

Dementia/ memory

565
Q

SAMe

A

Depression, osteoarthritis

Serotonergic

566
Q

Alpha lipoid acid

567
Q

Cinnamon

568
Q

Chromium

569
Q

Red yeast rice

A

Dyslipidemia

570
Q

Garlic

A

Dyslipidemia, HTN

571
Q

Plant sterol

A

Dyslipidemia

572
Q

Fibers

A

Dyslipidemia, GI health

573
Q

Calcium

574
Q

Magnesium

A

Dyspepsia, migraine

575
Q

Bitter orange

A

Energy/weight loss

Potential cardiac toxicity

576
Q

Caffeine

A

Energy/weight loss

577
Q

Guarana

A

Energy/weight loss

578
Q

Green tea powder

A

Energy/weight loss

579
Q

Ginseng

580
Q

L-arginine

581
Q

Yohimbe

A

ED

Increases BP/HR, seizure risk

582
Q

CoenzymeQ10

A

Heart health, HTN

583
Q

Hawthorn

A

Heart health

Positive ionotrop- avoid with digoxin

584
Q

Flaxseed oil

A

Inflammation

585
Q

Turmeric

A

Inflammation , osteoarthritis

586
Q

Black cohosh

A

Menopause

May be hapatotoxic

587
Q

Evening primrose

588
Q

Soy

A

Menopause, osteoporosis

Phytoestrogens can increase risk of breast cancer

589
Q

Red clover

590
Q

Feverfew

591
Q

Butterbur

592
Q

Riboflavin

593
Q

Ginger

A

Motion sickness

594
Q

Peppermint

A

Motion sickness

595
Q

Glucosamine

A

Osteoarthritis

596
Q

Chondroitin

A

Osteoarthritis

597
Q

Saw palmetto

598
Q

Tea tree oil

599
Q

Herbals with bleeding risk

A

Garlic, ginkgo, ginseng, glucosamine, ginger, willow tree bark, fish oil, dong quai, vitamin E

600
Q

Peanut/soy allergy drugs

A

Clevidipine, propofol, progesterone

601
Q

Egg allergy drugs

A

Clevidipine, propofol, yellow fever vaccine

Flublok is egg free

602
Q

Sulfa drugs

A

Thiazides Diuretics, loop diuretics (except ethacrynic acid), sulfonylureas, acetazolamide, Zonisamide, celecoxib, darunavir

Sulfites do not react

603
Q

Rumack-Mathew nomogram

A

APAP poisoning

If it falls above the line give NAC

604
Q

Cetylev

A

N-acetyl cycsteine

APAP OD

605
Q

Physistigmine

A

Acetylcholineesterase inhibitor

Cholinergic toxicity

606
Q

Beta blocker toxicity

607
Q

Calcium channel blocker OD

A

IV calcium

Or glucagon

608
Q

Methylene blue

A

Given for methhemoglobinemia

Avoid use is G6PD deficiency

609
Q

G6PD

A

RBC missing enzyme, hemolytic anemia

Favs beans, dapsone, methyleneblue, nitrofurantoin, pegloticase (krystexa), primaquin, rasburicase, sulfonamides

610
Q

RPR (rapid plasma reagin)

A

Syphilis test

611
Q

Carbamazepine level

A

4-12 mcg/mL

612
Q

Phenytoin level

A

10-20 mcg/mL

Of 1-2.5 mcg/mL free

613
Q

Theophylline level

A

5-15 mcg/mL

614
Q

Valproate level

A

50-100 mcg/mL

Can use phenytoin equation for low albumin

615
Q

Digoxin level

A
  1. 8-2 for afib

0. 5-0.9 for HF

616
Q

Gentamicin/tobramycin level

A

Peak 5-10

Trough <2

617
Q

Dimercaprol

A

Arsenic, gold, mercury toxicity

618
Q

Penicillamine

A

Copper toxicity

619
Q

Succimer

A

Lead toxicity

620
Q

Sulfonylureas toxicity

A

Octreotide (sandistatin)

621
Q

Organophosphate toxicity

Insecticides, nerve gases, sarin

A

Atropine and pralidoxime

622
Q

Salicylate toxicity

A

Sodium bicarbonate to alkalinize urine

623
Q

Sodium bicarbonate

A

Can shorten QTC

624
Q

Toxicity from alcohols including ethylene glycol (antifreeze), diethylene glycol, methanol

625
Q

Snakebite anti-venom

A

Crotalidae polyvalent immune FAB

CroFab

626
Q

Activated charcoal rules

A

Within 1 hour
1gram/kg
Do not use with hydrocarbons (petroleum, gas, paint thinner) or anything that increases aspiration risk

627
Q

Ribasphere

A

Ribavirin
RSV, HepC (combo)

Hemolytic anemia
Avoid pregnancy during and 6 months after use (partners too) two forms BC

628
Q

Corgard

A

Nadalol

Non selective

629
Q

Malaria mosquito

A

Anopheles

P falciparum is most fatal malaria species

630
Q

Ixiaro

A

Japanese encephalopathy vaccine

631
Q

Yellow fever vaccine

A 
YF-VAX
Complete 10 days before arrival
CI with egg allergy
Live
SubQ
632
Q

Infant simethicone

633
Q

Carbapenem coverage

A

ESBL, pseudomonas, anearobes

Do not cover: atypicals, VRE, MRSA, c. Did, stenotrophomonas

Ertapenem does not cover PEA

634
Q

Azactam

A

Aztreonam

Cover pseudomonas and gram negative but not Anaerobes and not gram positive

635
Q

Quinolones

A

Cipro and levo have pseudomonas coverage

MGL, levo/moxi IV: PO=1:1

No renal dose adjustment for moxi

636
Q

Daptomycin

A

Don’t use for pneumonia, myopathy, rhabdo, falsely increase PT/INR

637
Q

Linezolid

A

Don’t use with MAOI, myelosuppression, optic neuropathy, seratonin syndrome, hypoglycemia, decreased platelet

1:1 IV:PO

638
Q

Synercid

A

Quinipristin/dalfopristin

Arthralgias, infusion reaction, hyperbilirubinemia, D5W only, central line

639
Q

Tigecycline

A

Tygacil
Increase risk of death
It is yellow/orange
Do not use for blood stream infection

640
Q

Clindamycin

A

Anaerobes, do not use if flattened D

No renal adjustments

641
Q

Pseudomonas coverage

A

Zosyn, cefepime, ceftazadime, aztreonam, quinolones, aminoglycosides, carbapenems, polymyxins

642
Q

Anaerobes

A

Metronidazole, clindamycin, cefotetan, cefoxitin, carbapenems, beta lactam/betalactamase, tigecycline , moxifloxacin

643
Q

Atypicals

A

Azithromycin, claritrhomycin, doxycycline, minocycline, quinolones

644
Q

ABX no renal dose adjustment

A

Dicloxacillin, nafcillin, ceftriaxone, clindamycin, doxycycline, linezolid, moxifloxacin, metronidazole, azithromycin/erythromycin

645
Q

IV:PO 1:1

A

Clindamycin, linezolid, metronidazole, doxycycline/mino , levofloxacin, moxifloxacin, bactrim
Fluconazole/isavu/posa/vori

646
Q

Fibrates

A

Decrease TG, can increase LDL when TG high

Fenoglide and lipofen with food

647
Q

Niacin

A

Increase HDL

Gout, BP, flush, take a bedtime

648
Q

Fish oils

A

Decrease TG, can increase LDL (NOT VASCEPA)

Give when TG>500

649
Q

Lovaza

A

Omega 3 ethyl esters

650
Q

Bike acid sequestrants

A

Decrease LDL, increase HDL, can increase TG

Welchol: decrease BG

Never take dry

Constipation

651
Q

Pcsk9

A

Heterozygous familial hyperccholesterolemia

Note: the specialties (loperamide and mipomersen are for homozygous)

652
Q

Lovastatin timing

A

Lovastatin IR with evening meal

Altoprev at bedtime

653
Q

Renvela

A

Sevelamer cabobanate
HCL is renagel

Non calcium non aluminum phosphate binder not systemically absorbed

654
Q

Fosrenol

A

Lanthanum

Phosphate binder- aluminum and calcium free

655
Q

ACOG

656
Q

Immunocomprimised

A

Prednisone equivalent of 20 mg or 2 mg/kg per day for 14 days

657
Q

Ferrous sulfate dried

A

50 mg elemental

658
Q

Venofer

A

Iron sucrose

Parenteral

659
Q

Feraheme

A

Feeumoxytol
Parenteral
Anaphylaxis

660
Q

Iron dextran

A

Parenteral iron

Give test dose bc anaphylaxis

661
Q

Triferic

A

Iron for HD, add to bicarbonate

662
Q

Nasocobal

663
Q

HGb goal for epogen

A

Start <10, d/c at 11

664
Q

SCD blood transfusion goal Hgb

A

No more than 10

Risk of iron over load

665
Q

SCD infections

A

S. Pneumoniae, h. Influenza, n. Meningitidis

Give prophylactic PCN BID until 5 y/o, continue indefinitely if spleen is removed

666
Q

SCD vaccine

A

Hib, pcv13

Asplenia: also give meningococcal, meningococcal B, ppsv23

667
Q

Hydroxyurea

A 
For >\= 3 mid-severe episodes/year
Myelosuppression, fetal toxicity
No live vaccines
Contraception 
HD
Give folic acid
668
Q

Deferasirox

A

Iron chelation, less toxicity than deferoxamine

Oral

669
Q

Deferiprone

A

Iron chelator
Less toxicity than deferoxamine
Oral

670
Q

Bactrim strength

A

Ds: 800/160
Ss: 400/80

671
Q

Uridine triacetate

A

Vistogard

Antidote for 5FU or capecitabine

672
Q

Granix

A

Tbo filgrastim

Note: start CSF no sooner than 24 hours after chemo

673
Q

Rocephin

A

Ceftriaxone

674
Q

Baxdela

A

Delafloxacin

675
Q

Ethyol

A

Amifostine

Give with cisplatin for nephrotoxicity

676
Q

Type of CINV

A

Acute: within 24 hours (5HT3)
Delayed: >24 hours(Nk1RA, corticosteroid, palonosetron)
Anticipatory: BZD

677
Q

Akynzeo

A

Palonosetron + netupitant

678
Q

Warm compress

A

Vinca alkaloids and etoposide

679
Q

Intrathercal chemo

A

Cytarabine, mtx, hydrocortisone, thiotepa

Must be preservative free!

680
Q

Duavee

A 
Bazedoxifene/estrogens
Osteoporosis
Must have INTACT uterus
Treats vasomotor symptoms too 
Increases risk of breast cancer (evista/raloxifene prevents it)

Equine
Also increased risk ovarian and endometrial cancer

681
Q

Reclast

A

Zolendronate
IV, yearly

Ibandronate comes as IV too (90 days)
These are preferred if esophagitis is present

Other injections are SQ

682
Q

Estrace

A

Topical estrogen

683
Q

Estring

A

Topical estrogen

684
Q

Vagifem

A

Topical estrogen

685
Q

Alora

A

Estradiol patch

Twice weekly

686
Q

Climara

A

Estradiol

Patch once weekly

687
Q

Vivelle dot

A

Estradiol

Patch twice weekly

688
Q

Premarin

A

Conjugated equine estrogen

689
Q

Provera

A

Medroxyprogesterone

690
Q

Prometrium

A

Micronized progesterone

691
Q

Zebeta

A

Bisoprolol

692
Q

Type 1 error

A

False positive

693
Q

Type 2 error

A

False negative

694
Q

Specificity

A

True negative rate

695
Q

Sensitivity

A

True positive rate

696
Q

Standard deviation

A

1: 68%
2: 95%
3: 98%

697
Q

Power

A

Probability that a test will reject the null correctly. To avoid a type 2 error (false negative)

1-beta (beta is a type 2 error)

698
Q

Risk

A

Risk refer to bad outcome. So if there’s a ratio for a good outcome don’t use that. Example: 0.72 chance of good outcome: the risk is 0.28.

699
Q

Tests for continuous parametric (normal distribution) data

A

One-sample t test: date from one group is compared with gen pop
Paired/dependent t test : before and after date
Independent/unpaired/Student t test: two variables
Anova: three variables

700
Q

Discrete (categorical) data tests

A

Chi squared: nominal or ordinal (for one or two groups)
Fishers exact (for two groups)
Mann Whitney:
Kruskal Wallis: 3 or more groups
Wilcoxin signed rank: before and after data
**kruskal Wallis, man Whitney, wilcoxin signed rank can be used for non parametric data too (non normally distributed)

701
Q

Pharmacoeconomica

A

Identifies, measures, and compares the costs and consequences of pharmaceutical products and services

702
Q

ECHO model

A

Broad evaluative framework to assess outcomes associated with dx and treatments
Economic, clinical, humanistic
Direct, indirect, and intangible costs

703
Q

Cost minimization analysis

A

Both interventions are equivalent in outcomes and you are comparing the cost

704
Q

Cost benefit analysis

A

Comparing cost and benefit of an intervention in monetary units (dollars)

Difficult when looking at QOL

705
Q

Cost effectiveness analysis

A

Most common in literature

Cost is monetary but outcomes are clinical (LDL, cure rate, length of stay)

Hard to compare different programs like DM vs asthma (BG vs PFTs)

706
Q

Cost utility analysis

A

Form of CEA that uses QALYs and DALYs (disability adjust life years)
CEA can measure quantity of years but NOT quality aka utility
Takes into account quantity (mortality) and quality (morbidity)

707
Q

MSDS

A

Material safety data sheet

708
Q

Temperature monitoring frequency

A

Daily (minimally)

709
Q

Air pressure monitoring frequency

A

Each shift preferably, or daily minimally

710
Q

Glover fingertip test frequency

A

At initial training

Annually for low-medium risk

Semi-annually for high risk

711
Q

Air sampling frequency

A

Every 6 months

712
Q

Unpacking HD PPE

A

One pair chemo gloves (unlike 2 which is required for compounding,

Elastomeric half mask with multi gas cartridge and p100 filter

713
Q

Sodium hypochloride

A

Bleach- used to decontaminate surfaces that have been exposed to HD

714
Q

What can’t be done in closed system

A

Opening ampule

715
Q

Black bins

A

Bulk antineoplastic waste container

Unused or partially used iv bags, syringes, or vials

716
Q

Peroxide

A

Can deactivate and decontaminate

717
Q

Cleaning order

A

For a hood clean from cleanest to dirtiest but for the general rooms (buffer, ante, PeC) do from dirtiest to cleanest

718
Q

HD definition

A

Teratogenic, carcinogenic, genotoxic, reproductive toxicity, organ toxicity at low doses

719
Q

Yellow bins

A

Trace HD waste: empty vials and syringes

720
Q

Red bins

A

Sharps & non-hazardous waste

721
Q

When to give perioperative cefazolin

A

1 hour before incision

If quinolone or Vanco, start 120 mins before

722
Q

Syphillis

A

Bicillin LA NOT CR

Can use doxycycline

723
Q

COPD exacerbation ABX

A

Give it purulence, increased sputum, and dyspnea: if purulence, you only need two of 3

Augmentin

724
Q

CAP pathogens

A

Mycoplasma pneumonia, haemophilus influenza, strep pneumonia

725
Q

Prophylactic ABX duration

A

24 hours, cardiac surgery can be 48 hours

726
Q

Whooping cough

A

Azithromycin if caused by pertussis

ABX not indicated in uncomplicated bronchitis

727
Q

Latent tb treatment

A

Isoniazid for 9 months (preferred for HIV, pregnant, children)

Rifampin x 4 months

Isoniazid + rifapentine weekly for 12 weeks

728
Q

Active TB

A

RIPE x 2 months

RI x 4 months

729
Q

Endocarditis organisms

A

Staph, strep, enterpcocci

730
Q

Comminution

A

Reduce particle size by grinding, crushing, milling, vibrating ext

Trituration, levigation (with levigating or wetting agent…use mineral oil for lipid or glycerin for aqueous

731
Q

Trituration

A

Mix thoroughly or make homogenous

Grinding tablets or shaking emulsion

732
Q

Levigating

A

Trituration of powder with mortar and pestle

733
Q

Spatulation

A

Levigation but on an ointment slab with a spatula

734
Q

Pulverization by intervention

A

Crystals dissolved, then recystalize and are finer at that point

735
Q

Compounding: assigning an expiration to an ingredient that doesn’t have one

A

No more than 3 years

736
Q

Continental

A

Dry gum
OWE: 4:2:1
Gum (emulsifier) levigated with oil then water added all at once. Then triturate by shaking. Then add other ingredients. Then QS with water. Then homogenize

737
Q

English

A

Wet gum
OWE: 4:2:1
Triturate gum and water to form mucilage. Then add oil slowly while triturating. Add other ingredients. QS with water. Homogenize.

738
Q

Magnesium stearate

A

Improves flow ability of power

Glidant/lubricant

739
Q

Sodium lauryl sulfate

A

Surfactant

Neutralize static charge to keep powder from floating away

740
Q

Compounding: magnesium oxide

A

Adsorbent powder, keeps powder dry

741
Q

Compounding: magnesium carbonate

A

Adsorbent powder, keeps powder dry

742
Q

Kaolin

A

Adsorbent powder, keeps powder dry

743
Q

Hypromellose

A

Vegetable product. Use for compounding if can’t use gelatin

744
Q

Oil soluble suppository base

A

Cocoa butter aka theobroma oil

745
Q

Water soluble suppository base

A

PEG, gelatin

746
Q

Non sterile compounding BUD

A

Non aqueous: 6mo(180 days)- room temperature

Aqueous oral: 14 days in fridge

Aqueous topical: 30 days- room temp

747
Q

Pyrogens

A

Endotoxins that can come from g+ of g-. Tap water. Should clean equipment in dry heat sterilization (autoclave).
Reagent first bacterial endotoxin test is limilus amebocyte lysate

748
Q

HAM D

A

Depression assessment scale

Aka HDRS

749
Q

Depression augmentation drugs

A

Buspirone, low dose atypical antipsychotic, ability, symbyax, quetiapine ER, brexiprazole (rexulti), esketamine, maybe lithium

750
Q

Pregnancy depression

A

Don’t use paroxatine: cardiac effects

SSRIs can cause persistent pulmonary hypertension of newborn

Breastfeeding: use SSRI or tricyclic but not doxepin

751
Q

Premenstrual dysphoric disorder

A

Fluoxetine (Sarafem), sertraline

Taken QD for two weeks prior

752
Q

MAO washout

A

2 weeks for Any AD, but 5 weeks for fluoxetine to MAOI

Still 2 week for MAOI to fluoxetine

753
Q

Bupropion max dose

A

450mg/day d/t seizure risk

754
Q

Emsam

A

Selegiline patch for depression. Change once daily

Zelapar is ODT for PD

755
Q

Rytary

A

Carbodopa levodopa ER capsule

756
Q

MMSE

A

Mini mental state examination

Alzheimer’s

Score less than 24 indicates memory d/o

757
Q

Patches to remove for MRI

A

Scopolamine, testosterone, estogens, diclofenac, rotigotine (neupro), clonidone

758
Q

Exelon

A

Rivastigmine patch
Acetylcholine esterase inhibitor

Alzheimer’s

Daily patch
Upper or lower back, upper arm or chest

759
Q

Razadyne

A

Galantamine

Acetylcholine esterase inhibitor

Alzheimer’s

760
Q

Alzheimer’s less nauseating meds

A

Take donepezil QHS

Exelon patch, donepezil ODT

761
Q

Acetylcholine esterase inhibitor warning

A

Bradycardia

Also causes significant nausea and can cause insomnia

762
Q

Status epilepticus

A

5-20 mins give BZD

20-40 mins give fosphenytoin, valproate, levetiracetam, phenobarbital

763
Q

BZD Moa

A

Increase GABA

764
Q

Valproate moa

A

Increase GABA

765
Q

Ethisuximide moa

A

T type calcium channel blocker

766
Q

Carbamazepine moa

A

Sodium channel blocker

767
Q

Phenytoin moa

A

Sodium Channel blocker

768
Q

Topiramate ADRs

A

Metabolic acidosis. Watch bicarbonate. Increases IOP, fetal harm, nephrolithiasis, hyperammonemia, oligohidrosis

769
Q

Valproate ADR

A

Hyperammonemia, alopecia (just like lamotrigine-give zinc/selenium) note: phenytoin causes hair growth
Watch platelets and lfts
Hepatic failure, pancreatitis, and fetal harm are boxed warnings

This drug can also be used for migraine prophylaxis

770
Q

Carbamazepine adrs

A

Myelosuppression, Aplastic anemia, agranulocytosis, skin reaction, hyponatremia
Check CBC and platelets
Autoinducer

771
Q

Felbamate adr

A

Hepatic failure, aplastic anemia

772
Q

Zonisamide adrs

A

Sulfa allergy, oligohidrosis/hyperthermia, nephrolithiasis

More Drugs (4 decks)

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