Naomi non medical prescribing Revision Flashcards
What is pharmacokinetics?
What the body does to the durg
What is pharmacodynamics?
What the drug does to the body.
What is ADME mean?
Absorption, Distribution, metabolism, excretion
Half life is….
the time required to reduce plasma concentration of drug to half its original value.
What is a therapeutic index?
A ratio that compares the blood concentration at which a drug becomes toxic and the concentration at which the drug is effective
What are the four areas of law to consider?
P- professional, I- Individual (civil law), E- Employer ( employment law and liability), S- Society ( criminal law)
Describe an agonist.
An agonist is a chemical that binds to a receptor and elicits an appropriate physiological response
What is an Antagonist?
An Antagonist is a drug that bind to a receptor and whose presence prevents a physiological response or other drugs from binding. Antagonists Block receptor activation by agonists.
What is the first pass metabolism?
drug metabolism whereby the concentration of a drug is greatly reduced by the liver before it reaches the systemic circulation.
It is the fraction of drug lost during the process of absorption which is generally related to the liver and gut wall.
what is high hepatic ratio?
if a drug has a high hepatic ratio, drug clearance is highly affected by hepatic blood flow.
What is low hepatic ratio?
if a drug has a low hepatic ratio, drug clearance is independent of hepatic blood flow, but depends on metabolic capacity of the liver.
What does an off label mean?
Off label means the medication is being used in a manner outside the marketing authorisation
what is polypharmacy?
Concurrent use of multiple medication items by one person.
describe an enzyme inhibitor.
A substance that blocks the action of an enzyme
What does EASE stand for?
E- Effective
A- appropriate
S-safe
E- cost effective.
name the 5 rights in prescribing
M-Medication
D-Dose
T-Timing
R- Route
P- Patient
Define pharmacology
The study of properties of drugs and their interaction on living organisms and viruses.
Define bioavailability.
This is the percentage of a dose entering the systemic circulation after administration of a given dose form.
Define Efficacy
Capacity of a drug to prodcue an alteration in a target cell/organ after binding to its receptor.
its the maximum effect the drug will produce, irregardless of the dose
What does Steady State mean?
Steady-state concentration occurs when the amount of a drug being absorbed is the same amount that’s being cleared from the body when the drug is given continuously or repeatedly. Steady-state concentration is the time during which the concentration of the drug in the body stays consistent
What is a partial agonist?
A partial agonist cannot produce the maximum response acting on receptors.
How do you report an adverse Drug Reaction?
yellow Card
What is an adverse Drug Reaction?
When a side effect occurs above the usual/expected level, it becomes an adverse drug reaction.
What is a full agonist?
Can produce the maximum response on receptors.
