Nagel review Flashcards

1
Q

Types of native extracts:

A
Complex fractions
* fresh extracts
* liquid extracts of dry plants
* solid extracts
Simplified fractions (standardized to a ratio) 
Isolated constituents (drug salts, Rx)
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2
Q

Examples of a fresh extract?

A

juice (fresh, bottled, freeze-dried)
green tincture
mother tincture

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3
Q

Examples of a liquid extract?

A
decoction
infusion
hydroalcoholic (tincture - 1:2 to 1:10)
spagyric
fluid extract 1:1
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4
Q

Characteristics of a solid extract?

A

standardized and concentrated
original solvent removed
2:1 or higher

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5
Q

According to Dr. Brinker, herbs processed the least have the (most/least) side effects and are the (most/least) complex.

A

least side effects
most complex

thus, more process => more side effects, less complex

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6
Q

In the Hollywood method, which herbal player corresponds to the Director?

A

Activator or harmonizer

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7
Q

In the Hollywood method, which herbal player corresponds to the Lead actor? Supporting actor?

A

lead - primary medicinal herb

supporting - supporting herb (also behind the scenes)

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8
Q

In the Hollywood method, which herbal player corresponds to the screenwriter? Producer?

A

screenwriter - overall concept

producer - form of herbal product

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9
Q

What factors might play a role in tincture incompatibility?

A
solubility
miscibility
polarity
pH
precipitation
temperature
solvent used
solvent %
botanical matrix
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10
Q

T/F: Alkaloids are more soluble at alkaline pH.

A

false

soluble at acid pH
precipitate in alkaline, tannic, or salicylates

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11
Q
Arrange in order of polarity (least to most)
glycerine
fixed oils
ethanol
water
A

fixed oils -> ethanol -> glycerine -> water

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12
Q

Tinctures are made using the (weight/volume) of herb and the (weight/volume) of menstruum.

A

weight of herb

volume of menstruum

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13
Q

Menstruum % for variable solubilities of constituents:

A
  • 85-95%: resins, EOs
  • 75-95%: alkaloids
  • 60-85%: glycosides, tannins
  • 45%: when in doubt
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14
Q

Maceration:

A

to soak, fresh or dried, more common; slow

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15
Q

Percolation:

A

slow passing thru powdered herb; fast

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16
Q

Alcohol - advantages and disadvantages:

A

A: natural source, min 25% to preserve, best preservative and sanitizer, best solvent for 2nd plant constituents, Peripheral circulatory action, minimal processing, readily absorbed, convenient and versatile

D: taste, high glycemic index, safety (kids, alcoholics, etc), Compliance issues, cost issues

17
Q

Glycerine - advantages and disadvantages:

A

A: fair solvent, good preservative, low glycemic index, sweet taste

D: unnatural/fat saponification; need 65% to stabilize; diarrhea in 1-2 oz

18
Q

United Plant Savers considers these herbs “at risk”.

A

o American Ginseng - Panax quinquefolius
o Black Cohosh - Actaea racemosa (Cimicifuga)
o Bloodroot - Sanguinaria canadensis
o Blue Cohosh - Caulophyllum thalictroides
o Echinacea - Echinacea spp.
o Eyebright - Euphrasia spp.
o False Unicorn Root - Chamaelirium luteum
o Goldenseal - Hydrastis canadensis
o Lady’s Slipper Orchid - Cypripedium spp.
o Lomatium - Lomatium dissectum (debatable)
o Osha - Ligusticum porteri, L. spp.
o Peyote - Lophophora williamsii
o Slippery Elm - Ulmus rubra
o Sundew - Drosera spp.
o Trillium, Beth Root -Trillium spp.
o True Unicorn - Aletris farinosa
o Venus’ Fly Trap - Dionaea muscipula
o Virginia Snakeroot - Aristolochia serpentaria
o Wild Yam - Dioscorea villosa, D. spp.

19
Q

Effects of hepatic fructose metabolism:

A

HTN
lipogenesis
dyslipidemia
hepatic steatosis

20
Q

Cardiotonic herbs are:

A

herbs that have a beneficial action on the heart and blood vessels but do not contain cardiac glycosides.

21
Q

Cardiotonic herbs:

A

Crataegus
Tilia
Allium sativum
Leonurus

22
Q

A circulatory stimulant is:

A

a substance that improves blood flow through body tissues and is generally warming.

23
Q

Circulatory stimulating herbs:

A

Capsicum
Rosmarinus
Zingiber

24
Q

A peripheral vasodilator is:

A

A substance that dilates or widens peripheral blood vessels and improves circulation.

25
Peripheral vasodilating herbs:
Crataegus Tilia Ginkgo
26
A hypotensive is:
a substance that reduces blood pressure
27
Hypotensive herbs:
Crataegus Rauwolfia Coleus Viscum (mistletoe family)
28
Commonly used herbs for lipid disorders:
``` allium sativum allium cepa commiphora mukul cynara scolymus trigonella monascus purpureus (red yeast rice) glycine max (soybean) ```
29
What herb works like a statin?
monascus purpureus
30
What herbs might is contraindicated in pts on blood thinners?
trigonella (fenugreek) - contains coumarins
31
Commonly used herbs for hypertension:
``` cardiotonics: * crataegus * tilia * ginkgo * allium sativum * ocimum sanctum * olive leaf * melissa * leonurus * beta vulgaris root low dose: * rauwolfia * veratrum viride * gelsemium * viscum album ```
32
Herbal diuretics:
``` apium graviolens (celery - 7 stalks/day) petroselinum (parsley) taraxacum urtica dioica solidago uva-ursi equisetum galium aparine (cleavers) juniperus ```
33
What actions make beets (beta vulgaris) useful in HTN?
* powerful nitric oxide stimulator: acute hypotensive, vasoprotective, anti-platelet * bioconversion (lingual bacteria) nitrate → nitrite * useful in degen heart dz
34
The genius of Crataegus:
o opens doorway btw heart and spirit (to underworld) o frounding, opening o loss of vision, stuck in a mundane world o profound strength o openness and giving o doorway to light from darkness o balance of opposites o compassion, strength, flexibility and stuckness
35
What's the dosing of Rauwolfia?
* Whole root: 2 mg QD - BID * Reserpine: 0.1 - 0.3 mg BID - TID * Tincture: 0.1 mg reserpine per 4 - 8 gtts BID
36
Describe the toxicity and indications of Rauwolfia:
* Toxicity: best hypotensive with fewest side effects * Sm-med doses: diarrhea, nasal congestion, drowsy, bradycardia * Lg doses: for psychosis → PD tremor sxs (reversible) * Avoid CNS depressants, anti-epileptics * Possible correlation with Breast Cancer * Drug interactions: digitoxin, beta-blockers, levodopa * Reserpine CI: hypersensitivity, depression, PUD, UC, electroconvulsive tx
37
Compare European, Western, and Drop (homeopathic) dosing:
European: focus on pharmacological amt of constituent, lg amt - 5mL TID. Western: Moderate amt of medicine - 30-60 gtts. Drop (homeopathic): focus on energetic match, small amt of medicine, 1-5 gtts.
38
Naturopathic concerns with using toxic botanicals:
Liability of prescribing toxics **dosing and potency of the product - Drops of water (minim) vs tincture Highest quality is important; choose suppliers carefully Ask for assayed levels of constituents (vs standardized) potential interactions with compounding Don’t make yourself! Consider homeopathic or Rx as alternative