MYSASTHENIA GRAVIS Flashcards

1
Q

Which drugs are given to patients with Myasthenia gravis?

A
  1. Acetylcholinesterase
    - Neostigmine
    - Pyridostigmine (slower in action)
  2. Immunosuppressants
    - Azathioprine
  3. Corticosteroids
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1
Q

What are the side effects of
Acitcholinesterases?

A

Muscarinic side-effects:
1. Increased sweating
2. Increased salivary
3. Gastric secretions
4. Increased Gl and uterine motility
5. Bradycardia

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2
Q

Which drug can be used to antagonise the acetylcholinesterase effects?

A

Atropine

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3
Q

Which drugs should you avoid in
Myasthenia Gravis?

A
  1. Antibiotics
    - Aminoglycosides
    - Macrolides
    - Quinolones
    - Tetracyclines
  2. Anti-Malarials
    - Chloroquine
    - Quinine
  3. Beta-Blockers
  4. Anti-psychotics
  5. Lithium
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