Myopathy And Muscle Pain Syndrome Flashcards
A group of muscle disease
Myopathy
Most common primary symptom of myopathy
Proximal limb muscle weakness
Muscular Dystrophies
BLEDFC
Becker’s Limb girdle Emery dreifuss Duchenne Fascioscapulohumeral Congenital
Congenital myopathy
CCMN
Central core myopathy
Congenital fiber disproportion myotubular myopathy
Nemaline myopathy
Metabolic myopathies
PAMD
Phophofructokinase
Acid maltase deficiency
Muscle phosphorylase def
Debranching enzyme deficiency
Endocrine myopathies
HHHHC
Hyperthyroidism
hypothyroid myopathy hyperparathyroidism hypothyroidism
corticosteroid myopathy
Inflammatory myopathies PDS
Polymyositis
dermatomyositis
sarcoidosis
Toxic myopathies
Alcohol myopathy
medications
Infectious myopathies
Cysticercosis
HIV
trichinosis
Four obligatory criteria for muscular dystrophy
- Primary myopathy
- Genetic basis for the disorder
- Course that is progressive
- Degenration and death of muscle fibers occur at some stage in the disease.
Basic symptoms of muscular dystrophy
Muscle weakness muscle deformities contracture deformities scoliosis enlargement of the calve muscles
Focal atrophy of distal lower extremity muscles
Stork leg appearance
Particularly seen in hereditary motor sensory neuropathy
Characterized by difficulty arising from floor
four point stance on hands and knees
Gower’s sign
Weakness of the hip extensors produces anterior pelvic tilt and tendency for trunk to be positioned anteriorly to the hip
Toe walking or myopathic gait
Weakness of hip abductors produces tendency toward lateral pelvic tilt and pelvic drop of swing face side
Trendelenburg gait/ gluteus medius gait
Commonly seen in stroke patients and it facilitates clearance of plantar flexed ankle
Steppage gait/ foot slap
X-linked disorder
Xp21 gene loci
Deficiency of dystrophin which disrupts the cytoskeleton
Duchenne muscular dystrophy
Positive sharp waves/PSW, positive fibrillation potential
rain drops on a roof and crumbling a plastic
Duchenne muscular dystrophy