Myopathy And Muscle Pain Syndrome

Question 1

A group of muscle disease

Answer 1

Myopathy

Question 2

Most common primary symptom of myopathy

Answer 2

Proximal limb muscle weakness

Question 3

Muscular Dystrophies

BLEDFC

Answer 3

Becker’s
Limb girdle
Emery dreifuss
Duchenne
Fascioscapulohumeral
Congenital

Question 4

Congenital myopathy

CCMN

Answer 4

Central core myopathy
Congenital fiber disproportion myotubular myopathy
Nemaline myopathy

Question 5

Metabolic myopathies

PAMD

Answer 5

Phophofructokinase
Acid maltase deficiency
Muscle phosphorylase def
Debranching enzyme deficiency

Question 6

Endocrine myopathies

HHHHC

Answer 6

Hyperthyroidism
hypothyroid myopathy hyperparathyroidism hypothyroidism
corticosteroid myopathy

Question 7

Inflammatory myopathies PDS

Answer 7

Polymyositis
dermatomyositis
sarcoidosis

Question 8

Toxic myopathies

Answer 8

Alcohol myopathy

medications

Question 9

Infectious myopathies

Answer 9

Cysticercosis
HIV
trichinosis

Question 10

Four obligatory criteria for muscular dystrophy

Answer 10

1. Primary myopathy
2. Genetic basis for the disorder
3. Course that is progressive
4. Degenration and death of muscle fibers occur at some stage in the disease.

Question 11

Basic symptoms of muscular dystrophy

Answer 11

Muscle weakness 
muscle deformities 
contracture deformities 
scoliosis 
enlargement of the calve  muscles

Question 12

Focal atrophy of distal lower extremity muscles

Answer 12

Stork leg appearance

Particularly seen in hereditary motor sensory neuropathy

Question 13

Characterized by difficulty arising from floor

four point stance on hands and knees

Answer 13

Gower’s sign

Question 14

Weakness of the hip extensors produces anterior pelvic tilt and tendency for trunk to be positioned anteriorly to the hip

Answer 14

Toe walking or myopathic gait

Question 15

Weakness of hip abductors produces tendency toward lateral pelvic tilt and pelvic drop of swing face side

Answer 15

Trendelenburg gait/ gluteus medius gait

Question 16

Commonly seen in stroke patients and it facilitates clearance of plantar flexed ankle

Answer 16

Steppage gait/ foot slap

Question 17

X-linked disorder
Xp21 gene loci
Deficiency of dystrophin which disrupts the cytoskeleton

Answer 17

Duchenne muscular dystrophy

Question 18

Positive sharp waves/PSW, positive fibrillation potential

rain drops on a roof and crumbling a plastic

Answer 18

Duchenne muscular dystrophy

Question 19

Markedly elevated in the duchenne muscular dystrophy

Answer 19

Creatinine kinase MM

Question 20

Malignant hyperthermia during general anesthesia with favor of greater than 40°C

Answer 20

Duchenne

Question 21

Positive posterior axillary depression sign

Answer 21

Duchenne

Question 22

Duchenne

Knows of ambulation usually by age ____

Answer 22

10(7-13)

Question 23

Is present both in myocardium and cardiac purkinje fibers

Answer 23

Dystrophin

Question 24

Respiratory assistance is initiated when vital capacity decreases to approximately ____

Answer 24

20%

Question 25

Consider need to increase respiratory assistance /Mechanical ventilator when vital capacity fails to_____ of predicted

Answer 25

10%

Question 26

Physiatric management of Duchenne muscular dystrophy

Answer 26

Control of contractures and maintain mobility by ambulation electrical stimulation hand function

Question 27

Duchenne muscular dystrophy functional detoriation of the arms begins around age

Answer 27

10 and plateauing 2 1/2 years

Question 28

X-linked inheritance but with later and slower rate of progression Xp21 Abnormal or insufficient dystrophin

Answer 28

Becker muscular dystrophy

Question 29

Abnormal gait lordotic posture functional disability with hopping and rising from floor sound is like a starting motorcycle engine in myopathic potential

Answer 29

Limb girdle muscular dystrophy

Question 30

A slowly progressive dystrophic myopathy with predominant involvement of facial and shoulder girdle musculature with linkage to chromosome 4q35

Answer 30

Fasciscapulohumeral muscular dystrophy

Question 31

Positive sardonic grin | change in muscle biopsy shows isolated small atrophic fibers

Answer 31

Fascioscapulohumeral muscular dystrophy

Question 32

Myotonic muscular dystrophy is AKA

Answer 32

Steinert disease

Question 33

Myotonic muscular dystrophy defect in chromosome

Answer 33

19 at 19q13 | ‼️Causes dysfunction in multiple organ system

Question 34

Clinical manifestations : | facial wasting and hypotonia in infancy high arched palate

Answer 34

Myotonic muscular dystrophy

Question 35

Arrhythmias and mitral valve prolapse are increased

Answer 35

Myotonic muscular dystrophy

Question 36

A popular diagnostic label for centuries old disorder of fatigue and multiple somatic complaints

Answer 36

Chronic fatigue syndrome

Question 37

Major clinical component of myofascial pain syndrome | give three

Answer 37

Trigger point, taut band, local twitch response

Question 38

Repent city to cause pain at a distance site, usually the belly of affected muscle

Answer 38

Trigger point

Question 39

A shortened group of muscle fibers and can best be palpated by sliding the skin and subcutaneous tissue perpendicularly across the fibers of the muscles

Answer 39

Taut band

Question 40

Snapping palpation of the taut and containing the trigger point Will produce a transient contraction of the band’s muscle fiber

Answer 40

Local twitch response

Question 41

Fibromyalgia AKA

Answer 41

Primary fibromyalgia syndrome

Question 42

History of widespread pain and pain in 11 of 18 tender points on distal palpation

Answer 42

Fibromyalgia

Question 43

Mainstay treatment for fibromyalgia

Answer 43

Spray and stretch

Question 44

Digitally applying pressure on Trigger point For one minute and gradually increasing pressure as tolerated up to 30 pounds

Answer 44

Ischemic compression technique

Question 45

This is following unaccustomed exercise and using untrained muscles and picks 24 to 48 hours after exercise

Answer 45

Post exercise muscle soreness