Myopathy And Muscle Pain Syndrome Flashcards

1
Q

A group of muscle disease

A

Myopathy

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2
Q

Most common primary symptom of myopathy

A

Proximal limb muscle weakness

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3
Q

Muscular Dystrophies

BLEDFC

A
Becker’s
Limb girdle
Emery dreifuss
Duchenne
Fascioscapulohumeral
Congenital
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4
Q

Congenital myopathy

CCMN

A

Central core myopathy
Congenital fiber disproportion myotubular myopathy
Nemaline myopathy

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5
Q

Metabolic myopathies

PAMD

A

Phophofructokinase
Acid maltase deficiency
Muscle phosphorylase def
Debranching enzyme deficiency

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6
Q

Endocrine myopathies

HHHHC

A

Hyperthyroidism
hypothyroid myopathy hyperparathyroidism hypothyroidism
corticosteroid myopathy

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7
Q

Inflammatory myopathies PDS

A

Polymyositis
dermatomyositis
sarcoidosis

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8
Q

Toxic myopathies

A

Alcohol myopathy

medications

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9
Q

Infectious myopathies

A

Cysticercosis
HIV
trichinosis

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10
Q

Four obligatory criteria for muscular dystrophy

A
  1. Primary myopathy
  2. Genetic basis for the disorder
  3. Course that is progressive
  4. Degenration and death of muscle fibers occur at some stage in the disease.
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11
Q

Basic symptoms of muscular dystrophy

A
Muscle weakness 
muscle deformities 
contracture deformities 
scoliosis 
enlargement of the calve  muscles
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12
Q

Focal atrophy of distal lower extremity muscles

A

Stork leg appearance

Particularly seen in hereditary motor sensory neuropathy

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13
Q

Characterized by difficulty arising from floor

four point stance on hands and knees

A

Gower’s sign

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14
Q

Weakness of the hip extensors produces anterior pelvic tilt and tendency for trunk to be positioned anteriorly to the hip

A

Toe walking or myopathic gait

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15
Q

Weakness of hip abductors produces tendency toward lateral pelvic tilt and pelvic drop of swing face side

A

Trendelenburg gait/ gluteus medius gait

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16
Q

Commonly seen in stroke patients and it facilitates clearance of plantar flexed ankle

A

Steppage gait/ foot slap

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17
Q

X-linked disorder
Xp21 gene loci
Deficiency of dystrophin which disrupts the cytoskeleton

A

Duchenne muscular dystrophy

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18
Q

Positive sharp waves/PSW, positive fibrillation potential

rain drops on a roof and crumbling a plastic

A

Duchenne muscular dystrophy

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19
Q

Markedly elevated in the duchenne muscular dystrophy

A

Creatinine kinase MM

20
Q

Malignant hyperthermia during general anesthesia with favor of greater than 40°C

A

Duchenne

21
Q

Positive posterior axillary depression sign

A

Duchenne

22
Q

Duchenne

Knows of ambulation usually by age ____

A

10(7-13)

23
Q

Is present both in myocardium and cardiac purkinje fibers

A

Dystrophin

24
Q

Respiratory assistance is initiated when vital capacity decreases to approximately ____

A

20%

25
Q

Consider need to increase respiratory assistance /Mechanical ventilator when vital capacity fails to_____ of predicted

A

10%

26
Q

Physiatric management of Duchenne muscular dystrophy

A

Control of contractures and maintain mobility by ambulation electrical stimulation
hand function

27
Q

Duchenne muscular dystrophy functional detoriation of the arms begins around age

A

10 and plateauing 2 1/2 years

28
Q

X-linked inheritance but with later and slower rate of progression
Xp21
Abnormal or insufficient dystrophin

A

Becker muscular dystrophy

29
Q

Abnormal gait lordotic posture
functional disability with hopping and rising from floor
sound is like a starting motorcycle engine in myopathic potential

A

Limb girdle muscular dystrophy

30
Q

A slowly progressive dystrophic myopathy with predominant involvement of facial and shoulder girdle musculature with linkage to chromosome 4q35

A

Fasciscapulohumeral muscular dystrophy

31
Q

Positive sardonic grin

change in muscle biopsy shows isolated small atrophic fibers

A

Fascioscapulohumeral muscular dystrophy

32
Q

Myotonic muscular dystrophy is AKA

A

Steinert disease

33
Q

Myotonic muscular dystrophy defect in chromosome

A

19 at 19q13

‼️Causes dysfunction in multiple organ system

34
Q

Clinical manifestations :

facial wasting and hypotonia in infancy high arched palate

A

Myotonic muscular dystrophy

35
Q

Arrhythmias and mitral valve prolapse are increased

A

Myotonic muscular dystrophy

36
Q

A popular diagnostic label for centuries old disorder of fatigue and multiple somatic complaints

A

Chronic fatigue syndrome

37
Q

Major clinical component of myofascial pain syndrome

give three

A

Trigger point, taut band, local twitch response

38
Q

Repent city to cause pain at a distance site, usually the belly of affected muscle

A

Trigger point

39
Q

A shortened group of muscle fibers and can best be palpated by sliding the skin and subcutaneous tissue perpendicularly across the fibers of the muscles

A

Taut band

40
Q

Snapping palpation of the taut and containing the trigger point Will produce a transient contraction of the band’s muscle fiber

A

Local twitch response

41
Q

Fibromyalgia AKA

A

Primary fibromyalgia syndrome

42
Q

History of widespread pain and pain in 11 of 18 tender points on distal palpation

A

Fibromyalgia

43
Q

Mainstay treatment for fibromyalgia

A

Spray and stretch

44
Q

Digitally applying pressure on Trigger point For one minute and gradually increasing pressure as tolerated up to 30 pounds

A

Ischemic compression technique

45
Q

This is following unaccustomed exercise and using untrained muscles and picks 24 to 48 hours after exercise

A

Post exercise muscle soreness