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NCM 118 LEC > Myocardial Infarction > Flashcards

Myocardial Infarction Flashcards

1
Q

Irreversible MI damage happens when

A

20-40 minutes of MI

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2
Q

MI usually affects what chamber of the heart

A

Left ventricle

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3
Q

Causes of MI

A
  1. Atherosclerosis
  2. Vasospasm
  3. Decreased O2 supply
  4. Increased O2 demand
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4
Q

Ischemia meaning

A

Insufficient tissue oxygenation

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5
Q

Premature cell death

A

Necrosis

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6
Q

Blank cells/min if is blocked for blank

A

500 cells/min

>45 minutes

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7
Q

Death of tissues due to O2 deprivation

A

Infarction

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8
Q

What layer of the heart does infarction start

A

endocardial layer

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9
Q

Transmural Infarction

A

Necrosis extends through all layers of the myocardium

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10
Q

Small Damage transmural infarction

A

Dyskinetic - cannot contract in a coordinated manner

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11
Q

Extensive damage

A

Akinetic - unable to contract

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12
Q

Predisposing/Precipitating factors of MI

A 
Stress
Obesity
DM and HTN
Diet
African American
Age
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13
Q

Lab tests

A

Creatinine Kinase (CK-MB)
Myoglobin
Troponin

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14
Q

Heme protein that helps transport O2

A

myoglobin

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15
Q

Protein found in the myocardium; regulates myocardial contractile process

A

Troponin

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16
Q

3 isomers of Troponin

A

C, I, T

I, T - reliable and critical markers of myocardial injury

17
Q

Immediate treatment for MI

A

MONA TASS

18
Q

Medical Mgt Goals

A
  1. minimize myocardial damage
  2. preserve myocardial function
  3. prevent complications
19
Q

ACE inhibitors function

A

Prevents conversion of angiotensin I to angiotensin II which is a potent vasoconstrictot

20
Q

Thrombolytics function

A
  • administered 3-6 hours
  • initiated within 30 minute (door-to-needle time)
  • dissolve thrombus
  • allows reperfusion
21
Q

Emergent Percutaneous Coronary Intervention

A

Cardiac catherization - procedure to open the occluded artery

22
Q

How long should cardiac catheterization be performed

A

<60 minutes (door-to balloon time)

NCM 118 LEC (2 decks)

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