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PLE Microbiology > Mycology by Kurt Asperas > Flashcards

Mycology by Kurt Asperas Flashcards

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Biology 101 flashcards
1
Q

MOA of azole antifungals

A

inhibit ergosterol synthesis

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2
Q

allergiv bronchopulmonary aspergillosis

A

Aspergillus fumigatus

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3
Q

Aflatoxin causing liver cancer

A

Aspergillus flavus

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4
Q

Liver necrosis due to amanitin and phlloidin

A

Amanita mushrooms

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5
Q

Nonspecific agar for fungi

A

Saboraud’s agar (low pH inhibits bacteria)

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6
Q

Ringworms =

A

Dermatophytes

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7
Q

3 important dermatophytes

A

derMETophytes - Microsporum canis, Epidermophyton floccosum, Trichophyton tonsurans)

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8
Q

Green fluorescence on wood’s lamp

A

Ringworms (specifically microsporum)

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9
Q

Spaghetti and meatballs

A

Malassezia furfur (Tinea versicolor/An-an)

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10
Q

Rose gardeners

A

Sporothrix schenckii

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11
Q

DOC for Sporotrichosis

A

Itraconzole or Potassium Iodide

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12
Q

Mold in soil; SPHERULE in tissue

A

Coccidiodes immitis

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13
Q

Transmission of Coccidiodes immitis

A

inhalation of ARTHROSPORES (arthrospores form spherules filled with endospores)

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14
Q

DOC for coccidiodes

A

Amphotericin B or Itraconazole (fluconazole if with meningitis)

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15
Q

Bird droppings, Starlings, bat guano

A

Histoplasma capsulatum

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16
Q

2 forms of asexual spores of H. capsulatum

A

Tuberculate macroconidia(diagnostic) and microconidia (infective)

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17
Q

Histoplasma Hides inside Macrophages

A

develop into budding yeasts inside macrophages, spreads to liver and spleen

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18
Q

Name 2 great mimickers of TB

A

Histoplasmosis and Paragonimus

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19
Q

Round yeast with broad based buds

A

Blastomyces dermatitidis

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20
Q

Most common cause of fungal pneumonia

A

Blastomyces dermatitidis

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21
Q

Transmission of blastomycosis

A

inhalation of conidia

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22
Q

DOC for blastomycosis

A

Itraconazole (amphotericin if severe)

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23
Q

Mariner’s Wheel

A

Paracoccidiodes brasiliensis

24
Q

Transmission of paracoccidioidomycosis

A

Inhalation of conidia

25
Q

DOC for paracoccidiodomycosis

A

Itraconazole

26
Q

5 opportunistic mycoses

A

Candida albicans, Cryptococcus neoformans, Aspergillus fumugatus; Rhizopus oryzae and Mucor spp.; Pneumocystis jiroveci

27
Q

Oval yeast with a single bud or as pseudohyphae

A

Candida albicans

28
Q

Germ tubes in serum and chlamydo-spores in culture

A

Candida albicans

29
Q

DOC for oral thrush from candida

A

Nystatin

30
Q

DOC for skin infections from candida

A

clotrimazole

31
Q

DOC for disseminated candidiasis

A

amphotericin B

32
Q

DOC for chemoprophylaxis for candida

A

fluconazole

33
Q

MCC of fungal septicemia

A

Candida albicans

34
Q

Oval yeast wth narrow based bud surrounded by a wide polysaccharide capsule

A

Cryptococcus neoformans

35
Q

Staining techniques for cryptococcus

A

India ink with Nigrosin

36
Q

Screening test for cryptococcus

A

CALAS (Cryptococcal antigen latex agglutination system)

37
Q

Pigeon droppings

A

Cryptococcus neoformans

38
Q

Transmission of cryptococcus

A

Inhalation of yeasts

39
Q

MCC of meningoencephalitis among AIDS patients

A

Cryptococcus neoformans

40
Q

DOC for Cryptococcus

A

amphotericin B and Flucytosine

41
Q

DOC for chemoprophylaxis for cryptococcus

A

fluconazole

42
Q

septate hyphae that form V-shaped (dichotomous) branches in acute angles

A

Aspergillus fumigatus

43
Q

T or F: Aspergillus fumigatus only exists as MOLDS

A

TRUE!

44
Q

Transmission of aspergillosis

A

inhalation of conidia

45
Q

Asthmatic bronchopulmonary aspergillosis (APBA)

A

Asthmatic bronchopulmonary aspergillosis (APBA)

46
Q

DOC for aspergillosis

A

amphotericin B

47
Q

Saprophytic molds with nonseptate hyphae with walls and branches at right angles

A

Mucormycosis

48
Q

Rhino-orbital-cerebral infection with eschar formation

A

Mucormycosis

49
Q

Patients at risk for mucormycosis

A

DKA, Burns, Leukemia

50
Q

BAL washings stained with toluidine blue and methenamine silver stain

A

Pneumocystis jiroveci

51
Q

Transmission of pneumocystis

A

inhalation of cysts

52
Q

Most common AIDS defining illness

A

Pneumocystis jiroveci

53
Q

Frothy exudate that blocks oxygen exchange

A

Pneumocystis jiroveci

54
Q

Diffuse interstitial pneumonia with ground glass infiltrates

A

Pneumocystis jiroveci

55
Q

DOC for pneumocystis

A

TMP-SMX

PLE Microbiology (10 decks)

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