Mycology and Parasitology Flashcards
What are the 2 main types of fungi?
Define each.
Moulds - “any multicellular filamentous fungus that commonly forms a rough, furry coating on decaying matter”
Yeasts - “any unicellular fungi which may occur singly, in groups of 2 or 3, or in chains”
What are the 2 main types of mould?
Dermatophytes
Other moulds
List the 3 main types of dermatophyte infection.
Scalp infection (tinea capitis) Nail infections (tinea unguium) Skin infections (tinea corporis/barbae/pedis)
What is the most common type of dermatophyte?
Trichophyton
Give some examples of common dermatophytes. (2)
Give some examples of travel-related dermatophytes. (2)
Give some examples of occupation related dermatophytes. (2)
Give some examples of pet related dermatophytes. (2)
COMMON DERMATOPHYTES:
Trichophyton rubrum
Trichophyton interdigitale
TRAVEL-RELATED DERMATOPHYTES:
Trichophyton tonsurans
Trichophyton violaceum
OCCUPATION RELATED DERMATOPHYTES:
Triphyton verrucosum
Microsporum gypseum
PET RELATED DERMATOPHYTES:
Microsporum canis
Trichophyton mentagrophytes
Describe endemic regions for:
a) Trichophyton tonsurans (3)
b) Trichophyton violaceum (2)
TONSURANS:
USA
Western Europe
Africa
VIOLACEUM:
Africa
India
Which investigations would you do for mould infections?
Microscopy
Molecular testing
Dermatophyte cultures
How would you treat dermatophyte mould infections? (6)
ANTIFUNGAL AGENTS:
Terbinafine
Itraconazole
Griseofulvin
OTHER TREATMENTS:
Tea tree oil
Garlic
Antibiotics (for secondary infection)
How would you treat non-dermatophyte mould infections? (3)
ANTIFUNGAL AGENTS:
Amphotericin B
Azoles (e.g. itraconazole)
Caspofungin
List 3 methods of antifungal sensitivity testing.
E-tests/disk diffusion
Sensititre-One
Maldi-Tof
What are the 3 main types of yeast?
Candida
Cryptococcus
Malassezia
Which investigations would you do for yeast infections? (3)
Cultures on chromogenic agar
Commercially available testing kits (e.g. Auxacolour 2)
Maldi-Tof
How would you treat superficial yeast infections? (4)
Fluconazole
Itraconazole
Nustatin
Clotrimazole
How would you treat invasive yeast infections? (4)
Amphotericin B
Fluconazole
Caspofungin
Flucytosine