Mycology and Parasitology Flashcards

1
Q

What are the 2 main types of fungi?

Define each.

A

Moulds - “any multicellular filamentous fungus that commonly forms a rough, furry coating on decaying matter”

Yeasts - “any unicellular fungi which may occur singly, in groups of 2 or 3, or in chains”

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2
Q

What are the 2 main types of mould?

A

Dermatophytes

Other moulds

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3
Q

List the 3 main types of dermatophyte infection.

A
Scalp infection (tinea capitis)
Nail infections (tinea unguium)
Skin infections (tinea corporis/barbae/pedis)
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4
Q

What is the most common type of dermatophyte?

A

Trichophyton

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5
Q

Give some examples of common dermatophytes. (2)

Give some examples of travel-related dermatophytes. (2)

Give some examples of occupation related dermatophytes. (2)

Give some examples of pet related dermatophytes. (2)

A

COMMON DERMATOPHYTES:
Trichophyton rubrum
Trichophyton interdigitale

TRAVEL-RELATED DERMATOPHYTES:
Trichophyton tonsurans
Trichophyton violaceum

OCCUPATION RELATED DERMATOPHYTES:
Triphyton verrucosum
Microsporum gypseum

PET RELATED DERMATOPHYTES:
Microsporum canis
Trichophyton mentagrophytes

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6
Q

Describe endemic regions for:

a) Trichophyton tonsurans (3)
b) Trichophyton violaceum (2)

A

TONSURANS:
USA
Western Europe
Africa

VIOLACEUM:
Africa
India

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7
Q

Which investigations would you do for mould infections?

A

Microscopy
Molecular testing
Dermatophyte cultures

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8
Q

How would you treat dermatophyte mould infections? (6)

A

ANTIFUNGAL AGENTS:
Terbinafine
Itraconazole
Griseofulvin

OTHER TREATMENTS:
Tea tree oil
Garlic
Antibiotics (for secondary infection)

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9
Q

How would you treat non-dermatophyte mould infections? (3)

A

ANTIFUNGAL AGENTS:
Amphotericin B
Azoles (e.g. itraconazole)
Caspofungin

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10
Q

List 3 methods of antifungal sensitivity testing.

A

E-tests/disk diffusion
Sensititre-One
Maldi-Tof

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11
Q

What are the 3 main types of yeast?

A

Candida
Cryptococcus
Malassezia

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12
Q

Which investigations would you do for yeast infections? (3)

A

Cultures on chromogenic agar
Commercially available testing kits (e.g. Auxacolour 2)
Maldi-Tof

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13
Q

How would you treat superficial yeast infections? (4)

A

Fluconazole
Itraconazole
Nustatin
Clotrimazole

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14
Q

How would you treat invasive yeast infections? (4)

A

Amphotericin B
Fluconazole
Caspofungin
Flucytosine

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