Mutations

Question 1

Recessive Mutations

Answer 1

Often involve loss of gene function

Null/amorphic allele
hypomorphic allele

Question 2

Null/Amorphic Alleles

Answer 2

Nonfunctional protein produced, or no protein is produced

Question 3

Hylomorphic alleles

Answer 3

Poorly functioning protein is produced, or reduced amounts of a normally functioning protein is produced

Question 4

Dominant Mutations

Answer 4

Often involve gain/change of gene function

Dominant hypermorphic alleles
Neomorphic alleles

Question 5

Dominant Hypermorphic Alleles

Answer 5

Make too much of the protein, or protein has increased activity

Question 6

Neomorphic Alleles

Answer 6

Protein with a new function is created

New protein interferes with wildtyp protein (dominant negative allele)