Mutations 2 Flashcards

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1
Q

Species with high _ through to be at greater risk of exposure to mutagens through mitochondrial respiration

A

Metabolic rate

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2
Q

Species with high metabolic rate are thought to be at greater risk of exposure to mutagens through _

A

Mitochondrial respiration

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3
Q

More generations through unit of time, greater odds of _ increasing mutation rate

A

DNA replication errors

(Mice 200 generations in 100 years)

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4
Q

During deletion, genetic material _

A

Breaks off

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5
Q

When genetic material breaks off, _ causes frame shift (deletion)

A

Loss of DNA sequence

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6
Q

Larger deletion, more likely _

A

Defect

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7
Q

Cystic fibrosis, lung disease, caused by deletional mutation that changes _ gene

A

CFTR

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8
Q

_ occurs when base replaced by another

A

Substitution

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9
Q

Substitution can have no effect or _

A

Drastic effect

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10
Q

Effect of substitution depends on which _ is substituted and with what

A

Base pair

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11
Q

_ is caused by a substitution mutation

A

Sickle cell anemia

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