Mutations 2 Flashcards
Species with high _ through to be at greater risk of exposure to mutagens through mitochondrial respiration
Metabolic rate
Species with high metabolic rate are thought to be at greater risk of exposure to mutagens through _
Mitochondrial respiration
More generations through unit of time, greater odds of _ increasing mutation rate
DNA replication errors
(Mice 200 generations in 100 years)
During deletion, genetic material _
Breaks off
When genetic material breaks off, _ causes frame shift (deletion)
Loss of DNA sequence
Larger deletion, more likely _
Defect
Cystic fibrosis, lung disease, caused by deletional mutation that changes _ gene
CFTR
_ occurs when base replaced by another
Substitution
Substitution can have no effect or _
Drastic effect
Effect of substitution depends on which _ is substituted and with what
Base pair
_ is caused by a substitution mutation
Sickle cell anemia