Mutation and Gene Editing Flashcards
A change in any single nucleotide of a DNA sequence
Point mutation
The loss of one or more nucleotides in a DNA sequence
Deletions
The addition of one or more extra nucleotides in a DNA sequence
Insertions
What are the three possible results from a point mutation?
Silent, missense, and nonsense
The mutation does not result in a change the amino acid sequence
Silent mutation
A mutation that causes one amino acid in the protein sequence to be changed to a different one
Missense mutation
Which of the following is the CRISPR-Cas9 system in bacteria similar to in the human body?
a. digestive system
b. immune system
c. circulatory system
d. respiratory system
b. immune system
CRISPR refers to repeated sequences in which of the following locations?
a. Bacterial DNA
b. Viral DNA
c. Fungal DNA
d. Viral DNA
a. Bacterial DNA
Which of the following is the gene knockout technique used for investigating?
a. Trauma on brain cells
b. The process of DNA replication
c. The function of a gene
d. Mutation rate
c. The function of a gene
Order the steps and molecules of gene expression, from first to last:
RNA
Protein
Translation
Folding
Polypeptide
Metabolism
Trait
Transcription
DNA
DNA
Transcription
RNA
Translation
Polypeptide
Folding
Protein
Metabolism
True or False: All mutations are “bad.”
False
True or False: Somatic mutations can be passed on to the next generation.
False
True or False: Spontaneous mutations occur during DNA replication.
True
True or False: All forms of electromagnetic radiation can mutate DNA.
False
The mutation that causes sickle cell disease is a nucleotide ________ that results in a __________ mutation.
a. insertion, missense
b. deletion, frameshift
c. substitution, missense
d. substitution, silent
c. substitution, missense
In the sickle cell mutation, the amino acid ____ is replaced with the amino acid ____
a. val, glu
b. glu, val
b. glu, val
