Mutações de genes supressores de tumores Flashcards

1
Q

APC/beta-caderina

2tumores

A

Gastro intestinal e Melanoma

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2
Q

E-caderina

A

Estomago

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3
Q

KLF6

2 tumores

A

Mama e Prostata

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4
Q

NF-1 e NF-2

A

Tumores Neurais

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5
Q

P16 (INK4a)

2 tumores

A

Gastro intestinal e Mama

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6
Q

p53

A

tudo

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7
Q

RB

A

Retinoblastoma

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8
Q
APC/beta-caderina
CDKN2A (p16 e p14)
BRAF
Ras
FGF3
A

Melanoma

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9
Q

SMADs

A

Gastro intestinal

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10
Q

TGF-beta

A

colon

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11
Q

WT-1

A

Tumor de wilms

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12
Q

Gastro intestinal

A

APC/beta-canderina
P16 (INK4a)
SMADs

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13
Q

Colon

A

TGF-beta
APC/beta-canderina
P16
SMADs

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14
Q

Melanoma

A
APC/beta-caderina
CDKN2A (p16 e p14)
BRAF
Ras
FGF3
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15
Q

Estomago

A

E-caderina

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16
Q

Mama

A

KLF6

p16

17
Q

Prostata

A

KLF6

18
Q

Tumores neurais

A

NF-1 e NF-2

19
Q

TUDO

A

p53

20
Q

Retinoblastoma

A

Rb

21
Q

Tumor de Wilms

A

WT-1