Muster-Body Fluid Compartments

Question 1

Osmolality

Answer 1

Total free solute per kg of solvent

Question 2

Osmolarity

Answer 2

Total free solute per Liter of solvent

Question 3

mM of Na+ in plasma?

Answer 3

140 mM

Question 4

mM of Cl- in plasma?

Answer 4

105 mM

Question 5

mM of HCO3- in plasma?

Answer 5

25 mM

Question 6

mM of urea in plasma?

Answer 6

6 mM

Question 7

Total osmolality of plasma?

Answer 7

300 mM

Question 8

What is the protein critical to fluid shift and placement?

Answer 8

Albumin

Question 9

What is the anion gap? what is the normal range?

Answer 9

Na+ - (Cl- + HCO3-)

Normally 8-12

Question 10

What prevents a rapidly growing vasacular space due to fenestration of the capillary walls?

Answer 10

Blood pressure! Hydrostatic pressure

Question 11

Oncotic pressure within a capillary favors what?

Answer 11

Fluid movement INTO capillary (reabsorption)

Question 12

Hydrostatic pressure within the capillary favors what?

Answer 12

Fluid movement out of the capillary (filtration)

Question 13

Hydrostatic pressure within the interstitial space favors what?

Answer 13

Fluid movement out of the interstitial space (reabsorption)

Question 14

Oncotic pressure within the interstitial space favors what?

Answer 14

Fluid movement INTO the interstitial space (filtration)

Question 15

What is the equation for forces of filtration and reabsorption?

Answer 15

Kf(Forces favoring filtration)-(forces favoring reabsorption)
Kf(Hydrostatic pressure in capillary + oncotic pressure in interstitium) -(hydrostatic pressure in interstitium + oncotic pressure in capillary)

Question 16

What is the intracellular amount of Potassium?

Answer 16

140 mM

Question 17

What is the intracellular amount of PO4-?

Answer 17

20 mM

Question 18

what is the intracellular amount of Cl-?

Answer 18

20 mM

Question 19

What drug shuts down the Na+/K+ pump between the cell and the interstitium?

Answer 19

Digitalis!

Question 20

How does the intracellular level of potassium get so high?

Answer 20

Sodium moves into the cell.
Chloride follows.
Water follows.
The Na+/K+ ATPas pumps sodium out of the cell and Potassium in to keep the cells from bursting.

Question 21

Isosmotic?

Answer 21

Any solution that has about 300 mOsoms since our physiologic reference is about 300 mOsom.

Question 22

What does isotonic mean?

Answer 22

Any solution that will NOT change the volume of a cell. Need 300 mOsom of impermeable solutes.

Question 23

What is the osmolality of normal saline?

Answer 23

308 mmol/L

Question 24

How much sodium is in normal saline? chloride?

Answer 24

154 mmol/L for each

Question 25

Is there potassium, bicarbonate, or glucose in NS (0.9 %)

Answer 25

NO

Question 26

What is the osmolality of 1/2NS (.45%)?

Answer 26

150 mmol/L (75 mmol/L each of sodium and chloride)

Question 27

What is the osmolality of D5?

Answer 27

300 mmol/L

Question 28

What is the amount of glucose in D5?

Answer 28

280 mmol/L

Question 29

What percentage of the total body volume is water?

Answer 29

60 %

Question 30

How much of your total body water is intracellular?

Answer 30

2/3

Question 31

How much of your total body water is extracellular?

Answer 31

1/3

Question 32

What amount of the extracellular water is interstitial?

Answer 32

3/4

Question 33

What amount of the extracellular water is in plasma (intravascular)?

Answer 33

1/4

Question 34

What happens to the water distribution if you drink 1000 mL of water?

Answer 34

It will distribute proportionately according to the volume of the compartments (333 mL interstitial-3/4 of this interstitial, 1/4 of this in plasma) and 66 mL intracellular