Musculoskeletal System Flashcards

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1
Q

What is osteoarthritis?

A

Progressive degeneration of joint cartilage and underlying bone. Causes pain and stiffness.

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2
Q

What conclusions have been made regarding regenerative knee therapies?

A

Not sufficient evidence to recommend a single method for treating knee cartilage defects.

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3
Q

What is the primary reason for revision surgery in joint replacements?

A

Aseptic lossening.

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4
Q

What is tribology?

A

Study of friction, wear, lubrication and the design of bearings. The science of interacting surfaces in relative motion.

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5
Q

What material choices are their for replacement joint materials?

A

Typically use combinations of metal, plastic (UHMWPE) or ceramic for cup and head.

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6
Q

What are the three main lubrication regimes and the lambda values associated with them?

A
  1. Boundary lubrication (lambda < 1)
  2. Mixed lubrication (1 < lambda < 3)
  3. Hydrodynamic/fluid film lubrication (lambda > 3)
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7
Q

Based on the film thickness equation for elastohydrodynamic lubrication, how can increased possibility of fluid film lubrication (lambda > 3) be achieved?

A

Increasing head radius, R, to increase the minimum film thickness h_min.

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8
Q

What is elastohydrodynamic lubrication?

A

A lubrication regime in which significant elastic deformation of the surfaces takes place. Deformations exceed film thickness.
Alters the shape and thickness of the lubricant film in the contact.

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9
Q

Why are large diameter MoM hips no longer used?

A

Large metal head with reduced stem taper created mechanically assisted crevice corrosion (MACC) at taper junction.

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10
Q

What can be learned from the failure of MoM hips?

A
  • Need appropriate pre-clinical testing.
  • Phased introduction.
  • Need detailed post-market surveillance.
  • Balance commercial pressures with patient safety.
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